科研项目
项目编号 项目名称 项目来源 起讫时间 承担角色 项目类别
No. 81371288 脑靶向PI3Kgamma抑制剂纳米缓释载体对缺血性脑卒中的保护作用研究 国家自然科学基金项目2014-1~负责人纵向项目
No. 2013KW32-04 常见肿瘤治疗方法及作用机理研究—PI3K抑制剂纳米新剂型及其靶向抗肿瘤研究 其他2013-1~负责人横向项目
No. 81172170 高肿瘤组织渗透性多功能靶向纳米载药系统的构建及其在结直肠癌治疗中的应用研究 国家自然科学基金项目2012-1~负责人纵向项目
No. 31101266 硫酸酯壳聚糖对胰岛β细胞氧化损伤的保护作用及其机制研究 国家自然科学基金项目2012-1~负责人纵向项目
20110546 3-羟基丁酸的生物活性研究 其他2011-1~负责人横向项目
No. 08143011 硫酸酯壳聚糖对氧化应激诱导胰岛细胞损伤的抑制作用及机制 其他2011-1~骨干成员纵向项目
No. 30801059 基于PHB 生物聚酯纳米微球的MHC-II 限制性肿瘤排斥抗原筛选系统的建立及其免疫活性研究 国家自然科学基金项目2008-1~负责人纵向项目
No. 200806981053 生物可降解羟基丁酸-羟基己酸共聚酯与神经干细胞生物相容性的研究 国家教育部项目2008-1~负责人横向项目
共有8条记录 共有1页面 每页面显示 条记录 页索引: 1 链接到第 页面
学术论文

 

1.      Lin H, Lei Y, Zhang B, Dai Z, Lu XY*. Common variants of HTR1A and SLC6A4 confer the increasing risk of Schizophrenia susceptibility a population-based association and epistasis analysis, 1552-4841 Am J Med Genet B Neuropsychiatr Genet, 2015, 168(8): 749-755.

 

2.      Xiao-yun Lu *, Ming-Chuan Li, Xin-Liang Zhu, Fan Fan, Lei-Lei Wang, Jian-Gang Ma. Microbial synthesized biodegradable PHBHHxPEG hybrid copolymer as an efficient intra- cellular delivery nanocarrier for kinase inhibitor. BMC Biotechnology 2014, 14:4

 

3.      Hai-xia Lu, Zhi-qian Yang, Qian Jiao, Yuan-yuan Wang, Li Wang, Peng-bo Yang, Xin-lin Chen, Peng-bo Zhang, Peng Wang, Ming-xia Chen, Xiao-yun Lu*, Yong Liu*. Low concentration of serum helps to maintain the characteristics of NSCs/NPCs on alkali-treated PHBHHx film in vitro. Neurol Res. 2014, 36(3):207-14.

 

4.      Fan Fan, Lu Xiao-yun*, Ma Jian-Gang. Phosphatidylinositol 3-Kinase γ/δ in Inflammatory Diseases. Chinese Journal of Biochemistry and Molecular Biology. 2014, 30(10): 963-972.

 

5.      Fan Fan, Lu Xiao-yun*, REN Kai, MA Jian-gang. Study of entrapment and sustained release of hydrophobic drugs from PHBHHx-PEG NPs. Chinese Journal of Biomedical Engineering. 2014, 23(2):66-73.

 

6.      Xiao-yun Lu, Hui Guo, Lijun Sun, Liyu Zhang, Yali Zhang*. Protective effects of sulfated chitooligosaccharides with different degrees of substitution in MIN6 cells. International Journal of Biological Macromolecules, 2013(52): 92-98.

 

7.      Xiao-yun Lu, Xiaoyan Mo, Hui Guo, Yali Zhang*. Sulfation modification and anticoagulant activity of the polysaccharides obtained from persimmon (Diospyros kaki L.) fruits, International Journal of Biological Macromolecules, 2012(51): 1189-1195.

 

8.      Ming-Chuan Li, Qian-Qian Liu, Xiao-yun Lu*, Ya-Li Zhang and Lei-Lei Wang. Heterologous expression of human costimulatory molecule B7-2 and construction of B7-2 immobilized polyhydroxyalkanoate nanoparticles for use as an immune activation agent. BMC Biotechnology. 2012, 12(1): 43

 

9.  Zhang Yali, Lu Xiao-yun*, Qian-qian Liu, Ming-chuan Li, Zhi-qian Yang and Jian-gang Ma. Production and Characterization of Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)-Poly(ethy- lene glycol) hybird copolymer with adjustable Molecular Weight. Chinese Journal of Polymer Science. 2012, 30, 1: 101-111.

 

10.  Xiao-yun Lu, Hui Guo, Ya-Li Zhang*. Protective effects of sulfated chitooligosaccharides against hydrogen peroxide-induced damage in MIN6 cells, International Journal of Biological Macromolecules, 2012, 82:50-58.

 

11.  Xiao-yun Lu, Elisa Ciraolo, Rachele Stefenia, Guo-Qiang Chen, Yali Zhang, Emilio Hirsch. Sustained release of PI3K inhibitor from PHA nanoparticles and in vitro growth inhibition of cancer cell lines. Applied Microbiology and Biotechnology. 2011, 89: 1423-1433.

 

12.  Margherita Guasconi♯, Xiao-yun Lu, Alberto Massarotti, Antonio Caldarellia Elisa Ciraolo, Gian Cesare Tron, Emilio Hirsch, Giovanni Sorba and Tracey Pirali. Groebke-Blackburn-Bienaymé multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors. Organic & Biomolecular Chemistry. 2011, 9(11): 4144-4149.

