Selected Publications

42. Dapeng Li, Zhiwei Cui, Shanshan Xu, Tianqi Xu, Shan Wu, Ayache Bouakaz, Mingxi Wang, Siyuan Zhang. Low-intensity focused ultrasound stimulation treatment decreases blood pressure in spontaneously hypertensive rats. IEEE Transactions on Biomedical Engineering, 2020, Accepted. 

41. Tianqi Xu, Zhiwei Cui, Dapeng Li, Fangyuan Cao, Jichen Xu, Yujin Zong, Supin Wang, Ayache Bouakaz, Mingxi Wan and Siyuan Zhang. Cavitation characteristics of flowing low and high boiling-point perfluorocarbon phase-shift nanodroplets during focused ultrasound exposures. Ultrasonics Sonochemistry, 2020, 65:105060.

40. Zhiwei Cui, Dapeng Li, Shanshan Xu, Tianqi Xu, Shan Wu, Ayache Bouakaz, Mingxi Wan and Siyuan Zhang. Effect of scattered pressures from oscillating microbubbles on neuronal activity in mouse brain under transcranial focused ultrasound stimulation. Ultrasonics Sonochemistry, 2020, 63:104935.

39. Siyuan Zhang, Shan Wu, Shaoqiang Shang, Xuewei Qin, Xin Jia, Dapeng Li, Zhiwei Cui, Tianqi Xu, Gang Niu, Ayache Bouakaz, and Mingxi Wan. Detection and Monitoring of Thermal Lesions Induced by Microwave Ablation Using Ultrasound Imaging and Convolutional Neural Networks. IEEE Journal of Biomedical and Health Informatics, 2020, 24(4):965-973.

38. Zhiwei Cui, Dapeng Li, Yang Feng, Tianqi Xu, Shan Wu, Yibao Li, Ayache Bouakaz, Mingxi Wan and Siyuan Zhang. Enhanced neuronal activity in mouse motor cortex with microbubbles’ oscillations by transcranial focused ultrasound stimulation. Ultrasonics Sonochemistry, 2019, 59:104745.

37. Siyuan Zhang, Tianqi Xu, Zhiwei Cui, Wen Shi, Shan Wu, Yujin Zong, Gang Niu, Xijing He and Mingxi Wan. Time and frequency characteristics of cavitation activity enhanced by flowing phase-shift nanodroplets and lipid-shelled microbubbles during focused ultrasound exposures. Ultrasound in Medicine and Biology, 2019,45(8):2118-2132.

36. Shan Wu, Xuewei Wang, Shaoqiang Shang, Ranxiang Xu, Xuewei Qin, Lei Zhang, Junbo Duan, Supin Wang, Mingxi Wan, and Siyuan Zhang. Effect of logarithmic compression on ultrasonic Nakagami imaging for monitoring of microwave ablation. IEEE International Ultrasonics Symposium, Glasgow, Scotland, UK, October 6-9, 2019.

35. Dapeng Li, Zhiwei Cui, Tianqi Xu, Shan Wu, Yabo Yang, Ayache Bouakaz, Mingxi Wan, and Siyuan Zhang. Focused ultrasound stimulation of the ventrolateral periaqueductal gray decreases blood pressure in spontaneously hypertensive rats.  IEEE International Ultrasonics Symposium, Glasgow, Scotland, UK, October 6-9, 2019.

34. Zhiwei Cui, Fangyuan Cao, Shanshan Xu, Dapeng Li, Tianqi Xu, Shan Wu, Ayache Bouakaz, Mingxi Wan, and Siyuan Zhang. Microbubble-enhanced ultrasonic neuromodulation of motor cortex of mouse. IEEE International Ultrasonics Symposium, Glasgow, Scotland, UK, October 6-9, 2019.

 33. Shan Wu, Shaoqiang Shang, Xuewei Wang, Mingxi Wan, Siyuan Zhang. An in vivo study of ultrasonic monitoring imaging of microwave ablation based on Nakagami statistic parameter. Journal of Biomedical Engineering, 2019, 36(3):371-378.

32. Siyuan Zhang, Shaoqiang Shang, Yuqiang Han, Chunming Gu, Shan Wu, Sihao Liu, Gang Niu, Ayache Bouakaz, and Mingxi Wan. Ex vivo and in vivo monitoring and characterization of thermal lesions by high-intensity focused ultrasound and microwave ablation using ultrasonic Nakagami imaging. IEEE Transactions on Medical Imaging, 2018, 37(7):1701-1710.

