基本信息

 

 

工作经历与学术任职

工作经历：

2009.09-2013.01: 助理研究员/兼任学术秘书，脑影像研究组责任老师。中国科学院自动化研究所复杂系统智能控制管理国家重点实验室，田捷研究员课题组

2013.02-2018.12:  副教授/博士生导师，西安交通大学生命科学与技术学院生物医学信息工程教育部重点实验室

2016. 01-2017.1:  哈佛大学麻省总医院神经科学系，助理教授；放射学系访问副教授

2019.1-present：教授，西安交通大学生命科学与技术学院生物医学信息工程教育部重点实验室

 

学术任职情况：

常委/学术副秘书长，中国针灸学会针刺医学影像专业委员会（国家二级学会），2014-date

副理事长/学术副秘书长，脑科学产学研创新联盟,2017-date

世界华人神经创伤学会，委员（2023-date）

编委及客座主编，Evidence-Based Complementary and Alternative Medicine, 2012-date

客座主编, Neural Plasticity, 2017

编委，ISRN Radiology, 2012-date

责编，BMC Complementary and Alternative Medicine, 2012-date

编委及客座主编，BioMed Research International, 2012-date

编委，Humanitas Traditional Medicine, 2012-date

编委，Dataset Papers in Medicine, 2012-date

新闻

招生信息

本课题组招收以下方向的研究生欢迎有志青年咨询报考，同时也欢迎短期访问交流学生来实验室学习交流。

生命学院研究生办公室，王老师 联系电话：029-82669021

 
I. 生物医学工程学科（工学硕士，博士，博士后） 返回顶部
  1. 医学信号处理及医学仪器
  2. 脑神经及认知科学
  3. 医学成像及图像处理
  4. 脑行为意识识别及信号处理技术
 
II. 医学（硕士，博士，博士后） 返回顶部
  1. 脑认知与神经信息干预机制研究
  2. 脑功能信息检测及神经动力学
  3. 脑功能障碍及其干预方法研究

 

合作交流

课题组已与美国哈佛大学麻省总医院生物医学工程系，美国佛罗里达生物医学工程系以及精神病学系，美国密歇根大学，美国马里兰大学中西医结合研究中心，香港大学中医药学院建立了长期良好的合作关系，联合开展了实质性研究与博士联合培养计划。

课题组在开展实验方面，已与亚洲最大的神经影像基地北京天坛医院（放射科，核医学科以及神经内科），宣武医院（放射科及神经内科），北京东直门医院（神经 内科与影像科），北京中医医院，广安门中医医院，深圳宝安人民医院等国内著名的影像基地及中西医结合基地建立了稳定广泛的合作关系。

课题组在校内合作方面，已和交大医学院及第一附属医院建立了紧密的合作关系，并联合培养学生。


 

联系方式

办公地址：生命学院教二楼319室

     QQ：   519524392

电子邮箱：bailijun@xjtu.edu.cn

站点计数器

个人简介

 

白丽君，女，工学博士学位（电子科学与技术）,西安交通大学生命科学与技术学院教授（博士生导师）。

 

研究方向

1.磁共振成像技术与图像处理算法研发，脑科学与脑认知，数据质控及标准化成像采集方案研发

2.基于医学影像与标记物海量数据的人工智能影像组学研究与应用

3.X射线及锥束CT成像系统及软件平台研发

4.基于脑-肠轴调控的脑损伤人鼠联合临床转化实验平台

 

