Publications ( Cited by SCI )

Synthesizing 4 ',4 ''(5 '') Di-tert-butyldibenzo 18-crown-6 Monitored by Online FTIR




作者: Fan, Juan;Yi, Chunhai;Lan, Xiaorong;Yang,Bolun
发表/完成日期: 2014-08-11
期刊名称: JOURNAL OF HETEROCYCLIC CHEMISTRY
期卷: 51(4):
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论文简介
4',4'(5') Di-tert-butyldibenzo 18-crown-6 (DTBB18C6) was successfully synthesized by S(N)2 nucleophilic substitution with 4-tert-butyl catechol as starting material. Effects of cyclization reagents, solvents, and templates were investigated. Reaction process was monitored by the real-time online FTIR to study the actual reaction route. The highest DTBB18C6 yield (above 33%) was obtained by using Cs2CO3 as the template, 2,2-diethylene glycol ditosylate as the cyclization reagent, and THF as the solvent. From the result of FTIR, four different reaction stages of DTBB18C6 synthesis process were proposed.