Main Publication

Qiankun Quan, Yihua Qian*, Xi Li, Ming Li. CDK5 Participates in Amyloid-β Production by Regulating PPARγ Phosphorylation in Primary Rat

      Hippocampal Neurons. J Alzheimers Dis. 2019 Aug 6. doi: 10.3233/JAD-190026. (*Corresponding author)

 

Qiankun Quan, Yihua Qian*, Xi Li, Ming Li. Pioglitazone Reduces β Amyloid Levels via Inhibition of PPARγ Phosphorylation in a Neuronal Model of

      Alzheimer's Disease.Front Aging Neurosci. 2019 Jul 17;11:178. doi: 10.3389/fnagi.2019.00178. eCollection 2019. (*Corresponding author)

 

 Gu N, Wang J, Di Z, Liu Z, Jia X, Yan Y, Chen X, Zhang Q, Qian Y*.The Effects of Intelectin-1 on Antioxidant and Angiogenesis in HUVECs Exposed to 

      Oxygen Glucose Deprivation.Front Neurol. 2019 Apr 16;10:383. doi: 10.3389/fneur.2019.00383. eCollection 2019. (*Corresponding author)

 

Ma KG, Qian YH*. Alpha 7 nicotinic acetylcholine receptor and its effects on Alzheimer's disease. Neuropeptides. 2019, 73: 96-

      106(*Corresponding author

 

Yang W, Zhang J, Shi L, Ji S, Yang X, Zhai W, Zong H, Qian Y*. Protective effects of tanshinone IIA on SH-SY5Y cells against oAβ1-42-induced apoptosis

       due to prevention of endoplasmic reticulum stress. Int J Biochem Cell Biol. 2019,107:82-91. (*Corresponding author

 

Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH*. Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.Neurochem Int. 2018 ;120:238-250.(*Corresponding author) 

 

Kai-Ge Ma, Jia Lv, Wei-Na Yang, Ke-Wei Chang, Xiao-Dan Hu, Li-Li Shi, Wan-Ying Zhai, Hang-Fan Zong, Yi-Hua Qian*. The p38 mitogen activated protein kinase regulates β-amyloid protein internalization through theα7 nicotinic acetylcholine receptor in mouse brain. Brain Research Bulletin, 2018,13741-52 (*Corresponding author)

 

Naibing Gu, Yaru Dong, Ye Tian, Zhengli Di, Zhiqin Liu, Mingze Chang, Xiaotao Jia, Yihua Qian*,Weiping Zhang. Anti-apoptotic and angiogenic effects of intelectin-1 in rat cerebral ischemia. Brain Research Bulletin, 2017, 130:27-35. (*Corresponding author)

 

Zhang L, Xiao X, An H, Wang J, Ma Y, Qian YH*. Inhibition of CCR7 promotes NF-κB-dependent apoptosis and suppresses epithelial-mesenchymal

     transition in non-small cell lung cancer. Oncol Rep. 2017, 37(5):2913-2919. (*Corresponding author)

 

Wu SD, Xia F, Lin XM, Duan KL, Wang F, Lu QL, Cao H, Qian YH*, Shi M*. Ginsenoside-Rd Promotes Neurite Outgrowth of PC12 Cells through

      MAPK/ERK- and PI3K/AKT-Dependent Pathways. Int J Mol Sci. 2016 Jan 29;17(2). pii: E177. (*Corresponding authors

 

Ma KG, Lv J, Hu XD, Shi LL, Chang KW, Chen XL, Qian YH*, Yang WN*, Qu QM*. The p38 mitogen-activated protein kinase signaling pathway is

     involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain. Int J Biochem Cell Biol.

     2016 ,76:75-86. (*Corresponding authors

 

Chang Liu, YouxuanWu, ShuaZha, Mengping Liua, Ying Wang, Guangde Yang, Kaige Ma, Yulang Fei, Yaojie Zhang, Xiaodan Hu, Weina Yang*, Yihua Qian*. Treatment effects of tanshinone IIA against intracerebroventricular streptozotocininduced memory deficits inmice. Brain Res. 2016,1631:137-146 (*Corresponding authors

 

Yang WN, Ma KG, *Qian YH, Zhang JS, Feng GF, Shi LL, Zhang ZC, Liu ZH. Mitogen-activated protein kinase signaling pathways promote low-density lipoprotein receptor-related protein 1-mediated internalization of beta-amyloid protein in primary cortical neurons. Int J Biochem Cell Biol. 2015, 64:252-264 (*Corresponding authors)
 
Li-Tao Yang, Ning Wang , Zeng-Xian Li , Cui Liu, Xin He, Jian-Fei Zhang , Hua Han, You-Feng Wen , *Yi-Hua Qian , *Huan-Jiu Xi. Study on adult physique with Heath-Carter anthropometric somatotype in Han of Xi’an, China . Anat Sci Int.,2016,  91(2):180-187 (*Corresponding authors)
  

Songdi Wu, Ningning Li, Feng Xia, Kastytis Sidlauskas, Xuemei Lin, Yihua Qian, Wei Gao and Qinlu Zhang. Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg Syndrome): case report and literature review.BMC Neurol. 2014, 14(1):231(Page1-4).

