教育经历：

(1) 2010-09 至 2015-12, 厦门大学, 微生物学, 博士

(2) 2009-09 至 2010-06, 北京邮电大学, 研究生预科, 其他

(3) 2007-09 至 2009-06, 武汉轻工大学, 生物工程, 学士

工作经历：

(1) 2016-01 至 2020-03, 厦门大学

(1) 2020-04 至 今, 西安交通大学, 第二附属医院, 教授

研究领域：

感染和炎症与固有免疫调节

神经免疫调节与认知障碍

肿瘤免疫治疗机制

免疫缺陷病与感染性和非感染性炎症

主持或参加的基金项目：

1. 国家自然科学基金委员会, 面上项目, 32370922, Fam26F在巨噬细胞抗感染应激中的作用与机制研究, 2024-01-01 至 2027-12-31, 50万元, 在研, 主持
2. 西安市科技局, 国际科技合作基地, SXSKXJST-2021-004962, 细胞应激与疾病诊疗国际科技合作基地, 2021-01 至 今, 50万元, 在研, 主持
3. 中华人民共和国科学技术部, 国家重点研发计划, 2021YFA1100702, 人干细胞向调节型和效应型免疫细胞的分化与功能优化研究, 2021-12 至 2026-06, 600万元, 在研, 参与
4. 国家自然科学基金委员会, 面上项目, 32070891, 激酶Mst3/4对巨噬细胞极化与可塑性的影响与作用机制, 2021-01-01 至 2024-12-31, 58万元, 在研, 主持
5. 中共陕西省省委组织部, 陕西省“千人计划”青年项目, YJ0866, 免疫分子功能与固有免疫应答, 2020-01 至 2022-12, 80万元, 在研, 主持
6. 国家自然科学基金委员会, 重点项目, 81830046, 激酶NDR1/2在机体抗感染应激中免疫调节与宿主防御的作用机制与功能研究, 2019-01-01 至 2023-12-31, 295万元, 在研, 参与
7. 国家自然科学基金委员会, 重大项目, 81790254, 探索肿瘤微环境中的代谢波动对炎症和肿瘤免疫的影响和机制, 2018-01-01 至 2022-12-31, 365.4万元, 结题, 参与
8. 中国科学技术协会, 青年人才托举工程, YESS20170159, Hippo通路与固有免疫应答, 2017-01 至2019-12, 45万元, 结题, 主持
9. 中国博士后基金会, 特别资助项目, 2017T100470, WWTR1在TH17和Treg细胞中的功能及机理研究, 2017-01 至 2018-12, 15万元, 结题, 主持
10. 中国博士后基金会, 面上项目, 2016M602072, Mst1/2-PKC信号通路对转录因子Nrf2的调控机制研究, 2016-01 至 2017-12, 5万元, 结题, 主持
11. 国家自然科学基金委员会,青年科学基金项目, 31600698, Mst1和Mst2激酶调节吞噬细胞抗氧化应激的作用机制研究, 2017-01-01至 2019-12-31, 20万元,  结题, 主持