 

13.  Lu, Xiao-yun, Wu, Daocheng, Li, Zhengjun, Chen, Guoqiang. Polymer nanoparticles. Progress in Molecular Biology and Translational Science, 2011, 104:299-323.

 

14.  Xiao-yun Lu, Yali Zhang, Liang Wang. Preparation and in vitro Drug-Release Behavior of 5-Fluorouracil-Loaded Poly(hydroxybutyrate-co-hydroxyhexanoate) Nano/microparticles. Journal of Applied Polymer Science. 2010, 116, 2944–2950.

 

15.  Xiao-yun Lu, Leilei Wang, Zhiqian Yang, Haixia Lu*. Strategies of polyhydroxyalkanoates modification for the medical application in neural regeneration/nerve tissue engineering. Advances in Bioscience and Biotechnology, 2013, 4, 731-740.

 

16.  Junyu Zhang, Qian Cao, Shaowu Li, Xiao-yun Lu, Yongxi Zhao, Ji-Song Guan, Jin-Chun Chen, Qiong Wu, Guo-Qiang Chen. 3-Hydroxybutyrate methyl ester as a potential drug against Alzheimer’s disease via mitochondria protection mechanism. Biomaterials, 2013, 34: 7552-7562.

 

17.  Yali Zhang, Xiao-yun Lu, Zhongbin Fu, Zibao Wang, Jianbao Zhang. Sulphated modification of a polysaccharide obtained from fresh persimmon (Diospyros kaki L.) fruit and antioxidant activities of the sulphated derivatives. Food Chemistry, 2011, 127:1084–1090.

 

18.  Elisa Ciraolo, Fulvio Morello, Robin M. Hobbs, Frieder Wolf, Romina Marone, Manuela Iezzi, Xiao-yun Lu, Giulio Mengozzi, Fiorella Altruda, Giovanni Sorba, Kaomei Guan, Pier Paolo Pandolfi, Matthias P. Wymann, Emilio Hirsch. Essential role of the p110β subunit of phosphoinositide 3-OH kinase in male fertility. Molecular Biology of the Cell. 2010, 21: 704-711.

 

19.  Yali Zhang, Xiao-yun Lu, Yuning Zhang, Liguo Qin, Jianbao Zhang. Sulfated modification and immunomodulatory activity of water-soluble polysaccharides derived from fresh Chinese persimmon fruit Export Find Similar. International Journal of Biological Macromolecules. 2010, 46: 67-71.

 

20.  Yali Zhang, Jianbao Zhang, Xiaoyan Mo, Xiao-yun Lu, Yuning Zhang, Liguo Qin. Modification, characterization and structure-anticoagulant activity relationships of persimmon polysaccharides. Carbohydrate Polymers 2010, 82: 515-520.

 

21.  Laura Braccini, Elisa Ciraolo, Fulvio Morello, Xiao-yun Lu and Emilio Hirsch. PI3K signaling: a crossroads of metabolic regulation. Expert Review of Endocrinology & Metabolism. 2009, 4: 349-357.

 

22.  Lijun Sun, Jianbao Zhang, Xiao-yun Lu, Liyu Zhang, Yali Zhang*. Evaluation to the antioxidant activity of total flavonoids extract from persimmon ( Diospyros kaki L.) leaves. Food and Chemical Toxicology. 2011, 49: 2689–2696.

 

 

会议论文

   1.   Peng Wenyu, Ma Jiangang, Lu Xiaoyun, Xie Yanzhao. The effect of standard cell culture encironment on cellular electromagnetic effects study. ASIAEM2015. 2015. Aug. 2-7, Korea.

   2.   Lu Xiaoyun, Li Kejie, Peng Wenyu, Xie Yanzhao. An Incubator Combined with TEM-cell for Cellular Electromagnetic Effects Study. AMEREM2014. 2014. Jul. 27-31, USA.

   3.   Hai-Xia Lu, Xiao-yun Lu*, Zhiqian Yang, Yuanyuan Wang , Qian Jiao, Li Wang, Yong Liu. Cyto-compatibility of NaOH treated PHBHHx film with rat neural stem cell. 2nd international Conference on Tissue Science and Regenerative Medicine. 2013 Aug. 26-28, USA.

   4.   Ming-Chuan Li, Ya-Li Zhang, Lei-Lei Wang, Xiao-yun Lu*. Construction of a PHA-based Tumor-Penetrating Drug Delivery Nano-System. International Symposium on Biopolymers. 2012 Oct. 7-10. Australia.

   5.  Haixia Lu, Zhiqian Yang, Xiao-yun Lu*, Qian Jiao, Xinlin Chen, Yuanyuan Wang. Biocompatibility and Bioactivity of PHBHHx as Supporting Material for NSCs Transplantation. International Symposium on Biopolymers. 2012 Oct. 7-10. Australia.

   6.   Xiao-Yun Lu, Rachele Stefenia, Ya-Li Zhang, Elisa Ciraolo, Emilio Hirsch. Sustained release of PI3K inhibitor from PHA nanoparticles and in vitro growth inhibition of cancer cell lines. International Symposium on Biopolymers. 2010 Oct. 3-7. Germany.

   7.  吕海侠,卢晓云,杨志倩,李明川,刘勇.PHBHHx膜性材料的表面改性及其与大鼠胚胎神经干细胞的组织相容性研究.2011年神经生物学年会,2011.0,河南郑州.

版权所有:西安交通大学 站点设计:网络信息中心 陕ICP备05001571号 IPhone版本下载 IPhone版本下载    Android版本下载 Android版本下载
欢迎您访问我们的网站,您是第 位访客
推荐分辨率1024*768以上 推荐浏览器IE7 Fifefox 以上