在国家重点研发计划、国自然面上项目（5项）的连续资助下，团队负责人以第一及通讯作者在 Top 期刊J Neurol Neurosurg Psychiatry (IF: 13.65)、BJPsy (IF: 10.56，封面论文并获编辑亮点推荐)、J Neurotrauma (IF: 5.27，封面论文)等发表论文近百篇。研究得到美国医学与生物工程院院士、国际头疼学期刊创始主编、国际头痛分类临床指南总负责等发表在 Nat Neurosci Rev（34.87）、J Clin Oncol (IF：44.54)等期刊的专题评述。我国疼痛学科创始人/针刺研究权威韩济生院士发表《全球针刺研究发展趋势》专题综述评价研究工作：“指出了前人脑响应估计函数背离了针刺自身特性的事实，并提出了适合针刺脑响应的分析方法。”相关研究工作还被写入国际现行卒中康复治疗指南 EBRSR。在中国针灸学会副会长石学敏院士担任执行主席的“针刺穴位组学”第364期香山科学会议上，与会专家达成共识，将团队提出的脑科学时变建模方法予以行业内推广与临床验证。脑创伤早期诊断与识别的相关研究成果已在神经外科国家重点专科获得临床应用。
团队负责人先后获得陕西省科技进步二等奖、北京市科技进步二等奖、中国自动化学会自然科学一等奖等省部级奖项5项。入选陕西省杰出青年、陕西省青年科技新星、北京市科技新星等。出版学术专著5部，包括获得了我国新闻出版界最高奖项“国家出版政府奖”、入选国家“十二五”重点出版物、新中国70年百种译介图书推荐目录等。

 

主持项目情况

1. 国家重点研发计划，课题负责人，慢性萎缩性胃炎与胃癌前病变的中医药诊疗规律系统化研究，2023YFC3503600，2023.11-2027.10, 课题承担经费400万（项目批复总经费2200万）

2. 国防基础加强项目，项目负责人，2022-2024,140万。

3.陕西省杰出青年基金项目，项目负责人，针刺疗效影像学评价及临床应用，2022JC-55，2022.1-2024.12,50万

4. 国家重点研发计划，课题负责人，新生儿局灶性白质损伤预后评估的磁共振成像新技术集成及其临床应用, 2016.07-2018.12,340万  

5.国家自然科学基金面上项目，项目负责人，“微血管损伤”驱动的轻度脑外伤诱发AD关联病变新机制及风险预测，2021-2024,56万

6.国家自然科学基金面上项目, 资助号81771914, 2018-2021,65万

7.国家自然科学基金面上项目，资助号：81571752, 2016-2019，71万

8.国家自然科学基金面上项目, 资助号:81371630, 2014-2017，70万

9.国家自然科学基金面上项目, 资助号：81071217, 2011-2013，32万

10.国家重点研发计划课题，资助号:2016YFC0100303,2016-2018,340万

11.北京市科技新星计划, 资助号:Z111101054511116,2012-2014,20万

12.北京市自然科学基金面上项目, 资助号：4122082,2012-2014,11万

 

学术骨干参与项目情况  

1. 国家重点基础研究发展计划（973计划）资助号：2011CB707700, 2011-2015，2650万

2. 中国科学院知识创新工程重要方向项目，资助号：KGCX2-YW-129 2009-2013，500万

3. 国家自然科学基金、国家重大科研仪器研制专项，资助号：81227901 2013-2017，8500万

4. 国家自然科学基金重大研究计划，资助号：90209008,2003-2006，120万; 结题评为优秀,并追加一年经费

5. 国家自然科学基金重点项目,循经取穴治疗偏头痛的中枢响应网络研究,资助号: 30930112, 2010-2013, 170万.

 

另主持横向课题十余项

学术获奖

学术获奖

科研获奖及入选人才计划情况:

2022年度：陕西省杰出青年

2015年度: 西安交通大学首届“十大学术新人”奖

2014年度: 陕西省青年科技新星(西安交通大学共入选6名)

2015年度：三秦人才特殊津贴

2014年度: 北京市科学技术奖二等奖（第四完成人）

2014年度: CAA自然科学奖一等奖（第四完成人）

2014年度: 中国体视学学会科学技术一等奖（第四完成人）

2012年度: 北京市青年科技新星(中国科学院全系统共入选3名)

2011年度: 陕西省科学技术二等奖（第二完成人）

2011年度: 陕西高等学校科学技术一等奖（第二完成人）

 