代表性研究成果

1. Jin Sun; Yingnan Li; Mengjiao Shi; Hongwei Tian; Jun Li; Kai Zhu; Ying Guo; Yanhua Mu; Jing Geng*; Zongfang Li* ; A Positive Feedback Loop of lncRNA HOXD-AS2 and SMYD3 Facilitates Hepatocellular Carcinoma Progression via the MEK/ERK Pathway, Journal of Hepatocellular Carcinoma, 2023, 2023:10 : 1237-1256
2. Yang Zhao; Rui Zhou; Ying Guo; Xi Chen; Aiyu Zhang; Jiayin Wang; Fanpu Ji; Bowen Qin; Jing Geng; Guangyao Kong; Zongfang Li*; Improvement of gut microbiome and intestinal permeability following splenectomy plus pericardial devascularization in hepatitis B virus-related cirrhotic portal hypertension, Frontiers in Immunology, 2022, 13(0)
3. Shaoying Zhang; Dan Wan; Mengchen Zhu; Guihu Wang; Xurui Zhang; Na Huang; Jian Zhang; Chongyu Zhang; Qi Shang; Chen Zhang; Xi Liu; Fanfan Liang; Chunyan Zhang; Guangyao Kong; Jing Geng; Libo Yao; Shemin Lu*; Yongyan Chen*; Zongfang Li*; CD11b+ CD43hi Ly6Clo splenocyte-derived macrophages exacerbate liver fibrosis via spleen-liver axis., Hepatology, 2022, 0(0)  
4. Liu, Qingxu^#; Li, Jiaxin^#; Zhang, Weiji^#; Xiao, Chen^#; Zhang, Shihao^#; Nian, Cheng; Li, Junhong; Su, Dongxue; Chen, Lihong; Zhao, Qian; Shao, Hui; Zhao, Hao; Chen, Qinghua; Li, Yuxi; Geng, Jing; Hong, Lixin; Lin, Shuhai; Wu, Qiao; Deng, Xianming; Ke, Rongqin; Ding, Jin; Johnson, Randy L.; Liu, Xiaolong; Chen, Lanfen*; Zhou, Dawang*; Glycogen accumulation and phase separation drives liver tumor initiation, Cell, 2021, 184(22): 5559-5576
5. Geng, Jing^#; Shi, Yiran^#; Zhang, Jinjia^#; Yang, Bingying; Wang, Ping; Yuan, Weihong; Zhao, Hao; Li, Junhong; Qin, Funiu; Hong, Lixin; Xie, Changchuan; Deng, Xianming; Sun, Yujie; Wu, Congying; Chen, Lanfen*; Zhou, Dawang*; TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection, Nature Communications, 2021, 2021(3519): 0-3519   
6. Wang, Ping^#; Geng, Jing^#; Gao, Jiahui; Zhao, Hao; Li, Junhong; Shi, Yiran; Yang, Bingying; Xiao, Chen; Linghu, Yueyue; Sun, Xiufeng; Chen, Xin; Hong, Lixin; Qin, Funiu; Li, Xun; Yu, Jau Song; You, Han; Yuan, Zengqiang; Zhou, Dawang; Johnson, Randy L; Chen, Lanfen*; Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis, Nature Communications, 2019, 10(755)
7. Ji, Suyuan^#; Liu, Qingxu^#; Zhang, Shihao^#; Chen, Qinghua^#; Wang, Cong; Zhang, Weiji; Xiao, Chen; Li, Yuxi; Nian, Cheng; Li, Jiaxin; Li, Junhong; Geng, Jing; Hong, Lixin; Xie, Changchuan; He, Ying; Chen, Xing; Li, Xun; Yin, Zhen Yu; You, Han; Lin, Kwang Huei; Wu, Qiao; Yu, Chundong; Johnson, Randy L; Wang, Li; Chen, Lanfen; Wang, Fen; Zhou, Dawang*; FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis, Developmental Cell, 2019, 48(4): 460-474
8. Hong, Lixin; Li, Xun; Zhou, Dawang; Geng, Jing; Chen, Lanfen*; Role of Hippo signaling in regulating immunity, Cellular and Molecular Immunology, 2018, 15(12): 1003-109
