Publications

33. Youkang Zhou, Qi Jiang, Yangyang Cheng, Mingyou Hu, Xin-Hua Duan, Le Liu* Photoredox Catalyzed Acylchlorination of α-CF3 Alkenes with Acyl Chloride and Application as Masked Access to b-CF3-enones, Org. Lett. 2024, 2656–2661

 

                                                            

 

32. Xiaoying Wang, Jiaxi Cai, Haixia Song, Le Liu, Xin-Hua Duan, Mingyou Hu*, Electrocatalysis-Enabled Stereoselective Synthesis of Monofluoroalkenes via Hydrodefluorination of gem-Difluoroakenes, Org. Lett. 2024, 26, 1635–1639.

 

                                                                                

 

31. Ting Xue, Cheng Ma, Le Liu, Chunhui Xiao,* Shao-Fei Ni,* Rong Zeng,* Characterization of A π–π Stacking Cocycrystal of 4-Nitrophthalonitrile Directed Toward Application in Photocatalysis. Nat.Commun. 2024,15, 2455.

                                                                   

 

30. Chonglong He, Min Wang, Yulong Wang, Lirong Zhao, Youkang Zhou, Keyuan Zhang, Shenyu Shen, Yaqiong Su, Xin-Hua Duan and Le Liu* Photoredox catalytic alkylarylation of alkynes with arylsulfonylacetate as bifunctional reagent, Sci. China Chem. 2024, 10.1007/s11426-023-1930-6

 

                                                  

 

29. Youkang Zhou, Lirong Zhao, Mingyou Hu, Xin-Hua Duan and Le Liu* Visible-Light Photoredox Catalyzed Divergent 1,2-Diacylation and Hydroacylation of Alkenes with Carboxylic Acid Anhydride. Org. Lett. 2023, 5268–5272

 

                                                                           

 

28. Ying-Jie Ma, Zi-Hang Yuan, Pin Gao, Xin-Hua Duan, Hong Xin, Le Liu and Li-Na Guo* Divergent Construction of Azaheterocycles via Alkoxyl Radical-Triggered C-C Bond Cleavage/Cyclization of N-Functionalized Acrylamides. J. Org. Chem. 2023, 9927–9940

 

                                                                      

 

27.  Yulong Wang, Shenshen Yu, Chonglong He, Youkang Zhou, Keyuan Zhang, Bin Rao, Tian Han, Yaqiong Su, Xin-Hua Duan, Le Liu*Cu(II)-mediated direct intramolecular cyclopropanation of distal olefinic acetate: access to cyclopropane-fused g-lactone, Chem. Sci. 2023, 14, 6663-6668.

 

                                                                       

 

26. Shuai Liu, Pengchen Ma, Lu Zhang, Shenyu Shen, Hong-Jie Miao, Le Liu, K. N. Houk, Xin-Hua Duan Li-Na Guo* A Cheap Metal Catalyzed Ring Expansion/Cross-Coupling Cascade: A New Route to Functionalized Medium-Sized and Macrolactones. Chem. Sci. 2023,14, 5220-5225.

 

                                                              

 

25. Dan-Ning Wang, Qi Lin, Xun Wang, Keyuan Zhang, Xin-Hua Duan, Le Liu* Visible-Light Induced Oxidative Annulation of Enamides to 2,4,5-Trisubstituted Oxazole Skeletons, Asian J. Org. Chem. 2023, 12, e202300019 (Cover Paper).

 

                                                                        

                                                                                                 

     

24. Chonglong He, Min Wang, Bowu Dong, Yaqiong Su, Xin-Hua Duan, and Le Liu*, Lone pair-π interaction induced regioselective sulfonation of ethers under light irradiation, Green. Synth. Catal. 2022, doi.org/10.1016/j.gresc.2022.12.005

 

                                                                  

 

23. Keyuan Zhang, Yulong Wang, Chonglong He, Youkang Zhou, Danning Wang, Mingyou Hu, Xin-Hua Duan, Le Liu*, Halogen bond promoted aryl migration of allylic alcohols under visible light irradiation, Org. Chem. Front. 2022, 9, 5599-5605

                                                                   

 

22. Chonglong He, Keyuan Zhang, Dan-Ning Wang, Min Wang, Yuejie Niu, Xin-Hua Duan and Le Liu* Metal-Free Visible-Light-Induced Alkylarylation of Unactivated Alkenes via Radical Addition/Truce-Smiles Rearrangement Cascade, Org. Lett.  2022, 24, 2767–2771.

