Main Publication

 Liu ZQ, Ren JJ, Zhao JL, Zang J, Long QF, Du JJ, Jia XT, Gu NB, Di ZL, Qian YH*, Li SZ* MicroRNA-144 represses gliomas progression and elevates susceptibility to 

     Temozolomide by targeting CAV2 and FGF7. Sci Rep. 2020,10(1):4155 (*Corresponding author).

Wang M, Zong HF, Chang KW, Han H, Yasir Rizvi M, Iffat Neha S, Li ZY, Yang WN, Qian YH*. 5-HT1AR alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice. Int Immunopharmacol. 2020, 82:106354(*Corresponding author).

Ke-Wei Chang, Hang-Fan Zong, Meng Wang, Mohammad Yasir Rizvi, Saema Iffat Neha, Wei-Na Yang, Sheng-Feng Ji , Yan-Bing Ma, Yi-Hua Qian*. PNU282987 alleviates Aβ-induced anxiety and depressive-like behaviors through upregulation of α7nAChR by ERK-serotonin receptors pathway. Neurosci Lett. 2020, 731:135118 (*Corresponding author).

97. Gui-hong Zhang, Krishna Dilip Murthy, Rahmawati Binti Pare, Yi-hua Qian*. Protective effect of Tβ4 on central nervous system tissues and its developmental prospects. European Journal of Inflammation. 2020, 18: 1-11.(*Corresponding author).


Gu N, Wang X, Di Z, Xiong J, Ma Y, Yan Y, Qian Y*, Zhang Q, Yu J. Silencing lncRNA FOXD2-AS1 inhibits proliferation, migration, invasion and drug 

      resistance of drug-resistant glioma cells and promotes their apoptosis via microRNA-98-5p/CPEB4 axis. Aging (US). 2019 Nov 26;11(22):10266-

      10283. (*Corresponding author)


Qiankun Quan, Yihua Qian*, Xi Li, Ming Li. CDK5 Participates in Amyloid-β Production by Regulating PPARγ Phosphorylation in Primary Rat

      Hippocampal Neurons. J Alzheimers Dis. 2019 Aug 6. doi: 10.3233/JAD-190026. (*Corresponding author)


Qiankun Quan, Yihua Qian*, Xi Li, Ming Li. Pioglitazone Reduces β Amyloid Levels via Inhibition of PPARγ Phosphorylation in a Neuronal Model of

      Alzheimer's Disease.Front Aging Neurosci. 2019 Jul 17;11:178. doi: 10.3389/fnagi.2019.00178. eCollection 2019. (*Corresponding author)


 Gu N, Wang J, Di Z, Liu Z, Jia X, Yan Y, Chen X, Zhang Q, Qian Y*.The Effects of Intelectin-1 on Antioxidant and Angiogenesis in HUVECs Exposed to 

      Oxygen Glucose Deprivation.Front Neurol. 2019 Apr 16;10:383. doi: 10.3389/fneur.2019.00383. eCollection 2019. (*Corresponding author)


Ma KG, Qian YH*. Alpha 7 nicotinic acetylcholine receptor and its effects on Alzheimer's disease. Neuropeptides. 2019, 73: 96-

      106(*Corresponding author


Yang W, Zhang J, Shi L, Ji S, Yang X, Zhai W, Zong H, Qian Y*. Protective effects of tanshinone IIA on SH-SY5Y cells against oAβ1-42-induced apoptosis

       due to prevention of endoplasmic reticulum stress. Int J Biochem Cell Biol. 2019,107:82-91. (*Corresponding author


Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH*. Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.Neurochem Int. 2018 ;120:238-250.(*Corresponding author) 


Kai-Ge Ma, Jia Lv, Wei-Na Yang, Ke-Wei Chang, Xiao-Dan Hu, Li-Li Shi, Wan-Ying Zhai, Hang-Fan Zong, Yi-Hua Qian*. The p38 mitogen activated protein kinase regulates β-amyloid protein internalization through theα7 nicotinic acetylcholine receptor in mouse brain. Brain Research Bulletin, 2018,13741-52 (*Corresponding author)


Naibing Gu, Yaru Dong, Ye Tian, Zhengli Di, Zhiqin Liu, Mingze Chang, Xiaotao Jia, Yihua Qian*,Weiping Zhang. Anti-apoptotic and angiogenic effects of intelectin-1 in rat cerebral ischemia. Brain Research Bulletin, 2017, 130:27-35. (*Corresponding author)


Zhang L, Xiao X, An H, Wang J, Ma Y, Qian YH*. Inhibition of CCR7 promotes NF-κB-dependent apoptosis and suppresses epithelial-mesenchymal

     transition in non-small cell lung cancer. Oncol Rep. 2017, 37(5):2913-2919. (*Corresponding author)


Wu SD, Xia F, Lin XM, Duan KL, Wang F, Lu QL, Cao H, Qian YH*, Shi M*. Ginsenoside-Rd Promotes Neurite Outgrowth of PC12 Cells through

      MAPK/ERK- and PI3K/AKT-Dependent Pathways. Int J Mol Sci. 2016 Jan 29;17(2). pii: E177. (*Corresponding authors


Ma KG, Lv J, Hu XD, Shi LL, Chang KW, Chen XL, Qian YH*, Yang WN*, Qu QM*. The p38 mitogen-activated protein kinase signaling pathway is

     involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain. Int J Biochem Cell Biol.

