李小军
教授 博士生导师
国家级青年人才
西安交通大学青年拔尖人才 A类
个人主页 - 李 小军
2022: 第45届耳鼻喉科国际会议(ARO) 旅行奖
2021: 约翰霍普金斯大学青年科学家奖 (W. Barry Wood Jr. Award)
2021: 第44届耳鼻喉科国际会议(ARO)旅行奖
2020: 第43届耳鼻喉科国际会议(ARO)旅行奖
2015: 中国科学院院长优秀奖学金
中国西部科技创新港泓润楼（19号楼）
西安交通大学前沿科学技术研究院
E-mail: lixiaojun4183@xjtu.edu.cn
李小军，国家级青年人才，西安交通大学前沿科学技术研究院教授、博士生导师、西安交通大学青年拔尖人才。2016.02至2023.02在约翰霍普金斯大学神经科学系从事博士后，主要研究方向为感音神经性耳聋与耳蜗毛细胞再生。主要揭示了调控哺乳动物支持细胞可塑性的分子“开关”，发现了促进毛细胞再生的新策略，实现了支持细胞重编程的可视化，并完善了毛细胞再生的调控网络。文章以第一作者身份发表在PNAS (2020) 、Science Advances (2022)、EMBO reports (2023)，Journal of Virology(2013, 2015)杂志上。曾获得2021年约翰霍普金斯大学青年科学家奖，2020至2022年连续三次获得耳鼻喉科最大国际会议(ARO)旅行奖。曾主持一项国家自然科学基金青年项目。目前课题组经费充足，在创新港19号楼和21号楼均有独立实验室。
2010.09~2015.07: 中国科学院武汉病毒研究所 博士
2006.09~2010.07: 南昌大学 本科
| 2023.10-至今: | 西安交通大学 | 第一附属医院、口腔医院 | 特聘教授（双聘） |
| 2023.03-至今: | 西安交通大学 | 前沿科学技术研究院 | 教授 |
| 2016.02-2023.02: | Johns Hopkins University | 神经科学系 | 博士后 |
| 2015.09-2016.02: | 中国科学院武汉病毒研究所 | 分子病毒学国家重点实验室 | 助理研究员 |
| 2014.05-2015.04: | Inserm(法国国家健康与医学研究院) | 访问学者 |
2024.01-2029.12：西安交通大学青年拔尖人才项目A类，200万元，主持
2024.01-2026.12：国家自然科学基金优秀青年科学基金项目（海外）,100万元，主持
2024.01-2026.12：陕西省重点项目，编号2024JC-ZDXM-43，20万元，主持
2017.01-2019.12：国家自然科学基金青年项目，编号31600145，21万元，主持。
2023: 第九届中国听觉科学大会
2022: PNC Neuroscience Seminar Series-学术报告
2022: 第45届耳鼻喉科国际会议(ARO)-学术报告
2021: 约翰霍普金斯大学神经科学系retreat- 学术报告
2021: 第44届耳鼻喉科国际会议(ARO)-展报
2020: 第43届耳鼻喉科国际会议(ARO)-学术报告
1. Xiao-Jun Li, Charles Morgan, Prathamesh Nadar Ponniah, Waldemar Kolanus, and Angelika Doetzlhofer (2023). TRIM71 reactivation enhances the mitotic and hair cell-forming capacity of cochlear-supporting cells. EMBO Reports.e56562
2. Xiao-Jun Li, Charles Morgan, Loyal A. Goff, Angelika Doetzlhofer (2022). Follistatin promotes LIN28B mediated supporting cell reprogramming and hair cell regeneration in the murine. Science Advances. 8, eabj7651.
3. Xiao-Jun Li, Doetzlhofer A (2020). LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling. Proc Natl Acad Sci U S A. 117(36):22225-22236.
4. Xiao-Jun Li, XJ Liu, B Yang, YR Fu, F. Zhao, ZZ Shen, LF Miao, S Rayner, SChavanas, H Zhu, WJ Britt, QY Tang, MA McVoy, and MH Luo (2015). Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells. J Virol. 89(13):6792-6804.
5. Pan X*, Xiao-Jun Li*, (*共同第一作者) Liu XJ, Yuan H, Li JF, Duan YL, Ye HQ, Fu YR, Qiao GH, Wu CC, Yang B, Tian XH, Hu KH, Miao LF, Chen XL, Zheng J, Rayner S, Schwartz PH, Britt WJ, Xu J, Luo MH (2013). Later Passage Neural Progenitor Cells from Neonatal Brain Are More Permissive for Human Cytomegalovirus Infection. J Virol. 87(20):10968-10979.