31. Siyuan Zhang, Ranxiang Xu, Shaoqiang Shang, Yuqiang Han, Sihao Liu, Tianqi Xu, Chunming Gu, Xingguang Zhu, Gang Niu and Mingxi Wan. In vivo monitoring of microwave ablation in a porcine model using ultrasonic differential attenuation coefficient intercept imaging. International Journal of Hyperthermia, 2018, 34(8):1157-1170.

 30.Dapeng Li, Siyuan Zhang, Zhiwei Cui, Yabo Yang, Bouakaz Ayache and Mingxi Wan. Transcranial focused ultrasound stimulation decrease blood pressure in spontaneously hypertensive rats. IEEE International Ultrasonics Symposium, Kobe, Japan, October 22-25, 2018.

29. Siyuan Zhang, Shaoqiang Shang, Shan Wu, Lei Zhang, Supin Wang and Mingxi Wan. Ultrasound convolutional neural networks imaging for monitoring of microwave ablation. IEEE International Ultrasonics Symposium, Kobe, Japan, October 22-25, 2018.

28. Tianqi Xu, Siyuan Zhang, Zhiwei Cui, Dapeng Li, Fu Mo, Shan Wu and Mingxi Wan. Effects of flowing lipid-shelled microbubbles and phase-shift nanodroplets on the characteristics of cavitation  during focused ultrasound exposure. IEEE International Ultrasonics Symposium, Kobe, Japan, October 22-25, 2018.

27. Siyuan Zhang, Yuqiang Han, Xingguang Zhu, Shaoqiang Shang, Guojing Huang, Lei Zhang, Gang Niu, Supin Wang, and Mingxi Wan. Feasibility of using ultrasonic Nakagami imaging for monitoring microwave-induced thermal lesion in ex vivo porcine liver. Ultrasound in Medicine and Biology, 2017,43(2):482-493.

26. Siyuan Zhang, Zhiwei Cui, Tianqi Xu, Pan Liu, Dapeng Li, Shaoqiang Shang, Ranxiang Xu, Yujin Zong, Gang Niu, Supin Wang, Xijing He and Mingxi Wan. Inverse effects of flowing phase-shift nanodroplets and lipid-shelled microbubbles on subsequent cavitation during focused ultrasound exposures. Ultrasonics Sonochemistry, 2017, 34(1):400-409.

25. Siyuan Zhang, Chong Li, Fanyu Zhou, Supin Wang and Mingxi Wan. Evaluate thermal lesion using Nakagami imaging for monitoring of high-intensity focused ultrasound. AIP Conference Proceedings, 2017, 1816: 050002,1-5.

24. Siyuan Zhang, Zhiwei Cui, Chong Li, Fanyu Zhou, Yujin Zong, Supin Wang and Mingxi Wan. Enhanced cavitation and heating of flowing polymer- and lipid-shelled microbubbles and phase-shift nanodroplets during focused ultrasound exposures. AIP Conference Proceedings, 2017, 1816: 070001,1-5.

23. Siyuan Zhang, Shaoqiang Shang , Yuqiang Han , Ranxiang Xu, Sihao Liu , Lei Zhang, Shan Wu , Gang Niu, Sanhong Wang, Mingxi Wan. Monitoring of microwave ablation in porcine liver using ultrasonic Nakagami imaging. IEEE International Ultrasonics Symposium,1-4, Washington, D.C., USA, September 6-9, 2017.

22. Ting Ding, Zhiguo Gui, Siyuan Zhang, Luyang Ma and Mingxi Wan. Ultrasound imaging with enhanced lesion-to-bubble ratio based on wavelet transform for monitoring of high-intensity focused ultrasound. IEEE International Ultrasonics Symposium, Washington, D.C., USA, September 6-9, 2017.

21. Siyuan Zhang, Tianqi Xu, Ziwei Cui, Sihao Liu, Dapeng Li, Rui Guo, Junjie Wang, Yujin Zong, Gang Niu, and Mingxi Wan. Compare ultrasound-mediated cavitation between flowing phase-shift nanodroplets and lipid-shelled microbubbles during focused ultrasound exposures.The 17th International Symposium on Therapeutic Ultrasound, China, Nanjing, May 31-june 2,2017.   

20. Siyuan Zhang, Shaoqiang Shang, Yuqiang Han, Ranxiang Xu, Chunming Gu,  Lei Zhang, Shan Wu, Gang Niu, and Mingxi Wan. In vivo and ex vivo monitoring of thermal ablation in a porcine model using ultrasonic nakagami imaging.The 17th International Symposium on Therapeutic Ultrasound, China, Nanjing, May 31-june 2,2017. 