                                                               

 

    

21.Keyuan Zhang, Tianbing Liang, Yulong Wang, Chonglong He, Xin-Hua Duana and Le Liu,* Oxidative thiocyanation of allylic alcohols: an easy access to allylic thiocyanates with K2S2O8 and NH4SCN, Org. Chem. Front. 20229, 966-972.

 

                                                                        

 

20. Le Liu, Xin-Hua Duan and Li-Na Guo, Recent Advance in Iminyl-Radical-Triggered CH and CC Bond Functionalization of Oxime Esters via 1,5-HAT and β-Carbon Scission, Synthesis 2021, 53, 4375-4388 (Invited paper, Cover paper)

19. Le Liu and Cristina Nevado* Diaryl Ether Formation Merging Photoredox and Nickel Catalysis, Organometallics 2021, 40, 2188-2193.

 

 

18. Li Chen, Li-Na Guo, Shuai Liu, Le Liu and Xin-Hua, Duan* Visible-light-driven palladium-catalyzed Dowd–Beckwith ring expansion/C–C bond formation cascade, Chem. Sci. 2021,12, 1791-1795.

 

 

17. Zhi-Yong Ma, Mengyang Li, Li-Na Guo, Le Liu, Dongdong Wang and Xin-Hua Duan*, Sulfonamide as Photoinduced Hydrogen-Atom Transfer Catalyst for Regioselective Alkylation of C(sp3)–H Bonds Adjacent to Heteroatoms, Org. Lett. 2021, 23, 2, 474–479

 

 

 16.   Yinan Zheng, Ying You, Qianqian Shen, Le Liu,* and Xin-Hua Duan*, Visible-Light-Induced Anti-Markovnikov Hydrosulfonation of Styrene Derivatives, Org. Chem. Front. 2020, 7, 2069-2074

 

 

 

 

15. Hong Xin, Xin-Hua Duan, Le Liu, Li-Na Guo, Metal‐free, Visible Light‐induced Selective C‐C Bond Cleavage of Cycloalkanones with Molecular OxygenChem. Eur. J.2020, 26, 11690-11694.

 

 

 

 


Before XJTU

14.      Xiang Zhang, Xiaoyu Hao, Le Liu, Anh-Tuan Pham, Javier López-Andarias, Antonio Frontera, Naomi Sakai , and Stefan Matile* Primary Anion-π Catalysis and Autocatalysis J. Am. Chem. Soc. 2018, 140, 17867-17871.

 

 

13.      Yingjie Zhao, Yoann Cotelle, Le Liu, Javier, López-Andarias, Anna-Bea Bornhof, Masaaki Akamatsu, Naomi Sakai, Stefan Matile* The Emergence of Anion-π CatalysisAcc. Chem. Res. 2018, 51, 2255-2263

 

 

12.      Xiang Zhang, Le Liu,Lopez-Andarias, Chao Wang, Naomi Sakai, Stefan Matile* Anion-π Catalysis: Focus on Nonadjacent stereocenters. Helv. Chim. Acta 2018, 101, e1700288. (co-first author)

 

 

11.      Le Liu, Yoann Cotelle, Anna-Bea Bornhof, Celine Besnard, Naomi Sakai and Stefan Matile* Anion-π Catalysis of Diels-Alder Reactions. Angew. Chem. Int. Ed. 2017, 56, 13066-13069 (Hot Paper)

10.      Le Liu, Yoann Cotelle, Vincent Lebrun, Naomi Sakai, Thomas R. Ward and Stefan Matile* Anion-π Catalysis: Bicyclic Products with Four Contiguous Stereogenic Centers from Otherwise Elusive Diastereospecific Domino Reactions on π-Acidic Surfaces. Chem. Sci. 2017, 8, 3770-3774.