 

Weina Yang, Lili Shi, Lianji Chen, Bingyi Zhang, Kaige Ma, Yong Liu, *Yihua Qian. Protective effects of perindopril on D-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampusof mice. Brain Research Bulletin, 2014, 109: 46-53 (*Corresponding authors 

 

Yang WN, Ma KG, Chen XL, Shi LL, Bu G, Hu XD, Han H, Liu Y, *Qian YH. Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells. Neuroscience. 2014, 278: 276-290. (*Corresponding authors)

 

Wei-Na Yang,Xiao-Dan Hu, Hua Han, Li-Li Shi, Gai-Feng Feng,Yong Liu, *Yi-Hua Qian. The effects of valsartan on cognitive deficits induced by aluminium trichloride and D-galactose in mice. Neurological Research, 2014,36(7):651-658(*Corresponding authors)

 

Wei-Na Yang, Hua Han, Xiao-Dan Hu Gai-Feng Feng,*Yi-Hua Qian. The effects of perindopril on cognitive impairment induced by D-galactose and aluminum trichloride via inhibition of acetylcholinesterase activity and oxidative stress. Pharmacology, Biochemistry and Behavior, 2013 , 114-115: 31-36*Corresponding authors

 

Qian YH, Xiao Q, Xu J.The protective effects of tanshinone IIA on β-amyloid protein (1-42)-induced cytotoxicity via activation of the Bcl-xL pathway in neuron.Brain Res Bull. 2012, 88(4): 354-358

 

Shi LL, Yang WN, Chen XL, Zhang JS, Yang PB, Hu XD, Han H, *Qian YH, *Liu Y.The protective effects of tanshinone IIA on neurotoxicity induced by β-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons.Neurochem Int. 201261(2): 227-235 *Corresponding authors

 

He X, Zhang JF, Li ZX, Liu C, Yang LT, Wang N, Han H, *Qian YH, Wen YF, *Xi HJ The traits of five types of tongue movement in Han of Shaanxi, China. Anat Sci Int. 2012,87(4):81-86.*Corresponding authors)

 

Yi-Hua Qian, Qingli Xiao, Hong Chen, Jan Xu. Dexamethasone Inhibits Camptothecin-Induced Apoptosis in C6-Glioma via Activation of Stat5/Bcl-xL Pathway. BBA - Molecular Cell Research, 2009, 1793(5):764-71

 

Qian YH, Han H, Hu XD Shi LL. Protective effect of ginsenoside Rb1 on amyloid protein(1-42)-induced neurotoxicity in cortical neurons. Neurol Res, 2009, 31(7): 663-667.

 

Lu HX, Li MJ, Song TS, Qian YH, Xiao XL, Chen XL, Zhang PB, Feng XS, Terence P, Liu Y. Retrovirus delivered neurotrophin-3 promotes survival, proliferation and neuronal differentiation of human fetal neural stem cells in vitro. BRAIN RESEARCH BULLETIN, 2008,77(4): 158-164

 

Jie-Hua Xu, Hai-Tao Hu, Yong Liu, Yi-Hua Qian, Zhao-Hui Liu,Qing-Rong Tan, Zhang-Jin Zhang.Neuroprotective effects of ebselen are associated with the regulation of Bcl-2 and Bax proteins in cultured mouse cortical neurons. Neuroscience Letters, 2006, 399: 210–214

 

Zhang-Jin Zhang, Yi-Hua Qian, Hai-Tao Hu, Jie Yang, Guang-De Yang.The herbal medicine Dipsacus asper Wall extract reduces the cognitive deficits and overexpression of β-amyloid protein induced by aluminum exposure. Life Sciences ,2003,73(19): 2443-2454

 

Qian YH, Liu Y, Hu HT, Ren HM, Chen XL, Xu JH.The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by b-amyloid protein 25-35.Anatomical Science International,2002,77(3):196-200

 

 
 Wu SD, Xia F, Lin XM, Duan KL, Wang F, Lu QL, Cao H, Qian YH*, Shi M*. Ginsenoside-Rd Promotes Neurite Outgrowth of PC12 Cells through MAPK/ERK- and PI3K/AKT-Dependent Pathways. Int J Mol Sci. 2016 Jan 29;17(2). pii: E177. (*Corresponding authors)