基本信息

姓      名: 刘   昌
单      位:西安交通大学第一附属医院肝胆外科
职      务:一附院纪委副书记;外科ICU主任
肝胆外科副主任
职      称:教授;主任医师
博士生导师(外科学、肿瘤学)
联系方式

电         话:18991232095 029-85323900
  E - mail  :eyrechang@126.com
地         址:陕西省西安市雁塔西路277号
邮政编码:710061
站点计数器
招生信息

        依托西安交通大学医学院第一附属医院浓厚的科研氛围与坚实的硬件平台,课题组致力于研究肝癌发生发展机制和临床干预治疗的研究工作,内容包括:肝癌分子水平发生机制、肝癌靶向治疗的基础与临床研究、肝硬化的早期干预、中医药在肝移植术后免疫抑制中的作用等。

       先后承担5项国家自然科学基金、1项教育部新世纪优秀人才支持计划项目以及10余项省部级科研课题,发表论文150余篇,其中SCI收录40篇,编写或参编论著7部。课题组与国内外多个学术机构有良好的合作关系。

      目前课题组在读研究生18人,其中博士研究生7人,硕士研究生11人。课题组隶属的西安交通大学医学院第一附属医院肝胆外科在西北地区具有较强的影响力,其中肝脏肿瘤年收治人数近500人次,实施手术近300余台,,基于此平台建设的肝癌标本库经过2年多的运作已初具规模。

主持人

获奖名称获奖时间备注
陕西省教育厅现代教育技术成果三等奖2003 
西安交通大学第一附属医院新医疗新技术奖

2002,2003,2004,2005

2006,2007,2008,2009,2011

 
西安市政府科学技术一等奖2003第2人完成
西安交通大学科学技术奖一等奖2003第2人完成
陕西省高等学校科学技术一等奖2003第3人完成

国家发明专利

(专利号:ZL2004 1 0026202X)

2004第3人完成
陕西省政府科学技术奖一等奖2004第4人完成
主持人简介

主持项目类别项目名称
国家自然科学基金FoxM1诱导肝癌细胞衰老的分子机制研究
国家自然科学基金可分泌Arg(9)-ARF穿膜融合肽重组慢病毒对肝癌治疗作用的实验研究
国家自然科学基金miR-375调控肝癌细胞线粒体能量代谢的作用及分子机制研究
国家自然科学基金血小板5-羟色胺与肝星状细胞激活的作用及其机制研究
国家自然科学基金NF-κB活化与移植肝冷缺血致肺损伤机制研究
教育部新世纪优秀人才支持计划项目异种移植相关研究
学术交流

