基本信息

 

Education:

2011-2016 Washington University in Saint Louis, Divisoin of Biological and Biomedical Science, Human and Statistical Genetics, Ph.D.

2009-2011 The Johns Hopkins University, The Bloomberg School of Public Health, Department of Epidemiology, Master of Science

2007-2009 Xi'an Jiaotong University, School of Medicine, Forensic Science, Master of Medical Science

2003-2007 Xi'an Jiaotong University, School of Life Science and Technology, Biology Engineer, Bachelor of Engineer

Work:

2016- now Xi'an Jiaotong University, School of Public Health, Department of Epidemiology and Biostatistics, Assistant Professor

联系方式

 Email:joshuaz@mail.xjtu.edu.cn

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研究领域

Research Abstract:

Current research interests in my lab include the collection and analysis of GWAS and "next generation"  sequencing data on the psychiatric disorders such as schizophrenia, bipolar disorder, nicotine dependence as well as birth defects disorders such as oral cleft and clubfoot. In additoin to the research projects collaborating with phycisians, I am also very interested at the methodological development in genetic epidemiology. Specifically,   I focused on the applications and development of network based methods applied to large scale genomics dataset. In addition, I am also working on data-driven methods and applications of modern epidemiology. 

Selected Publications:

  • Zhang T, Liu P, Zhang Y, Wang W, Lu Y, Xi M, Duan S, Guan F.Combining information from multiple bone turnover markers as diagnostic indices for osteoporosis using support vector machines.Biomarkers. 2018,15:1-7.[PMID:30442069]
  • Zhang T, Zhu L, Ni T, Liu D, Chen G, Yan Z, Lin H, Guan F, Rice JP.Voltage-gated calcium channel activity and complex related genes and schizophrenia: A systematic investigation based on Han Chinese population.J Psychiatr Res. 2018,106:99-105.[PMID:30308413]
  • Zhang T, Hou L, Chen DT, McMahon FJ, Wang JC, Rice JP.Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder.Gene. 2018,645:119-123.[PMID:29248581]
  • Tian-Xiao Zhang, Nancy L. Saccone, Laura J. Bierut and John P. Rice. Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase that contribute to the risk of nicotine dependence in European and African Americans. Brain and Behavior. 2017,7 (4) :e00651.[PMID:28413702]
  • Zhang TX, Haller G, Lin P, Alvarado DM et al. Genome-wide association study identifies new disease loci for isolated clubfoot. J Med Genet. 2014 May;51(5):334-9.[PMID:24667120]
  • Zhang TX, Xie YR and Rice JP. Application of noncollapsing methods to the gene-based association test: a comparison study using Genetic Analysis Workshop 18 data. BMC Proceedings, 2014; 8(Suppl 1):S53.[PMID:25519333]
  • Tianxiao Zhang, Ingo Ruczinski, Terri H. Beaty. Candidate pathway based analysis for cleft lip with or without cleft palate. Statistical Applications in Genetics and Molecular Biology. 11:2,2012.[PMID:22499695]
 Search "Tianxiao Zhang" on Google scholar for updated information of my publications.