19. Mingxi Wan, Siyuan Zhang, Mingzhu Lu, Hong Hu, Bowen Jing, Runna Liu and Hui Zhong. Strategy of High Efficiency and Refined High-intensity Focused Ultrasound and Ultrasound Monitoring Imaging of Thermal Lesion and Cavitation.  AIP Conference Proceedings, 2017, 1821: 060002.

18. Hong Hu, Shanshan Xu, Diya Wang, Runna Liu, Yuan Yuan, Siyuan Zhang, Supin Wang and Mingxi Wan. Ultrasonic concentration imaging of cavitation bubbles using Nakagami statistical model. IEEE International Ultrasonics Symposium,1-4, Tours, France, September 18-21, 2016.

17. Junbo Duan, Hui Zhong, Bowen Jing, Siyuan Zhang and Mingxi Wan. Increasing Axial Resolution of Ultrasonic Imaging With a Joint Sparse Representation Model. IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control. 2016;63(12):2045-56.

16. Siyuan Zhang, Zhiwei Cui, Lei Zhang, Xingguang Zhu, Tianqi Xu, Supin Wang, XijingHe, and Mingxi Wan. Feasibility of acoustic evaluation of thermal lesions at bone-soft tissue interface of an ex vivo bovine bone exposed to high-intensity focused ultrasound. IEEE International Ultrasonics Symposium, 1-4, Taipei, China, October 21-24, 2015.

15. Weidong Song, Siyuan Zhang, Jinjin Wan and Mingxi Wan. Monitoring imaging of lesions induced by high intensity focused ultrasound based on a matching pursuit method. IEEE International Ultrasonics Symposium, 1-4, Taipei, China, October 21-24, 2015.

14.Junbo Duan, Hui Zhong, Bowen Jing, Siyuan Zhang, and Mingxi Wan. Discover layered structure in ultrasound images with a joint sparse representation model. IEEE International Ultrasonics Symposium, 1-4, Taipei, China, October 21-24, 2015.

13. Siyuan Zhang,Zhiwei Cui, Supin Wang, and Mingxi Wan. Nearby thermal ablation and acoustic evaluation of surface thermal injury of an ex vivo bovine bone exposed to high-intensity focused ultrasound. The 15th International Symposium on Therapeutic Ultrasound, Utrecht, Netherlands, April 15-18, 2015.

12. Siyuan Zhang, Chong Li, Fanyu Zhou, Mingxi Wan and Supin Wang. Enhanced Lesion-to-Bubble Ratio on Ultrasonic Nakagami Imaging for Monitoring of High-Intensity Focused Ultrasound. Journal of Ultrasound in Medicine. 2014;33(6):959-970.

11. Ting Ding, Siyuan Zhang (Co-first author), Quanyou Fu, Zhian Xu and Mingxi Wan. Ultrasound line-by-line scanning method of spatial-temporal active cavitation mapping for high-intensity focused ultrasound. Ultrasonics, 2014, 54(1):147-155.

10. Shanshan Xu, Yujin Zong, Wusong Li, Siyuan Zhang, and Mingxi Wan. Bubble size distribution in acoustic droplet vaporization via dissolution using an ultrasound wide-beam method. Ultrasonics Sonochemistry, 2014, 21(3):975-983. 

9. Siyuan Zhang, Chong Li, Hui Yin, Supin Wang, and Mingxi Wan. Surface vibration and nearby cavitation of an ex vivo bovine femur exposed to high intensity focused ultrasound. Journal of the Acoustical Society of America, 2013, 134(2): 1656-1662.

8. Siyuan Zhang, Yujin Zong, Mingxi Wan, Xiaojun Yu, Quanyou Fu, Ting Ding, Fanyu Zhou, and Supin Wang. Compare ultrasound-mediated heating and cavitation between flowing polymer- and lipid-shelled microbubbles during focused ultrasound exposures. Journal of the Acoustical Society of America, 2012, 131 (6): 4845-4855.

7. Siyuan Zhang, Fanyu Zhou, Mingxi Wan, Min Wei, Quanyou Fu, Xing Wang, and Supin Wang. Feasibility of using Nakagami distribution in evaluating the formation of ultrasound-induced thermal lesions. Journal of the Acoustical Society of America, 2012, 131 (6): 4836-4844.

6. Siyuan Zhang, Yangzi Qiao, and Mingxi Wan. Acoustic, thermal and sonoluminescence investigation of enhanced cavitation of flowing polymer- and lipid-shelled microbubbles during focused ultrasound exposures. Journal of the Acoustical Society of America, 2012, 131(4): 3228-3228.

5. Yiyang Wan, Siyuan Zhang, Yujin Zong, and Mingxi Wan. Formation of two-way Lamb waves and force potential wells using single conventional ultrasonic transducer and sheep horn shaped metal piece. Journal of the Acoustical Society of America, 2012, 131(4): 3339-3339.