1.       Zhang JY, Liu C, Zhou L, Qu K, Wang R, Tai MH, Lei Lei JC, Wu QF, Wang ZX.A review of hydrogen as a new medical therapy. Hepatogastroenterology. 2012;59(116):1026-32.
2.       Zhou L, Liu C, Meng FD, Qu K, Tian F, Tai MH, Wei JC, Wang RT.Long-term prognosis in hepatocellular carcinoma patients after hepatectomy. Asian Pac J Cancer Prev. 2012;13(2):483-486.
4.       Zhou L, Liu C, Bai JG, Wei JC, Qu K, Tian F, Tai MH, Wang RT, Meng FD.A rare giant gastrointestinal stromal tumor (GIST) of the stomach traversing the upper abdomen: a case report and literature review. World J Surg Oncol. 2012;10(1):66.
5.       Qu K, Chang HL, Liu SN, Liu C, Xu XS, Wang RT, Zhou L, Tian F, Wei JC, Tai MH, Meng FD.Prognosis and Management for Gallbladder Cancer with Hepatic Invasion: Long-term Results of 139 Patients from a Single Center in China. Asian Pac J Cancer Prev. 2012;13(3):1015-1018.
6.       Qu K, Liu C, Wang ZX, Tian F, Wei JC, Tai MH, Zhou L, Meng FD, Wang RT, Xu XS.Pyogenic liver abscesses associated with nonmetastatic colorectal cancers: An increasing problem in Eastern Asia. World J Gastroenterol. 2012;18(23):2948-2955.
7.       Jiang A, Liu C, Song Y, Liu F, Li Q, Wu Z, Yu L, Lv Y. Liver cold preservation induce lung surfactant changes and acute lung injury in rat liver transplantation. World J Gastroenterol. 2012;18(4):323-330.
8.       Kai Qu, Si-Nan Liu, Hu-Lin Chang, Chang Liu, Xin-Sen Xu, Rui-Tao Wang, Lei Zhou, Feng Tian, Ji-Chao Wei, Ming-Hui Tai, Fan-Di Meng. Gallbladder Cancer: One Subtype of Biliary Tract Cancer Which Is Current Controversy and Challenge in China. Asian Pac J Cancer Prev. 2012;13(4):1317-20.
9.       L Zhou, C Liu, F Meng, K Qu, et al. Long-term prognosis in hepatocellular carcinoma patients after hepatectomy. Asian Pac J Cancer P. 2012;13(2):483-6.
10.     J Xu, C Liu, L Zhou, F Tian, M Tai, J Wei, K Qu, et al. Distinctions between the clinicopathological factors and prognosis of alpha-fetoprotein negative and positive hepatocelluar carcinoma patients. Asian Pac J Cancer Prev. 2012;13(2):559-62.
11.     Lei Z, Chang L, Fan-Di M, Qi-Fei W, Feng T, Ming-Hui T, Ji-Chao W, Lei L, Rui-Tao W, Kai Q.Exploration on surgical-related factors influencing HCC patients prognosis. Hepatogastroenterology. 2012;59(117):1541-1543.
12.     K Qu, C Liu, Q Wu, et al. Sclerosing Cholangitis after Transcatheter Arterial Chemoembolization. Hepatol Int. 2011; 5 (s1):397.
13.     Jiang A, Liu C, Song Y, Liu F, Li Q, Wu Z, Yu L, Lv Y. NF-kB Induced the Donor Liver Cold Preservation Related Acute Lung Injury in Rat Liver Transplantation Model .PLoS One. 2011;6(9):e24960.
14.     Qu K, Liu C, Mansoor AM, Wang B, Chen J, Yu L, Lv Y.Pyogenic liver abscess as initial presentation in locally advanced right colon cancer invading the liver, gallbladder, and duodenum. Front Med. 2011;5(4):434-437.
16.     Wu QF, Liu C, Tai MH, Liu D, Lei L, Wang RT, Tian M, Lü Y.Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro. Acta Pharmacol Sin. 2010 Mar;31(3):361-366.
17.     Liu YX, Shen NY, Liu C, Lv Y. Immunosuppressive effects of emodin: an in vivo and in vitro study. Transplant Proc. 2009; 41(5):1837-1839.
18.     Liu C, Wu QF, Li QY, Liu D, Su HB, Shen NY, Tai MH, Lv Y. Mesenteric Lymphatic Ducts Ligation Decreases the Degree of Gut-Induced Lung Injury in a Portal Vein Occlusion and Reperfusion Canine Model. J Surg Res, 2009; 154 (1): 45-50.
19.     Liu C, Wu QF, Wang B, Lv Y. Combined pancreatoduodenectomy and orthotopic liver transplantation in a patient with hepatocellular carcinoma and portal vein tumor thrombus. Chinese-German J Clin Oncol, 2009; 8:734-736.
20.     Liu C, Shang YF, Zhang XF, Zhang XG, Wang B, Wu Z, Liu XM, Yu L, Ma F, Lv Y. Co-administration of grapefruit juice increases bioavailability of tacrolimus in liver transplant patients: a prospective study. European Journal of Clinical Pharmacology, 2009, 65 (9): 881-885.
21.     Qu B, Liu C, Guo L, Yang Y, Li JH, Yu L, Lv Y. The Role of Liver Transplantation in the Treatment of Hepatic Myelopathy: Case Report With Review of the Literature. TRANSPLANTATION PROCEEDINGS. 2009, 41 (5): 1987-1989.
24.     Wang ZF, Liu C, Lu Y, Dong R, Xu J, Yu L, Yao YM, Liu QG, Pan CE. Dexamethasone and dextran 40 treatment of 32 patients with severe acute pancreatitis.World J Gastroenterol. 2004, 10 (9): 1333-1336.
25.     Lu Y, Wu Z, Liu C, Wang HH. Hepatic volumetry with PhotoShop in personal computer.Hepatobiliary & Pancreatic Diseases International. 2004, 3 (1): 82-85.
26.     Wang ZF, Liu C, Lu Y, Dong R, Xu J, Yu L, Yao YM, Liu QG, Pan CE. Dexamethasone and dextran 40 treatment of 32 patients with severe acute pancreatitis.World J Gastroenterol. 2004, 10 (9): 1333-1336.
27.     Wang ZF, Liu C. Liver retransplantation: indications and outcomes. Hepatobiliary Pancreat Dis Int. 2004, 3 (2):175-178.