指导学生获奖：

2013年度：指导学生获校级本科生优秀毕业设计奖（学院每年一项）

2015年度：指导学生获校级本科生优秀毕业设计奖（学院每年一项）

2016年度：指导学生获校级本科生优秀毕业设计奖（学院每年一项）

2017年度：指导学生获得全国放射学年会优秀论文一等奖

论文情况

国际SCI检索期刊论文

  1. Xuan Niu#, Lijun Bai#*, Yingxiang Sun, Shan Wang, Jieli Cao, Chuanzhu Sun, Zhuonan Wang, Hui Xu, Shuoqiu Gan, Gen Fan, Wenmin Huang, Chenghui Gu, Bo Yin, Guanghui Bai, Xiaoling Xu, Ming Zhang*, Disruption of periaqueductal gray-default mode network functional connectivity predicts persistent post – traumatic headache in mild traumatic brain injury, 2018, Journal of Neurology, Neurosurgery & Psychiatry (SCI IF: 13.65, 1区, 神经外科学Top期刊).
  2. Yibin Xi#, Xusha Wu#, Longbiao Cui#, Lijun Bai#, Shuoqiu Gan, Xiaoyan Jia, Xuan Li, Yongqiang Xu, Xiaowei Kang, Fan Guo, Hong Yin. Neuroimaging-based brain-age prediction of first-episode schizophrenia and the alteration of brain age after early medication. Br J Psychiatry. 2021 Dec 2:1-8. doi: 10.1192/bjp.2021.169. Epub ahead of print. PMID: 35049480. (IF = 11.171, BJPsy的封面论文，并获编辑亮点推荐及专题评述)
  3. Xuan Niu, Lijun Bai*, Yingxiang Sun, Yuan Wang, Guanghui Bai, Bo Yin, Shan Wang, Shuoqiu Gan, Xiaoyan Jia, Hongjuan Liu*. Mild traumatic brain injury is associated with effect of inflammation on structural changes of default mode network in those developing chronic pain, Journal of headache and pain. 2020.1. IF = 8.588
  4. Yizhen Pan#, Xuan Li#, Yuling Liu, Xiaoyan Jia, Shan Wang, Qiuyu Ji, Wenpu Zhao, Bo Yin, Guanghui Bai, Jie Zhang*, Lijun Bai*, Hierarchical brain structural-functional coupling associated with cognitive impairments in Mild Traumatic BrainInjury, Cereb Cortex, 2023.
  5. Xuan Li. Xiaoyan Jia, Yuling Liu, Guanghui Bai, Yizhen Pan, Qiuyu Ji, Zhaoyi Mo, Wenpu Zhao, Yixin Wei, Shan Wang, Bo Yin, Jie Zhang*, Lijun Bai*. Brain dynamics in triple-network interactions and its relation to multiple cognitive impairments in mild traumatic brain injury. Cereb Cortex, 2023, bhac529
  6. Xiaoyan Jia, Xuan Li, Qiuyu Ji, Bo Yin, Yizhen Pan, Wenpu Zhao, Guanghui Bai, Jie Zhang, Lijun Bai*. Serum biomarkers and disease progression in CT-negative mild traumatic brain injury. Cereb Cortex. 2023.
  7. Shuoqiu Gan, Wen Shi, Shan Wang, Yingxiang Sun, Bo Yin, Guanghui Bai, Xiaoyan Jia, Chuanzhu Sun, Xuan Niu, Zhuonan Wang, Xiaofan Jiang, Jun Liu, Ming Zhang, Lijun Bai*. Accelerated Brain Aging in Mild Traumatic Brain Injury: Longitudinal Pattern Recognition with White Matter Integrity. J Neurotrauma. 2021 May 19.
  8. Zhuonan Wang#, Ming Zhang*, Chuanzhu Sun#, Shan Wang#, Jieli Cao, Kevin K. W. Wang, Shuoqiu Gan, Wenmin Huang, Xuan Niu, Yanan Zhu, Yingxiang Sun, Lijun Bai*. Single mild traumatic brain injury deteriorates progressive inter-hemispheric functional and structural connectivity, J Neurotrauma. 2019. doi: 10.1089/neu.2018.6196 (SCI IF: 5.28, 1区, 美国国家脑创伤学会主刊, 27年来国内唯一封面论文).
  9. Xiaoyan Jia, Xuebin Chang, Lijun Bai*, Yulin Wang, Debo Dong, Shuoqiu Gan, Shan Wang, Xuan Li, Xuefei Yang, Yinxiang Sun, Tianhui Li, Feng Xiong, Xuan Niu, Hao Yan. A Longitudinal Study of White Matter Functional Network in Mild Traumatic Brain Injury. J Neurotrauma. 2021 May 28.