4. Siyuan Zhang, Ting Ding, Mingxi Wan, Hujie Jiang, Xu Yang, Hui Zhong, and Supin Wang. Minimizing the thermal losses from perfusion during focused ultrasound exposures with flowing microbubbles. Journal of the Acoustical Society of America, 2011, 129(4): 2336-2344. 

3. Dachun Zhang, Siyuan Zhang, Mingxi Wan, and Supin Wang. A fast tissue stiffness-dependent elastography for HIFU-induced lesions inspection. Ultrasonics, 2011, 51(8):857-869. 

2. Hui Zhong, Mingxi Wan, and Siyuan Zhang. Monitoring dynamic characteristics of treated region during high intensity focused ultrasound (HIFU) treatment. 2011 Proceedings of International Symposium on Bioelectronics and Bioinformatics, Suzhou, China,November, 88-91,2011.

1. Siyuan Zhang, Mingxi Wan, Hui Zhong, Cheng Xu, Zhenzhong Liao, Huanqing Liu, and Supin Wang.  Dynamic changes of integrated backscatter, attenuation coefficient and bubble activities during high-intensity focused ultrasound (HIFU) treatment. Ultrasound in Medicine and Biology, 2009, 35(11): 1828-1844.

Monographs

1.  Siyuan Zhang, Mingxi Wan, and ter Haar G,“Chapter 4 Cavitation enhanced thermal effects and their applications,” in Book: Cavitation in biomedicine: principles and techniques, Editor: Wan MX, Feng Y, and ter Haar G, Springer, 2015. ISBN: 978-94-017-7254-9.

2.  张思远,徐田奇万明习等2 治疗超声中生物组织温度场。万明习,冯怡,路舒宽,计算生物医学超声学,北京:科学出版社,2019 (ISBN: 978-7-03-059103-6, 获国家科学技术学术著作出版基金资助)。

Patents

12. Siyuan Zhang, Zhiwei Cui, Dapeng Li, Tianqi Xu, Shan Wu, Mingxi Wan.High-spatial-resolution ultrasonic neuromodulation method and system, USA, Publication No. US2020/0078606A1, Publication Date: 2020.03.12.

11. Siyuan Zhang, Shan Wu, Shaoqiang Shang, Zhiwei Cui, Tianqi Xu, Mingxi Wan. Recognition, monitoring, and imaging method and system for thermal ablation region based on ultrasonic deep learning. USA, Publication No. US2020/0121376A1, Publication Date: 2020.04.23.

10.张思远,徐冉翔,崔智炜,李大鹏,徐田奇,尚少强,万明习。一种无线控制的可穿戴式超声神经刺激装置,中国,授权专利号:ZL201610327257.7 

9.张思远,崔智炜,徐冉翔,尚少强,李大鹏,徐田奇,李延海,万明习。可穿戴经颅超声神经刺激与电生理记录联合系统与方法,中国,授权专利号:ZL201610326489.0

8.张思远,王华,崔智炜,李大鹏,徐田奇,吴珊,万明习。一种高空间分辨率超声神经调控方法及系统,中国,授权专利号:ZL201811036875.1 

7.张思远,吴珊,尚少强,崔智炜,徐田奇,万明习。基于超声深度学习的热消融区域识别监测成像方法与系统,中国,授权专利号:ZL201811226651.7 

6.张思远,李大鹏,崔智炜,徐田奇,吴珊,杨雅博,万明习。一种基于超声神经刺激的无创血压调控系统,中国,授权专利号:ZL201811081537.X

5.张思远,崔智炜,徐冉翔,李大鹏,尚少强,徐田奇,李延海,郑良,万明习。用于经颅超声神经刺激的脑部电生理信号记录装置及方法,中国,专利申请号:201610326628.X

4.张思远,朱兴广,韩玉强, 黄国静,尚少强, 徐田奇,万明习,段君博,钟徽。一种用于热凝固监测的超声回波统计参量成像系统与方法,中国,专利申请号:201610326626.0

3.张思远,尚少强,徐冉祥,吴珊,崔智炜,徐田奇,李大鹏,万明习。基于深度学习的生物组织热消融超声监控成像软件V1.0。中国,软件著作权,2018SR243321

2.万明习, 张思远,蒋胡杰,钟徽,丁婷,廖振中,王素品。一种瞬态物理过程中多模式和多参量同步检测成像监控系统及监控方法: 中国, 授权专利号: ZL200910023529.4

1.万明习,丁婷,柳杨, 张思远。聚焦超声空化及其微汽泡实时提取装置与检测方法: 中国, 授权专利号:ZL200910021773.7

 

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