9. Geng, Jing^#; Yu, Shujuan^#; Zhao, Hao^#; Sun, Xiufeng^#; Li, Xun; Wang, Ping; Xiong, Xiaolin; Hong, Lixin; Xie, Changchuan; Gao, Jiahui; Shi, Yiran; Peng, Jiaqi; Johnson Randy L; Xiao, Nengming; Lu, Linrong; Han, Jiahuai; Zhou, Dawang*; Chen, Lanfen*; The transcriptional coactivator TAZ regulates reciprocal differentiation of T(H)17 cells and T-reg cells, Nature Immunology, 2017, 18(7): 800-812
10. Zhang, Shihao^#; Chen, Qinghua^#; Liu, Qingxu^#; Li, Yuxi; Sun, Xiufeng; Hong, Lixin; Ji, Suyuan; Liu, Chengyan; Geng, Jing; Zhang, Weiji; Lu, Zhonglei; Yin, Zhen Yu; Zeng, Yuanyuan; Lin Kwang Huei; Wu, Qiao; Li, Qiyuan; Nakayama Keiko; Nakayama Keiich I; Deng, Xianming; Johnson Randy L; Zhu, Liang; Gao, Daming; Chen, Lanfen*; Zhou, Dawang*; Hippo signaling suppresses cell ploidy and tumorigenesis through Skp2, Cancer Cell, 2017, 31(5): 669-684     
11. Fan, Fuqin^#; He, Zhixiang^#; Kong, Lu Lu^#; Chen, Qinghua^#; Yuan, Quan^#; Zhang, Shihao; Ye, Jinjin; Liu, Hao; Sun, Xiufeng; Geng, Jing; Yuan, Lunzhi; Hong, Lixin; Xiao, Chen; Zhang, Weiji; Sun, Xihuan; Li, Yunzhan; Wang, Ping; Huang, Lihong; Wu, Xinrui; Ji, Zhiliang; Wu, Qiao; Xia, Ning Shao; Gray Nathanael S; Chen, Lanfen; Yun, Cai Hong*; Deng, Xianming*; Zhou, Dawang*; Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration, Science Translational Medicine, 2016, 8(352)
12. Geng, Jing^#; Sun, Xiufeng^#; Wang, Ping; Zhang, Shihao; Wang, Xiaozhen; Wu, Hongtan; Hong, Lixin; Xie, Changchuan; Li, Xun; Zhao, Hao; Liu, Qingxu; Jiang, Mingting; Chen, Qinghua; Zhang, Jinjia; Li, Yang; Song, Siyang; Wang, Hong-Rui; Zhou, Rongbin; Johnson, Randy L; Chien, Kun-Yi; Lin, Sheng-Cai; Han, Jiahuai; Avruch, Joseph; Chen, Lanfen*; Zhou, Dawang*; Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity, Nature Immunology, 2015, 16(11): 1142-1152
13. Wu, Hongtan^#; Wei, Luyao^#; Fan, Fuqin; Ji, Suyuan; Zhang, Shihao; Geng, Jing; Hong, Lixin; Fan, Xin; Chen, Qinghua; Tian, Jing; Jiang, Mingting; Sun, Xiufeng; Jin, Changnan; Yin, Zhen-Yu; Liu, Qingxu; Zhang, Jinjia; Qin, Funiu; Lin, Kwang-Huei; Yu, Jau-Song; Deng, Xianming; Wang, Hong-Rui; Zhao, Bin; Johnson, Randy L; Chen, Lanfen*; Zhou, Dawang*; Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis., Nature Communications, 2015, 6(6239)    
14. Wu, Hongtan^#; Xiao, Yubo^#; Zhang, Shihao^#; Ji, Suyuan; Wei, Luyao; Fan, Fuqin; Geng, Jing; Tian, Jing; Sun, Xiufeng; Qin, Funiu; Jin, Changnan; Lin, Jianjun; Yin, Zhen-Yu; Zhang, Ting; Luo, Lianzhong; Li, Yang; Song, Siyang; Lin, Sheng-Cai; Deng, Xianming; Camargo, Fernando; Avruch, Joseph; Chen, Lanfen*; Zhou, Dawang*; The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense, Cell Reports, 2013, 3(5): 1663-1677
15. Geng, Jing; Xiao, Shuyan; Zheng, Zhonghui; Song, Siyang; Zhang, Lianru*; Gambogic acid protects from endotoxin shock by suppressing pro-inflammatory factors in vivo and in vitro, Inflammation Research, 2012, 62(2): 165-172