6. Phan Q. Duy, Stefan C. Weise, Claudia Marini, Xiao-Jun Li, Dan Liang, Peter J. Dahl, Shaojie Ma 1, Ana Spajic, Weilai Dong, Jane Juusola, Emre Kiziltug, Adam J. Kundishora, Sunil Kounda, Maysam Z. Pedram, Lucia A. Torres-Fernández, Kristian Händler, Elena De Domenico, Matthias Becker, Thomas Ulas, Stefan A. Juranek, Elisa Cuevas, Le Thi Hao, Bettina Jux, André M. M. Sousa, Fuchen Liu, Suel-Kee Kim, Mingfeng Li, Yiying Yang, Yutaka Takeo, Alvaro Duque, Carol Nelson-Williams, Yonghyun Ha, Kartiga Selvaganesan, Stephanie M. Robert, Amrita K. Singh, Garrett Allington, Charuta G. Furey, Andrew T. Timberlake, Benjamin C. Reeves, Hannah Smith, Ashley Dunbar, Tyrone DeSpenza Jr., June Goto, Arnaud Marlier, Andres Moreno-De-Luca, Xin Yu, William E. Butler, Bob S. Carter, Evelyn M. R. Lake, R. Todd Constable, Pasko Rakic, Haifan Lin, Engin Deniz, Helene Benveniste, Nikhil S. Malvankar, Juvianee I. Estrada-Veras, Christopher A. Walsh, Seth L. Alper, Joachim L. Schultze, Katrin Paeschke, Angelika Doetzlhofer, F. Gregory Wulczyn, Sheng Chih Jin, Richard P. Lifton, Nenad Sestan, Waldemar Kolanus and Kristopher T. Kahle (2022). Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus. Nature Neuroscience. 10.1038/s41593-022-01043-3.
7. Yue-Peng Zhou, Meng-Jie Mei, Xian-Zhang Wang, Sheng-Nan Huang, Lin Chen, Ming Zhang, Xin-Yan Li, Hai-Bin Qin , Xiao Dong, Shuang Cheng, Le Wen, Bo Yang, Xue-Fang An, Ao-Di He, Bing Zhang, Wen-Bo Zeng, Xiao-Jun Li, Youming Lu, Hong-Chuang Li, Haidong Li, Wei-Guo Zou, Alec J Redwood, Simon Rayner, Han Cheng, Michael A McVoy, Qiyi Tang, William J Britt, Xin Zhou, Xuan Jiang, Min-Hua Luo.(2022). A congenital CMV infection model for follow-up studies of neurodevelopmental disorders, neuroimaging abnormalities, and treatment. JCI insight. 7(1):e152551.
8. Evsen L, Xiao-Jun Li, Zhang S, Razin S, Doetzlhofer A (2020). Let-7 miRNAs inhibit CHD7 expression and control auditory-sensory progenitor cell behavior in the developing inner ear. Development. 147(15):dev183384.
9. Wu CC, Jiang X, Wang XZ, Liu XJ, Xiao-Jun Li, Yang B, Ye HQ, Harwardt T, Jiang M, Xia HM, Wang W, Britt WJ, Paulus C, Nevels M, Luo MH (2018). Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus. J Virol. 92(17):e00340-18.
10. Liu XJ, Yang B, Huang SN, Wu CC, Xiao-Jun Li, Cheng S, Jiang X, Hu F, Ming YZ, Nevels M, Britt WJ, Rayner S, Tang Q, Zeng WB, Zhao F, Luo MH (2017). Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase. PloS Pathog. 13(7):e1006542.
11. Rolland M, Xiao-Jun Li, Sellier Y, Martin H, Perez-Berezo T, Rauwel B, Benchoua A, Bessières B, Aziza J, Cenac N, Luo M, Casper C, Peschanski M, Gonzalez-Dunia D, Leruez-Ville M, Davrinche C, Chavanas S (2016). PPARγ Is Activated during Congenital Cytomegalovirus Infection and Inhibits Neuronogenesis from Human Neural Stem Cells. PloS Pathog. 12(4):e1005547. (The week's Featured Research Article).
12. Fu YR, Liu XJ, Xiao-Jun Li, Shen ZZ, Yang B, Wu CC, Li JF, Miao LF, Ye HQ, Qiao GH, Rayner S, Chavanas S, Davrinche C, Britt WJ, Tang Q, McVoy M, Mocarski E, Luo MH (2014). MicroRNA miR-21 Attenuates Human Cytomegalovirus Replication in Neural Cells by Targeting Cdc25a. J Virol. 89(2):1070-1082.
(创新港)
