基本信息

  

               

    杨骁,理学博士,助理研究员,现就职于西安交通大学第二附属医院。2017年毕业于中国医学科学院&北京协和医学院,血液学研究所。

   主要从事肿瘤免疫等方向的研究,作为课题负责人申请获得国家自然科学基金青年基金、陕西省自然科学基金。

  以第一/共同第一作者在SCI杂志如Haematologica、OncoImmunology、Immunobiology发表论文3篇,以参与作者在SCI杂志Cancer letter、Cell Death & Disease、The Journal of Immunology、Immunology and Cell Biology、Molecular Immunology、Stem Cell Reviews and Reports等发表论文9篇。相关研究内容请点击Researchgate个人主页。

      

 

联系方式

 yang_x@xjtu.edu.cn;

 yangxiao1989@live.com

站点计数器
研究领域

Reasarch interest:

  1. Tumor Immunology;

  2. Leukemia Immuno-microenvironment;

Publication:

 [1] Feng W, Yang X, Wang L, Wang R, Yang F, Wang H, Liu X, Ren Q, Zhang Y, Zhu X, Zheng G. P2X7 promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of Pbx3[J]. Haematologica. 2020. Co-first author

 [2]  Wang R, Feng W, Wang H, Wang L, Yang X, Yang F, Zhang Y, Liu X, Zhang D, Ren Q, Feng X, Zheng G. Blocking migration of regulatory T cells to leukemic hematopoietic microenvironment delays disease progression in mouse leukemia model[J]. Cancer Lett. 2020.

 [3] Yang X, Feng W, Wang R, Yang F, Wang L, Chen S, Ru Y, Cheng T, Zheng G. Repolarizing heterogeneous leukemia-associated macrophages with more M1 characteristics eliminates their pro-leukemic effects[J]. Oncoimmunology. 2018, 7(4): e1412910. [4] Yang X, Feng W, Wang R, Yang F, Wang L, Chen S, Chen C, Ren Q, Zheng G. Hepatic leukemia-associated macrophages exhibit a pro-inflammatory phenotype in Notch1-induced acute T cell leukemia[J]. Immunobiology. 2018, 223(1): 73-80.

  [4] Yang X, Feng W, Wang R, Yang F, Wang L, Chen S, Chen C, Ren Q, Zheng G. Hepatic leukemia-associated macrophages exhibit a pro-inflammatory phenotype in Notch1-induced acute T cell leukemia[J]. Immunobiology. 2018, 223(1): 73-80.

 [5] Wang L, Feng W, Yang X, Yang F, Wang R, Ren Q, Zhu X, Zheng G. Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-kappaB and beta-catenin/TCF signaling pathways[J]. Cell Death Dis. 2018, 9(4): 427.

 [6] Wang R, Feng W, Yang F, Yang X, Wang L, Chen C, Hu Y, Ren Q, Zheng G. Heterogeneous effects of M-CSF isoforms on the progression of MLL-AF9 leukemia[J]. Immunol Cell Biol. 2018, 96(2): 190-203. 

 [7] Yang F, Wang R, Feng W, Chen C, Yang X, Wang L, Hu Y, Ren Q, Zheng G. Characteristics of NK cells from leukemic microenvironment in MLL-AF9 induced acute myeloid leukemia[J]. Molecular Immunology. 2018, 93: 68-78.

 [8] Chen S, Yang X, Feng W, Yang F, Wang R, Chen C, Wang L, Lin Y, Ren Q, Zheng G. Characterization of peritoneal leukemia-associated macrophages in Notch1-induced mouse T cell acute lymphoblastic leukemia[J]. Molecular Immunology. 2017, 81: 35-41. 

 [9] Liao J, Feng W, Wang R, Ma S, Wang L, Yang X, Yang F, Lin Y, Ren Q, Zheng G. Diverse in vivo effects of soluble and membrane-bound M-CSF on tumor-associated macrophages in lymphoma xenograft model[J]. Oncotarget. 2016, 7(2): 1354-1366.

[10]Feng W, Yang F, Wang R, Yang X, Wang L, Chen C, Liao J, Lin Y, Ren Q, Zheng G. High Level P2X7-Mediated Signaling Impairs Function of Hematopoietic Stem/Progenitor Cells[J]. Stem Cell Rev. 2016, 12(3): 305-314.

[11] Chen S Y, Yang X, Feng W L, Liao J F, Wang L N, Feng L, Lin Y M, Ren Q, Zheng G G. Organ-specific microenvironment modifies diverse functional and phenotypic characteristics of leukemia-associated macrophages in mouse T cell acute lymphoblastic leukemia[J]. J Immunol. 2015, 194(6): 2919-2929.

[12] Chen S, Feng W, Yang X, Yang W, Ru Y, Liao J, Wang L, Lin Y, Ren Q, Zheng G. Functional expression of P2X family receptors in macrophages is affected by microenvironment in mouse T cell acute lymphoblastic leukemia[J]. Biochemical and Biophysical Research

[13] 陈莎燕,冯文利,杨骁,等. P2X家族受体在急性T淋巴细胞白血病小鼠腹腔巨噬细胞中的表达[J]. 中国实验血液学杂志. 2014(03): 623-628.

[14] 冯丽,杨骁,廖金凤,等. 白血病细胞中共表达P2X7受体和Notch1胞内区[J]. 中国实验血液学杂志. 2013, 21(3): 544-549.