 

 

9.      Le Liu and Stefan MatieAnion-π transaminase mimics. Supramol. Chem. 201729, 702-706.

8.       Le Liu; Yuann, Cotelle; Alyssa-Jennifer, Avestro; Naomi, Sakai and Stefan Matile* Asymmetric Anion-π Catalysis of Iminium/Nitroaldol Cascades to Form Cyclohexane Rings with Five Stereogenic Centers Directly on π-Acidic Surfaces. J. Am. Chem. Soc. 2016138, 7876-7879.

7.        Le Liu; Tonghuan, Zhang; Yun-Fang, Yang; Daisy Zhang-Negrerie; Xinhao Zhang, Yunfei Du;* Yun-Dong Wu* and Kang Zhao* Metal-Free Synthesis of 3Arylquinolin-2-ones from Acrylic Amides via a Highly Regioselective 1,2-Aryl Migration: An Experimental and Computational Study. J. Org. Chem. 2016, 81, 4058-4065.

 

 

6.        Le Liu; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* Hypervalent Iodine Mediated C-C Double Bond Activation:A Cascade Access to a-Keto Diacetates from Readily Available Cinnamic Acids. Synthesis, 2015, 47, 2924-2930 (Invited Paper).

 

 

5.     Le Liu; Liang, Du; Daisy Zhang-Negrerie and Yunfei Du* NIS-mediated intramolecular oxidative a-functionalization of tertiary amines: transition metal-free synthesis of 1,2-dihydro-(4H)-3,1-benzoxazin-4-one derivatives. RSC Adv. 2015, 5, 29774-29781.

 

 

4.     Le Liu; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* PhICl2 and Wet DMF: An Efficient System for Regioselective Chloroformyloxylation/a-hlorination of Alkenes/a,baturated Compounds. Org. Lett. 2014, 16, 436-439.

3.     Le Liu; Liang, Du; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* Metal-Free Tandem Oxidative Aryl Migration and C−C Bond Cleavage: Synthesis of a-Ketoamides and Esters from Acrylic Derivatives. Org. Lett. 2014, 16, 5772-5775.

 

 

2.     Le Liu; Hang, Lu; Hong, Wang; Chao, Yang; Xiang, Zhang; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* PhI(OCOCF3)2Mediated C-C Bond Formation Concomitant with a 1,2-Aryl Shift in a Metal-Free Synthesis of 3Arylquinolin-2-ones. Org. Lett. 2013, 15, 2906-2909.

1.     Le Liu; Yanfeng, Fan; Qiaoqiao, He; Yun, Zhang; Daisy Zhang-Negrerie; Jianhui, Huang,* Yunfei Du* and Kang Zhao Synthesis of Functionalized Fluorescent Indenes from Electron-Rich α-Aryl Ketonitriles. J. Org. Chem. 2012, 77, 3997-4004.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

专利

 

  1. 刘乐,张珂媛,王淡宁,梁天兵,一种取代烯基硫氰酸酯类化合物及其制备方法,授权时间:202285日,专利号:ZL202111076635.6
  2. 刘乐,贺重隆,汪民,王淡宁,张珂瑗,一种可见光促进的烯烃的芳基氟烷基化产物及其制备方法,授权时间:20221028日,专利号:ZL202111016869.1
  3. 刘乐,贺重隆,一种 α-砜基醚类化合物的制备方法,授权时间:2023728日,专利号:ZL202210862100.X
  4. 刘乐,王淡宁,王迅,一种2,4,5-三取代噁唑类化合物的制备方法,授权时间2023830日,专利号:ZL202210858291.2
  5. 杜云飞,刘乐,贺巧巧,赵康, 1,3-二腈基2-取代-1H-茚类衍生物及其制备方法,发明专利,授权时间:2014122,专利号:CN102617400A