Scientific Research


     We aim to achieve biochemical assay, such as biological sample purification and polymerase chain reaction (PCR), into integrated microfluidic chips or micro total analysis systems (μ-TAS). The femtosecond laser irradiation followed by chemical etching (FLICE) technology was used to fabricate microfluidic microstructures embedded in fused silica. By combining the FLICE technology with photolithographic processing techniques, components for the microfluidic system were achieved, including 3D helical micromixers and helical microinductors. Functions of DNA purification using super-paramagnetic beads, fluorescence genetic dectection and real-time PCR assay could be achieved in the microfluidic system.
 

 

 

Recent Publications 

   J. Yong,  Q. Yang,  F. Chen,  D. Zhang,  U. Farooq,  G. Du and X. Hou,  A simple way to achieve superhydrophobicity, controllable water adhesion, anisotropic sliding, and anisotropic wetting based on femtosecond-laser-induced line-patterned surfaces, J. Mater. Chem. A 2, 5499 (2014)

   Jiale Yong,   Qing Yang,   Feng Chen,   Dongshi Zhang,  Guangqing Du,   Hao Bian,   Jinhai Si and   Xun Hou ,  Bioinspired Superhydrophobic Surfaces with Directional Adhesion , RSC Adv.,  4, 8138 (2014)

   Qing Yang, Guangqing Du, Feng Chen, Investigation on the electron dynamics of periodic nanoripple formation on fused silica induced by temporally shaped femtosecond laser, Acta Phys Sin. 63 4 (2014)

   Feng Chen, Zefang Deng, Qing Yang, Hao Bian, Guangqing Du, Jinhai Si, and Xun Hou, Rapid fabrication of a large-area close-packed quasi-periodic microlens array on BK7 glass, Opt. Lett. 39, 606 (2014)

   G.Q. Du, Q. Yang, F. Chen, Y. Ou, Y.M. Wu,Y. Lu, H. Bian and X. Hou, Ultrafast dynamics of high-contrast nano-grating formation on gold film induced by temporally shaped femtosecond laser. Chem. Phys. Lett. 597, 153 (2014)

   J. Yong, Q. Yang, F. Chen, D. Zhang, G. Du, J.Si, F. Yun and X. HouA bioinspired planar superhydrophobic microboat, J. Micromech. Microeng. 24, 035006 (2014)

   Jiale Yong, Qing Yang, Feng Chen, Dongshi Zhang, Guangqing Du, Hao Bian,Jinhai Si, Feng Yun, Xun Hou, Superhydrophobic PDMS surfaces with three-dimensional (3D) pattern-dependent controllable adhesion. Appl. Surf. Sci. 288, 579 (2014)

   Yang Hu, Qing Yang, Feng Chen,Hao Bian, Zefang Deng, Guangqing Du, Jinhai Si, Feng Yun, Xun Hou, Cost-efficient and flexible fabrication of rectangular-shaped microlens arrays with controllable aspect ratio and spherical morphology, Appl. Surf. Sci. 292,285 (2014)

   Keyin Liu, Qing Yang,Yulong Zhao, Feng Chen, Chao Shan, Shengguan He, Xiaole Fan, Lei li, Xiangwei Meng, Guangqing Du, Hao Bian, Three-dimensional Metallic Microcomponents Achieved in Fused Silica by A Femtosecond-laser-based Microsolidifying Process, Microelectronic Engineering 113,932014

   Feng Chen,  Dongshi Zhang , Qing Yang , Jiale Yong , Guangqing Du , Jinhai Si , Feng Yun , and Xun Hou, Bioinspired Wetting Surface via Laser Microfabrication, ACS Appl. Mater. Interfaces 5(15), 6777(2013)

   Feng Chen, Chao Shan, Keyin Liu, Qing Yang, Xiangwei Meng, Shengguan He, Jinhai Si , Xun Hou, Process for the fabrication of complex three-dimensional microcoils in fused silica, Opt. Lett. 38(15),2911(2013)

   Yong J, Chen F, Yang Q, Du G, Bian H, Zhang D, Si J, Yun F, Hou XRapid Fabrication of Large-Area Concave Microlens Arrays on PDMS by a Femtosecond Laser. ACS Appl Mater Interfaces 5,9382 2013

   GQ Du, Q. Yang, F. Chen,  JH Si, F. Yun and X. Hou, Ultrafast electron dynamics manipulation of laser induced periodic ripples via a train of shaped pulses, Laser Phys. Lett. 10, 026003 (2013).      

