基本信息

 徐姗姗,女,1983年生,博士,西安交通大学,生命科学与技术学院生物医学工程系。

 

教育经历:

2007/03-2014/06,西安交通大学,生物医学工程系,博士,导师:万明习

2005/09-2007/02, 西安交通大学,生物医学工程系,硕士阶段(硕博连读),导师:万明习

2001/09-2005/07, 西安交通大学,生物医学工程系,学士

科研与学术工作经历:

2018/11-至今,西安交通大学,生物医学工程系,副教授

2016/12-2017/12, 美国华盛顿大学圣路易斯分校,生物医学工程系,访问学者

2014/07-2018/11,西安交通大学,生物医学工程系,讲师

2014/07-2018/12,西安交通大学,生物系,博士后,合作导师:王素品

联系方式

 手机18629530636          Emailxushanshan@xjtu.edu.cn  西安交通大学生命学院教二北105

站点计数器
研究领域

 主持或参加科研项目(课题):

8. 国家自然科学基金面上项目,31771075,超声/磁场对双峰分布双模相变纳米液滴的协同操控及其在肿瘤诊疗中的应用,2018/01-

2021/1258万元,在研,参加。

7. 国家自然科学基金青年项目,11504289,双频控制组织中纳米液滴相变微泡、成核阈值与区域及高效精细治疗,2016/01-2018/1224

万元,在研,主持。

6.国家重点研发计划数字诊疗装备研发重点专项,2016YFC0100700,经颅三维动态超声微泡与空化成像技术及诊疗应用,2016/07-

2018/12,340万元,在研,参加。

5. 国家重点研发计划数字诊疗装备研发重点专项,2016YFC0104704,动态实时三维高端超声造影成像技, 2016/07-2020/12,35万元,在研,参加。

4. 国家自然科学基金面上项目,31470909,基于可控空化内皮损伤的动脉粥样硬化斑块动物模型及其活体评价,2015/01-2018/12, 85万元,在研,参加。

3. 中央高校基本科研业务费专项资金资助——国际前沿与自主创新类项目,xjj2015053,基于双频共焦超声激励的微纳相变材料空化增效

和调控技术,2015/01-2017/12, 8万元,结题,主持。

2.西安交通大学“新教师科研支持计划”,双频共焦超声联合纳米相变材料高效精准超声溶栓治疗,2015/01-2017/1210万元,结题,主

持。

1. 国家自然科学基金青年项目,81201105,低强度聚焦超声协同靶向微泡抗肿瘤血管生成方法及瞬态空化力生物学效应机制,2013/01-

2015/1223万元,结题,参加。

代表性研究成果和学术奖励情况

 一、 期刊论文

15. Shanshan Xu, Yujin Zong, Yi Feng, Runna Liu, Xiaodong Liu, Yaxin Hu, Shimin Han, Mingxi Wan*, Dependence of pulsed focused ultrasound induced thrombolysis on duty cycle and bubble size distribution, Ultrasonics Sonochemistry, 2015, 22: 160-166 

14. Shanshan Xu, Hong Hu, Hujie Jiang, Zhi’an Xu, Mingxi Wan*, Ultrafast 2-D imaging monitoring and array-based PCD for UCAs destruction in a variable-sized region, Journal of Ultrasound in Medicine, 2014, 33(11): 1957-1970 

13. Shanshan Xu, Yujin Zong, Wusong Li, Siyuan Zhang, Mingxi Wan*, Bubble size distribution in acoustic droplet vaporization via dissolution using an ultrasound wide-beam method, Ultrasonics Sonochemistry, 2014, 21(3):957-983

12. Shanshan Xu, Nan Chang, Rui Wang, Xiaodong Liu, Shifang Guo, Supin Wang, Yujin Zong*, Mingxi Wan*, Acoustic droplet vaporization and inertial cavitation thresholds and efficiencies of nanodroplets emulsions inside the focused region using a dual-frequency ring focused ultrasound, Ultrasonics Sonochemistry, 2018, 48: 532-537 

11. Diya Wang, Shanshan Xu, Kejia Zhang, Xinyu Zhang, Xuan Yang, Mengnan Xiao, Qiang Su*, Mingxi Wan*. A Fast Scheme for Renal Microvascular Perfusion Functional Imaging on Low-cost Ultrasound Platform: Evaluated by a Multi-parametric Model. Medical Physics, 201946738-745

10. Nanchang, Dui Qin, Pengying Wu, Shanshan Xu, Supin Wang, Mingxi Wan. IR780 loaded perfluorohexane nanodroplets for efficient sonodynamic therapy induced by short-pulsed focused ultrasound. Ultrasonics Sonochemistry (Accepted)

9.  Shifang Guo, Aiwei Shi, Shanshan Xu, Xuan Du, Xin Wang, Yujin Zong, Ayache Bouakaz, Mingxi Wan*, Lowering of acoustic droplet vaporization threshold via aggregation, Applied Physics Letters, 2017, 111 (25) :254102 

8.  Diya Wang, Mengnan Xiao, Yu Zhang, Hong Hu, Shanshan Xu, Yujing Zong, Mingxi Wan*, DCEUS-based Focal Perfusion Imaging of Intratumoral Microvessel with Single-pixel Resolution and High Signal to Clutter Ratio, Ultrasonics, 2018, 84: 392-403.