  10. Shan Wang, Shuoqiu Gan, Xuefei Yang, Tianhui Li, Feng Xiong, Xiaoyan Jia, Yingxiang Sun, Jun Liu, Ming Zhang, Lijun Bai*. Decoupling of structural and functional connectivity in hubs and cognitive impairment after mild traumatic brain injury. Brain Connect. 2021 Feb 19.
  11. Yingxiang Sun, Shan Wang, Shuoqiu Gan, Xuan Niu, Bo Yin, Guanghui Bai, Xuefei Yang, Xiaoyan Jia, Lijun Bai*, Ming Zhang. Serum Neuron-Specific Enolase Levels Associated with Connectivity Alterations in Anterior Default Mode Network after Mild Traumatic Brain Injury. J Neurotrauma. 2021 Jun 1;38(11):1495-1505.
  12. Xiao Han, He Jin, Kuangshi Li, Yanzhe Ning, Lan Jiang, Pei Chen, Hongwei Liu, Yong Zhang, Hua Zhang, Zhongjian Tian, Fangyuan Cui, Yi Ren, Lijun Bai*, Yihuai Zou*. Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis. Nerual Plast. 2020 Aug 19; 2020:8838498.
  13. Zhuonan Wang, Lijun Bai*, Qi Liu, Shan Wang, Chuanzhu Sun, Ming Zhang*, Yumei Zhang. Corpus callosum integrity loss predicts cognitive impairment in Leukoaraiosis. Annals of Clinical and Translational Neurology, 2020.12, 7:2409-2420.
  14. Lijun Bai*, Tuo Zhang, XiNian Zuo, Mingzhou Ding. Editorial: Balancing Act: Structural-Functional Circuit Disruptions and Compensations in Developing and Aging Brain Disorders. Front Neural Circuits, 2020, 13: Article 83. 
  15. Lijun Bai*, Guanghui Bai, Shan Wang, Xuefei Yang, Shuoqiu Gan, Xiaoyan Jia, Bo Yin, Zhihan Yan. Strategic white matter injury associated with long-term information processing speed deficits in mild traumatic brain injury. Human Brain Mapping, 2020.10,41:4431-4441. 
  16. Yingxiang Sun#, Lijun Bai *#, Xuan Niu, Zhuonan Wang, Bo Yin, Guanghui Bai, Danbin Zhang, Shuoqiu Gan, Chuanzhu Sun, Shan Wang, Feng Zhu*, Ming Zhang*. Elevated Serum Levels of Inflammation-Related Cytokines in Mild Traumatic Brain Injury Are Associated With Cognitive Performance. Frontiers in Neurology, 2019, 10: 1120. doi: 10.3389/fneur.2019.01120.
  17.  Guanghui Bai#, Lijun Bai#, Jieli cao#, Chuanzhu Sun, Shan Wang, Bo Yin, Jingfei Zhuang, Zhuonan Wang, Shuoqiu Gan, Xuan Niu, Wenmin Huang, Hui Xu, Meihua Shao, Zhihan Yan, Ming Zhang*, Sex Differences in Cerebral Perfusion Changes after Mild Traumatic Brain injury: Longitudinal Investigation and Correlation with Outcome. Brain Research, 2019,1708: 93-99.
  18.  Shan Wang#, Liuxun Hu#, Jieli Cao, Wenmin Huang, Chuanzhu Sun, Dongdong Zheng, Zhuonan Wang, Shuoqiu Gan, Xuan Niu, Chenghui Gu, Guanghui Bai, Limei Ye, Danbin Zhang, Nu Zhang, Bo Yin*, Ming Zhang*, Lijun Bai*. Sex Differences in Abnormal Intrinsic Functional Connectivity after Acute Mild Traumatic Brain Injury, Frontiers in Neural Circuits, 2018, 12: Article 107.
  19.  Lijun Bai#, Meihua Shao#, Jieli Cao#,, Wenming Huang, Shan Wang, Chuanzhu Sun, Shuoqiu Gan, Limei Ye, Bo Yin, Danbin Zhang, Chenghui Gu, Liuxun Hu, Guanghui Bai*, Zhihan Yan*, Preliminary Evidence of Sex Differences in Cortical Thickness Following Acute Mild Traumatic Brain Injury, Frontiers in Neurology, 2018, 9: Article 878. (中科院II区)
  20. Hui Xu, Xiaocui Wang, Zhen Chen, et al Ming Zhang* and Bai L* (2018) Longitudinal Changes of Caudate-Based Resting State Functional Connectivity in Mild Traumatic Brain Injury. Frontiers in Neurology, 9, Article 467. (中科院II区)
