论文著作 - 张涛 - 教师个人主页

课题组致力于：（1）药物过敏反应的分子基础研究；

（2）靶向肥大细胞活性分子筛选分析方法建立；

（3）抗过敏疾病候选化合物药理活性评价。

发表SCI源期刊论文50余篇，近5年主要发表文章列表：

论文标题	作者	发表/完成日期	期刊名称
Alpha-linolenic acid improves nasal mucosa epithelial barrier function in allergic rhinitis by arresting CD4+ T cell differentiation via IL-4Ralpha-JAK2-STAT3 pathway.	Ding Yuanyuan, Wang Yuejin, Zhang Yonghui, Dang Baowen, Hu Shiting, Zhao Chenrui, Huang Yihan, Zheng Guodong, Ma Tianyou, Zhang Tao	2023-07-25	Phytomedicine
Myricetin served as antagonist for negatively regulate MRGPRX2 mediated pseudo-allergic reactions through CD300f/SHP1/SHP2 phosphorylation.	Baowen Dang, Shiting Hu, Yonghui Zhang, Yihan Huang, Tao Zhang, Hongli An	2023-05-01	International Immunopharmacology
A rapid, accurate, and low-cost method for detecting Mycobacterium tuberculosis and its drug-resistant genes in pulmonary tuberculosis: Applications of MassARRAY DNA mass spectrometry.	Yang H, Li A, Dang L, Kang T, Ren F, Ma J, Zhou Y, Yang Y, Lei J, Zhang T.	2023-02-23	Front Microbiol.
Myricetin alleviated immunologic contact urticaria and mast cell degranulation via the PI3K/Akt/NF-κB pathway.	Hu S, Zhang Y, Dang B, Wang Y, Zheng G, Zhang T, An H.	2023-01-17	Phytother Res.
Research on the Adaptive Sensitivity Scanning Method for Ion Conductance Microscopy with High Efficiency and Reliability	Jiao Y, Zhuang J, Zhang T, He L.	2021-09-15	Analytical Chemistry
Paeoniflorin inhibits MRGPRX2-mediated pseudo-allergic reaction via calcium signaling pathway.	Wang J, Zhang Y, Wang J, Liu R, Zhang G, Dong K, Zhang T.	2020-02-14	Phytother Res.
A mast cell specific receptor is critical for granuloma induced by morphine intrathecal infusion	Tao Zhang, Rui Liu, Delu Che,et al.	2019-08-28	Journal of Immunolgoy
Neohesperidin suppresses IgE-mediated anaphylactic reactions and mast cell activation via Lyn-PLC-Ca2+ pathway.	Zhao T, Hu S, Ma P, Che D, Liu R, Zhang Y, Wang J, Li C, Ding Y, Fu J, An H, Gao	2019-08-15	Phytotherapy research
Mast cell-mediated hypersensitivity to fluoroquinolone is MRGPRX2 dependent.	Liu R, Hu S, Zhang Y, Che D, Cao J, Wang J, Zhao T, Jia Q, Wang N, Zhang T*.	2019-05-01	International Immunopharmacology
Dehydroandrographolide inhibits IgE-mediated anaphylactic reactions via calcium signaling pathway.	Che D, Hou Y, Zeng Y, Li C, Zhang Y, Wei D, Hu S, Liu R, An H, Wang Y, Zhang T*.	2019-03-01	Toxicology and Applied Pharmacology.
Quercetin inhibits Mrgprx2-induced pseudo-allergic reaction via PLCγ-IP3R related Ca2+ fluctuations.	Ding Y, Che D, Li C, Cao J, Wang J, Ma P, Zhao T, An H, Zhang T*.	2019-01-01	International Immunopharmacology
RBL-2H3 Cell Model Based on VAMP-8-EGFP Protein for Rapid Detection of Different Allergens.	Cao J, Ma P, Xue W, Ding Y, Zhang Y, Zhang T*	2018-12-01	Acta Biochimica et Biophysica Sinica
Mivacurium induce mast cell activation and pseudo-allergic reactions via MAS-related G protein coupled receptor-X2.	Che D, Wang J, Ding Y, Liu R, Cao J, Zhang Y, Hou Y, An H, Gao Z, Zhang T*.	2018-10-01	Cellular Immunology
The anti-anaphylactoid effects of hydroxysafflor yellow A on the suppression of mast cell Ca2+ influx and degranulation.	Liu R, Zhao T, Che D, Cao J, Wang J, Lv Y, Ma P, Ding Y, Wang N, Wang X, Wang N,	2018-09-14	Phytomedicine
Cisatracurium induces mast cell activation and pseudo-allergic reactions via MRGPRX2.	Delu Che, Liu Rui, Jiao Cao, et al.	2018-09-01	International Immunopharmacology
Typical antimicrobials induce mast cell degranulation and anaphylactoid reactions via MRGPRX2 and its murine homologue MRGPRB2.	Zhang T, Che D, Liu R, et al.	2017-11-01	European Journal of Immunology
Four Main Active Ingredients Derived from a Traditional Chinese Medicine Guanxin Shutong Capsule Cause Cardioprotection during Myocardial Ischemia Injury Calcium Overload Suppression.	Liu F, Huang Z, Sun Y, Li T, Yang D, Xu G, Su Y, Zhang T*.	2017-03-01	Phytotherapy research
Screening anti-tumor compounds from Ligusticum wallichii using cell membrane chromatography combined with high-performance liquid chromatography and mass spectrometry.	Tao Zhang et al.	2015-09-15	J Sep Sci.
Screening antiallergic components from Carthamus tinctorius using rat basophilic leukemia 2H3 cell membrane chromatography combined with high-performance liquid chromatography and tandem mass spectrom	Shengli Han et al.	2015-02-14	J Sep Sci.

论文标题

作者

发表/完成日期

期刊名称

Alpha-linolenic acid improves nasal mucosa epithelial barrier function in allergic rhinitis by arresting CD4+ T cell differentiation via IL-4Ralpha-JAK2-STAT3 pathway.

Ding Yuanyuan, Wang Yuejin, Zhang Yonghui, Dang Baowen, Hu Shiting, Zhao Chenrui, Huang Yihan, Zheng Guodong, Ma Tianyou*, Zhang Tao*

2023-07-25

Phytomedicine

Myricetin served as antagonist for negatively regulate MRGPRX2 mediated pseudo-allergic reactions through CD300f/SHP1/SHP2 phosphorylation.

Baowen Dang, Shiting Hu, Yonghui Zhang, Yihan Huang, Tao Zhang*, Hongli An*

2023-05-01

International Immunopharmacology