7.  Shifang Guo, Xuan Du, Xin Wang, Shukuan Lu, Aiwei Shi, Shanshan Xu, Ayache Bouakaz, Mingxi Wan*, Reduced clot debris size using standing waves formed via high intensity focused ultrasound, Applied Physics Letters, 2017,111(12): 123701 

6.   Chen Bai, Shanshan Xu, Junbo Duan, Bowen Jing, Miao Yang, Mingxi Wan*, Pulse-inversion Subharmonic Ultrafast Active Cavitation Imaging in Tissue Using Fast Eigenspace-Based Adaptive Beamforming and Cavitation Deconvolution, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2017, 64(8): 1175-1193

5 Shukuan Lu, Shanshan Xu, Runna Liu, Hong Hu, Mingxi Wan*, High-contrast active cavitation imaging technique based on multiple bubble wavelet transform, The Journal of the Acoustic Society of America, 2016, 140(2):1000-1011

4.  Runna Liu, Shanshan Xu, Hong Hu, Rui Huo,Supin Wang, Mingxi Wan*, Wavelet-transform-based active imaging of cavitation bubbles in tissues induced by high intensity focused ultrasound. The Journal of the Acoustic Society of America, 2016, 140(2):798-805 

3.   Hui Yin, Nan Chang, Shanshan Xu, Mingxi Wan*, Sonoluminescence characterization of inertial cavitation inside a BSA phantom treated by pulsed HIFU, Ultrasonics Sonochemistry, 2016, 32: 158-164 

2.   Runna Liu, Hong Hu, Shanshan Xu, Rui Huo, Supin Wang, Mingxi Wan*, Ultrafast active cavitation imaging with enhanced cavitation to tissue ratio based on wavelet transform and pulse inversion, The Journal of the Acoustical Society of America, 2015, 137(6), 3099-3106

1.   Hong Hu, Shanshan Xu, Yuan Yuan, Runna Liu, Supin Wang, Mingxi Wan*, Spatial-temporal ultrasound imaging of residual cavitation bubbles around a fluid-tissue interface in histotripsy, The Journal of the Acoustical Society of America, 2015, 137(5), 2563-2572 

二、 专著

6.     徐姗姗,郭世放,刘晓东等. 11 超声空化与声致液滴相变, 万明习,冯怡,路舒宽,计算生物医学超声学,北京:科学出版社,2019.01. (ISBN: 978-7-03-059103-6)

5.   Shanshan Xu, Yangzi Qiao, Xiaodong Liu, Charles C Church, Mingxi Wan., “Chapter 1: Fundamentals of Cavitation,” in Book: Cavitation in Biomedicine-Principles and Techniques. Editor: Mingxi Wan, Yi Feng, Gail ter Harr, Springer, 2015

4.     Shanshan Xu, Xiaodong Liu, Mingxi Wan, “Chapter 3: Size Distribution of Cavitation Bubbles,” in Book: Cavitation in Biomedicine-Principles and Techniques, Editor: Mingxi Wan, Y Feng, Gail ter Haar, Springer, 2015.

3.    Yujin Zong, Shanshan Xu, Tom Matula, Mingxi Wan, “Chapter 5: Cavitation Enhanced Mechanical Effects and Applications” in Book: Cavitation in Biomedicine-Principles and Techniques, Editor: Mingxi Wan, Y Feng, Gail ter Haar, Springer, 2015.

2.    Yangzi Qiao, Shanshan Xu, Nan Chang, Hui Yin, Mingxi Wan, “Chapter 6: Cavitation Control and Applications” in Book: Cavitation in Biomedicine-Principles and Techniques, Editor: Mingxi Wan, Y Feng, Gail ter Haar, Springer, 2015.

1.      蒋胡杰,徐姗姗,第6 超声阵列波束合成及其声场测试,见“万明习,宗瑜瑾,王素品,陆明珠,生物医学超声实验,西安交通大学出版社,2010

三、授权发明专利

4.      万明习,徐姗姗,一种在溶液中消散过程对微泡群尺寸分布进行估计的方法,2015.10.28,中国,ZL201310079838.X

3.     万明习,胡亚欣,徐姗姗,蒋胡杰,基于阵列换能器的低强度聚焦超声药物控释与监控装置,2009.9.1,中国,ZL200910023755.2

2.      万明习,柏晨,徐姗姗,敬博文,压缩自适应波束合成的平面波超声成像和微泡成像的方法与系统,2016.4.27,中国,ZL201510079932.4

1. 万明习,徐姗姗,刘晓东,宗瑜瑾,陆明珠, 基于双频共焦超声分时激励的超声力学毁损和热凝固装置及方法,2017. 12. 15,中国, ZL201410456237.0

四、 学术任职

陕西省超声医学工程学会青年委员会副主任委员

中国医学装备协会超声装备技术分会超声换能器及材料专委会委员

中国超声医学工程学会分子影像专委会青年委员