  21. Bai L†, Niu X†, Liu Z†, Chen Z, et al, Jie Tian*, Lixing Lao, and Ming Zhang* (2018) The role of insula-cerebellum connection underlying aversive regulation with acupuncture. Molecular Pain, 14: 1-11. (中科院II区)
  22. Bai L, Sun C, Wang S, et al. (2018) Early Fiber-specific white matter reductions associated with 6-12 months outcome following mild traumatic brain injury. Radiology, Major revision. (中科院I区)
  23. Wang Z, Sun C, Wang S, et al, Bai L*. (2018) Single mild TBI deteriorates progressive interhemispheric functional and structural connectivity. J Neurotrauma, In press. (SCI IF:5.002)
  24. Wang X, et al., Bai L*. (2018) Reorganized hubs of brain functional networks following very early stage of mild traumatic brain injury. Brain Imaging and Behavior, Major revision. (中科院II区)
  25. Bo Yin, Bai L*, Sun C, et al., Zhang M*. (2018) Longitudinal changes in diffusion tensor imaging following mild traumatic brain injury and correlation with outcome. Fronteriors in Neural Circuits. In Press. (中科院II区)
  26. Bai G, Bai L*, Cao J†, et al., Zhang M*. Sex Differences in Cerebral Perfusion Changes after Mild Traumatic Brain injury: Longitudinal Investigation and Correlation with Outcome. Brain Research. In press. (中科院II区)
  27. Niu X, Bai L*, et al., Zhang M*. （2018）Disruption of periaqueductal gray-default mode network functional connectivity predicts persistent post - traumatic headache in mild traumatic brain injury. J Neurol Neurosurg Psychiatry.   0：1-14. IF：8.2 中科院I区
  28. Niu X, Zhang M, Liu Z, Bai L*, Sun C, Shan Wang, Xiaocui Wang, Zhen Chen, Hongyan Chen, Jie Tian* (2017) Interaction of acupuncture treatment and manipulation laterality modulated by the default mode network, Molecular Pain, 13: 1-14. (中科院II区)
  29. Lijun Bai*, Lin Ai, Kevin K. W. Wang, Imaging Neural Plasticity following Brain Injury, Neural Plasticity, 2017, 2017: ID 2083294. (中科院II区)
  30. Qin W†, Bai L †., Liu Z., Liu P., Zhang Y., Liu J., Yuan K., Zhao B., Dai J.*, Liu Y.*, Tian J*. (2015) How the ancient art of acupuncture works: Neuroimaging studies shed light on brain activity in Advances in Computational Psychophysiology (Science/AAAS, Washington, DC, 2015), p. 38-40. This is a sponsored supplement, published together with the 2 October 2015 issue of Science.
  31. Gao L†, Bai L†, Zhang Y, Dai X, Netra R, Min Y, Zhou F, Niu C, Dun W, Gong H, Zhang M. (2015) Frequency-Dependent Changes of Local Resting Oscillations in Sleep-Deprived Brain. PLoS One. 10(3): e0120323.
  32. Gao L, Zhang M., Gong H., Bai L*, Dai X., Min Y., Zhou F (2014) Differential Activation Patterns of fMRI in Sleep Deprived Brain: Restoring Effects of Acupuncture. Evidence based Complementary and Alternative Medicine, Volume 2014, Article ID 465760, 7 pages.
  33. Lijun Bai*, Yin Tao, Dan Wang, Jing Wang, Chuanzhu Sun, Nongxiao Hao, Shangjie Chen*, Lixing Lao, (2014) Acupuncture induces time-dependent remodelling brain network on the stable somatosensory first ever stroke patients: combining diffusion tensor and functional MR imaging, Evidence based and Alternative Medicine, 2014, 2014: ID740480.