     2016 ,76:75-86. (*Corresponding authors


Chang Liu, YouxuanWu, ShuaZha, Mengping Liua, Ying Wang, Guangde Yang, Kaige Ma, Yulang Fei, Yaojie Zhang, Xiaodan Hu, Weina Yang*, Yihua Qian*. Treatment effects of tanshinone IIA against intracerebroventricular streptozotocininduced memory deficits inmice. Brain Res. 2016,1631:137-146 (*Corresponding authors


Yang WN, Ma KG, *Qian YH, Zhang JS, Feng GF, Shi LL, Zhang ZC, Liu ZH. Mitogen-activated protein kinase signaling pathways promote low-density lipoprotein receptor-related protein 1-mediated internalization of beta-amyloid protein in primary cortical neurons. Int J Biochem Cell Biol. 2015, 64:252-264 (*Corresponding authors)
Li-Tao Yang, Ning Wang , Zeng-Xian Li , Cui Liu, Xin He, Jian-Fei Zhang , Hua Han, You-Feng Wen , *Yi-Hua Qian , *Huan-Jiu Xi. Study on adult physique with Heath-Carter anthropometric somatotype in Han of Xi’an, China . Anat Sci Int.,2016,  91(2):180-187 (*Corresponding authors)

Songdi Wu, Ningning Li, Feng Xia, Kastytis Sidlauskas, Xuemei Lin, Yihua Qian, Wei Gao and Qinlu Zhang. Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg Syndrome): case report and literature review.BMC Neurol. 2014, 14(1):231(Page1-4).


Weina Yang, Lili Shi, Lianji Chen, Bingyi Zhang, Kaige Ma, Yong Liu, *Yihua Qian. Protective effects of perindopril on D-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampusof mice. Brain Research Bulletin, 2014, 109: 46-53 (*Corresponding authors 


Yang WN, Ma KG, Chen XL, Shi LL, Bu G, Hu XD, Han H, Liu Y, *Qian YH. Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells. Neuroscience. 2014, 278: 276-290. (*Corresponding authors)


Wei-Na Yang,Xiao-Dan Hu, Hua Han, Li-Li Shi, Gai-Feng Feng,Yong Liu, *Yi-Hua Qian. The effects of valsartan on cognitive deficits induced by aluminium trichloride and D-galactose in mice. Neurological Research, 2014,36(7):651-658(*Corresponding authors)


Wei-Na Yang, Hua Han, Xiao-Dan Hu Gai-Feng Feng,*Yi-Hua Qian. The effects of perindopril on cognitive impairment induced by D-galactose and aluminum trichloride via inhibition of acetylcholinesterase activity and oxidative stress. Pharmacology, Biochemistry and Behavior, 2013 , 114-115: 31-36*Corresponding authors


Qian YH, Xiao Q, Xu J.The protective effects of tanshinone IIA on β-amyloid protein (1-42)-induced cytotoxicity via activation of the Bcl-xL pathway in neuron.Brain Res Bull. 2012, 88(4): 354-358


Shi LL, Yang WN, Chen XL, Zhang JS, Yang PB, Hu XD, Han H, *Qian YH, *Liu Y.The protective effects of tanshinone IIA on neurotoxicity induced by β-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons.Neurochem Int. 201261(2): 227-235 *Corresponding authors


He X, Zhang JF, Li ZX, Liu C, Yang LT, Wang N, Han H, *Qian YH, Wen YF, *Xi HJ The traits of five types of tongue movement in Han of Shaanxi, China. Anat Sci Int. 2012,87(4):81-86.*Corresponding authors)


Yi-Hua Qian, Qingli Xiao, Hong Chen, Jan Xu. Dexamethasone Inhibits Camptothecin-Induced Apoptosis in C6-Glioma via Activation of Stat5/Bcl-xL Pathway. BBA - Molecular Cell Research, 2009, 1793(5):764-71


Qian YH, Han H, Hu XD Shi LL. Protective effect of ginsenoside Rb1 on amyloid protein(1-42)-induced neurotoxicity in cortical neurons. Neurol Res, 2009, 31(7): 663-667.


Lu HX, Li MJ, Song TS, Qian YH, Xiao XL, Chen XL, Zhang PB, Feng XS, Terence P, Liu Y. Retrovirus delivered neurotrophin-3 promotes survival, proliferation and neuronal differentiation of human fetal neural stem cells in vitro. BRAIN RESEARCH BULLETIN, 2008,77(4): 158-164


Jie-Hua Xu, Hai-Tao Hu, Yong Liu, Yi-Hua Qian, Zhao-Hui Liu,Qing-Rong Tan, Zhang-Jin Zhang.Neuroprotective effects of ebselen are associated with the regulation of Bcl-2 and Bax proteins in cultured mouse cortical neurons. Neuroscience Letters, 2006, 399: 210–214


Zhang-Jin Zhang, Yi-Hua Qian, Hai-Tao Hu, Jie Yang, Guang-De Yang.The herbal medicine Dipsacus asper Wall extract reduces the cognitive deficits and overexpression of β-amyloid protein induced by aluminum exposure. Life Sciences ,2003,73(19): 2443-2454


Qian YH, Liu Y, Hu HT, Ren HM, Chen XL, Xu JH.The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by b-amyloid protein 25-35.Anatomical Science International,2002,77(3):196-200


 Wu SD, Xia F, Lin XM, Duan KL, Wang F, Lu QL, Cao H, Qian YH*, Shi M*. Ginsenoside-Rd Promotes Neurite Outgrowth of PC12 Cells through MAPK/ERK- and PI3K/AKT-Dependent Pathways. Int J Mol Sci. 2016 Jan 29;17(2). pii: E177. (*Corresponding authors)