个人主页 - 陈 敬国
- 工作单位：西安交通大学第二附属医院耳鼻咽喉头颈外科病院
- 地址：陕西省西安市新城区西五路157号
E-mail: jing-guo.chen@mail.xjtu.edu.cn- jing-guo.chen@outlook.com
- 微博：@陈博士嗅觉味觉医学科普（点击查看我的微博·）
- 微信公众号：陈博士嗅觉味觉科普
知乎专栏：博士嗅觉味觉科普
https://www.zhihu.com/people/gu-jing-49-46
陈敬国，博士，就职于西安交通大学第二附属医院耳鼻咽喉头颈外科病院，科研秘书。
2018年获得西安交通大学医学院药理学博士学位，其中2017年至2018年在美国University of Colorado Anschutz Medical Campus耳鼻咽喉科公派留学一年，师从安舒茨医学院鼻科领域著名科学家Sue C. Kinnamon教授和Vijay Ramakrishnan副教授。
主要研究方向为慢性鼻窦炎、嗅觉味觉障碍的基础和临床研究研究。
主持获得陕西省自然科学基础研究计划项目1项，中央高校基本科研业务费资助项目1项，作为主要项目实施人员参与2项国家自然科学基金面上项目，1项国家自然科学基金青年项目，1项美国国立卫生研究院（NIH）资助项目。共发表科技论文20篇，其中SCI论文10篇。
美国化学感受与科学协会会员（Association for Chemoreception Sciences），中国病理与生理学会会员，中国药理学会会员, 全球化学感官研究联盟(Global Consortium for Chemosensory Research)成员，GCCR研究方案审核小组（SST）成员，GCCR患者协作组织成员()PAC，世界味觉嗅觉日（World Taste and Smell Day）发起人和委员会成员。
SCI期刊《Chemical Sense》审稿人。
科普专业平台“腾讯医典”认证科普专家，特约撰稿人，特约审稿专家。
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2022-06-05
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2022-01-20
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2021-09-19
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2021-05-18
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2020-09-25
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2020-08-24
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2018/12-至今 嗅觉、味觉障碍、鼻炎的基础和临床研究
2014/09-2017/08 苦味受体舒张气道平滑肌的机制研究（国家自然科学基金）
2017/08-2018/12 味觉传导分子在气道上皮的功能(美国国立卫生研究院NIH-NIDCD)
2012/09-2014/08 低剂量化疗药物促肿瘤生长的现象和机制（国家自然科学基金）
2011/12-2012/06 辛伐他丁的群体药代动力学研究
[1] Jingguo Chen，Eric D Larson，Catherine B Anderson，Pratima Agarwal，Daniel N Frank，Sue C Kinnamon，Vijay R Ramakrishnan. Expression of bitter taste receptors and solitary chemosensory cell markers in the human sinonasal cavity. Chemical senses, 2019 Sep 7;44(7):483-495. doi: 10.1093/chemse/bjz042. [Epub ahead of print]. (SCI, IF=3.235)
[2] Jingguo Chen, Nana Ping, Dong Liang, Mengyi Li, Yanni Mi, Sen Li, Lei Cao, Yongxiao Cao. The expression of bitter taste receptors in mesenteric, cerebral and omental arteries [J]. Life Sciences, 2017, 1(170), 16-24. (SCI, IF=3.234)
[3] Yan Cai, Ying Lei, Jingguo Chen, Lei Cao, Xudong Yang, Kanghuai Zhang, Yongxiao Cao. Erythromycin relaxes BALB/c mouse airway smooth muscle. Life Sciences, 2019, 221, 135-142. (SCI, IF=3.448)
[4] Jingguo Chen, Catherine Anderson, Eric Larson, Sue Kinnamon, Vijay Ramakrishnan. The distribution of SCCs markers and TAS2Rs in different locations of human sinus. The 40th annual meeting of Association for Chemoreception Sciences, Bonita Springs, Florida, USA, 2018, Apr.16-20.（会议）
[5] Jingguo Chen, Pingping Yan, Jin Wang, Yan Cai, Lei Cao, Yongxiao Cao. The Localization of TAS2R7 in Artery and Pancreas. The 39th annual meeting of Association for Chemoreception Sciences, Bonita Springs, Florida, USA, 2017. Apr.26-30.（会议）
[6] Parma V, Ohla K, Veldhuizen MG, et al (Jingguo Chen as a member of GCCR). More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis. 2020 Jun 20;bjaa041. doi: 10.1093/chemse/bjaa041. Online ahead of print..
[7] Gerkin RC, Ohla K, Veldhuizen MG,Reed DR, Niv MY, Munger SD, Parma V; GCCR Group Author (Jingguo Chen as a member of GCCR). Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms. Chem Senses. 2020 Dec 25:bjaa081. doi: 10.1093/chemse/bjaa081. Epub ahead of print. PMID: 33367502.
[8] Nana Ping, Yanni Mi, Sai Zhang, Jingguo Chen, Yongxiao Cao. H2S prevents cyclosporine A-induced vasomotor alteration in rats [J]. Cardiovascular Toxicology, 2017, 17(3):287-296. (SCI)
[9] Yingchen Zhuo, Xueqian Li, Qiaowei Zheng, Jingguo Chen, Feng WY. Estrogen enhances tumor growth and angiogenesis indirectly via mediation of bone marrow derived cells as well as directly through stimulation of tumor and endothelial cells[J]. Oncology Reports, 2018,40(4):2147-2156. (SCI).
[10] Xueqian Li, Qiaowei Zheng, Yingchen Zhuo, Jingguo Chen, Feng WY. Specificity and potency of curcumin derivative 64PH in inhibiting HepG2 human hepatocellular carcinoma cell proliferation[J]. Translational surgery, 2017,2(1):1-5.
[11] 刘海琴,尚磊,陈敬国,折宁宁,施叶雯,冯雅妮,张一彤,任晓勇.西安市小学生睡眠打鼾现状及对生活质量的影响[J].中国儿童保健杂志, 2019,27(09):1030-1033.
[12] 禚映辰, 陈敬国, 李雪倩, 郑巧伟，赵雪, 封卫毅。骨髓源性细胞在雌激素调节肿瘤血管新生中的作用及其应用[J]. 中国新药杂志, 2015, 24(5), 533-539.
[13] 李雪倩，雷海民，王鹏龙，绪扩，禚映辰，陈敬国，郑巧伟，马文斌，赵雪，许君望，封卫毅。姜黄素衍生物64PH的抗肿瘤作用[J]，2015.35(17), 1535-1539.
[14] Zhang Y, Zhu K, Xia C, Chen J, Yu C, Gao T, Yan J, Zhang H, Ren X. Multiple-Cytokine Profiling: A Novel Method for Early Prediction of the Efficacy of Sublingual Immunotherapy in Allergic Rhinitis Patients. J Inflamm Res. 2022 Jan 27;15:603-612. doi: 10.2147/JIR.S350003. PMID: 35115808; PMCID: PMC8803612.
[15]Zhu K, Xia C, Chen J, Yu C, Gao T, Yan J, Shao N, Zhu P, Sun B, Ren X, Zhang Y. Serum Soluble ST2 Correlated with Symptom Severity and Clinical Response of Sublingual Immunotherapy for House Dust Mite-Induced Allergic Rhinitis Patients. Mediators Inflamm. 2021 May 30;2021:5576596. doi: 10.1155/2021/5576596. PMID: 34194284; PMCID: PMC8181096.
(创新港)