  34. Liu Z., Wei W., Bai L.*, Dai R., You Y., Chen S., Tian J., (2014) Exploring the patterns of acupuncture on mild cognitive impairment patients using regional homogeneity. Plos One, 9(6): e99335.
  35. Lijun Bai*, Lin Ai, Mingzhou Ding, Yong He, Lixing Lao, Fanrong Liang, (2014) Imaging Neurodegenerative Diseases: Mechanisms and Interventions, BioMed Research International, 2014: ID419317.
  36. Lijun Bai*, Richard E. Harris, Jian Kong, Lixing Lao, Vitaly Napadow, Baixiao Zhao (2014) Neurobiological Mechanisms of Acupuncture 2014, Evidence-based Complementary and Alternative Medicine, 2014, 2014: ID765068.
  37. Bai L*, Tao Y, Wang D, Wang J, Sun C, Hao N, Chen S, Lao L (2014). Acupuncture induces time dependent remodeling brain network on the stable somatosensory first ever stroke patients: combining diffusion tensor and functional MR imaging. Evidence based and Alternative Medicine, Volume 2014 (2014), Article ID 740480, 7 pages.
  38. Bai L*, Lin Ai, Mingzhou Ding, Yong He, Lixing Lao, Fanrong Liang (2014). Imaging Neurodegenerative Diseases: Mechanisms and Interventions. BioMed Research International, Article ID 419317.
  39. Zhu Y, Li Z., Bai L.*, Tao Y., Sun C., Li M., Zheng L., Zhu B., Yao J., Zhou H. and M Zhang. (2014) Loss of Microstructural Integrity in the Limbic Subcortical Networks for Acute Symptomatic Traumatic Brain Injury. BioMed Research International, Volume 2014, Article ID 548392, 7 pages.
  40. Shen Y, Bai L*, Gao Y, Cui F, Tan Z, Tao Y, Sun C, Zhou L. (2014) Depressive Symptoms in Multiple Sclerosis from an In Vivo Study with TBSS. BioMed Research International, Volume 2014, Article ID 148465, 8 pages.
  41. Xie Z., Cui F., Zou Y., and Bai L*. (2014) Acupuncture Enhances Effective Connectivity between Cerebellum and Primary Sensorimotor Cortex in Patients with Stable Recovery Stroke. Evidence Based Complementary and Alternative Medicine, Volume 2014 (2014), Article ID 603909, 9 pages.
  42. Zhang Y, Li K., Ren Y., Cui F., Xie Z., Shin J., Tan Z., Tang L., Bai L.*, and Zou Y. (2014) Acupuncture Modulates the Functional Connectivity of the Default Mode Network in Stroke Patients. Evidence Based Complementary and Alternative Medicine, Volume 2014 (2014), Article ID 765413, 7 pages.
  43. Zhang Q., Mao C., Jin J., Niu C., Bai L., Dang J.and Zhang M (2014). Laterality of gray matter loss predicted by side of limb onset in amyotrophic lateral sclerosis. BioMed Research International, Volume 2014 (2014), Article ID 473250, 11 pages.
  44. Chen S, Bai L*, et al (2013) Multivariate Granger Causality Analysis of Acupuncture Effects in Mild Cognitive Impairment patients: An fMRI study. Evidence-based Complementary and Alternative Medicine, Volume 2013 (2013), Article ID 127271
  45. You Y, Bai L*, Dai R, Cheng H, Liu Z, Wei W, Tian J* (2013) Altered Hub Configurations within Default Mode Network following Acupuncture at ST36: A Multimodal Investigation Combining fMRI and MEG. PLoS One, 8(5): e64509. (7)
  46. Chen H, Bai L*, et al. (2013) Hypothalamus-related resting brain network underlying short-term acupuncture treatment in primary hypertension. Evidence-based Complementary and Alternative Medicine, Volume 2013, Article ID 808971, 9 pages.
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