   Jiale Yong , Feng Chen, Qing Yang , Dongshi Zhang , Guangqing Du , Jinhai Si , Feng Yun and Xun HouFemtosecond Laser Weaving Superhydrophobic Patterned PDMS Surfaces with Tunable Adhesion J. Phys. Chem. C. 117 , 24907 (2013) 

   Jiale Yong, Feng Chen, Qing Yang, Dongshi Zhang, Hao Bian, Guangqing Du, Jinhai Si, Xiangwei Meng, Xun Hou, Controllable Adhesive Superhydrophobic Surfaces Based on PDMS Microwell Arrays, Langmuir 29,3274 (2013)

   Xiangwei Meng, Feng Chen, Qing Yang, Hao Bian, Hewei Liu, Pubo Qu, Yang Hu, Jinhai Si, Xun Hou, A  Simple Way to Fabricate Close-Packed High Numerical Aperture Microlens Arrays, IEEE Photonics Technology Letters 25(14)1336 (2013)

   Hao Bian, Qing Yang, Feng Chen, Hewei Liu, Guangqing Du, Zefang Deng, Jinhai Si, Feng Yun, Xun Hou, Scalable shape-controlled fabrication of curved microstructures using a femtosecond laser wet-etching process, Materials Science and Engineering: C 33, 2795 (2013)

   Hao Bian, Qing Yang, Hewei Liu, Feng Chen, Guangqing Du, Jinhai Si, and Xun Hou, A facile preparation route for netlike microstructures on a stainless steel using an ethanol-mediated femtosecond laser irradiation, Materials Science & Engineering C 33, 663 (2013)

   Jiale Yong, Qing Yang, Feng Chen, Dongshi Zhang, Hao Bian, Yan Ou, Jinhai Si, Guangqing Du, Xun Hou, Stable superhydrophobic surface with hierarchical mesh-porous structure fabricated by a femtosecond laser, Applied Physics A 111,1  (2013)

  Guangqing Du, Qing Yang, Feng Chen, Xiangwei Meng, Hao Bian, Jinhai Si, Xun Hou, Ultrafast dynamics of thermionic emission on Au film under femtosecond laser excitation, Applied Physics A 112, 22013

   Keyin Liu, Qing Yang, Shengguan He, Feng Chen, Yulong Zhao, Xiaole Fan, Lei Li, Chao Shan and Hao Bian, A high-efficiency three-dimensional helical micromixer in fused silica, Microsystem Technologies 1910332013

  Keyin Liu, Qing Yang, Yulong Zhao, Feng Chen, Chao Shan, Fabrication and analytical evaluation of three-dimensional microsolenoids achieved in fused silica by femtosecond-laser-based microsolidifying process, Micro & Nano Letters 8, 623 (2013)

 Hewei Liu, Feng Chen, Qing Yang, Pubo Qu, Jinhai Si and Xun Hou, Fabrication of bioinspired omnidirectional and gapless microlens array for wide field-of-view detections, Appl. Phys. Lett., 100, 133701, 2012 ( cover paper).


 Bian Hao, Hewei Liu, Feng Chen, Qing Yang, Pubo Qu, Guangqing Du, Jinhai Si, Xianhua Wang, and Xun Hou, Versatile route to gapless microlens arrays using laser-tunablewet-etched curved surfaces, Opt. Express, 20, 12939 (2012).


 Pubo Qu, Feng Chen, Hewei Liu, Qing Yang, Jing Lu, Jinhai Si, Yiqing Wang and Xun Hou, A simple route to fabricate artificial compound eye structures, Opt. Express, 20, 5775 (2012).


 Xianhua Wang; Feng Chen; Hewei Liu, Fabrication qualities of micro-gratings encoding dependence on laser parameters by two-beam femtosecond lasers interference, Micromachining and Microfabrication Process Technology XVII, Proceedings of the SPIE, V8248, San Francisco, USA ( 2012)


 Hewei Liu; Feng Chen; Qing Yang;Facile and flexible fabrication of gapless microlens arrays using a femtosecond laser microfabrication and replication process, Laser Applications in Microelectronic and Optoelectronic Manufacturing (LAMOM) XVII, Proceedings of the SPIE, V8243, San Francisco, USA (2012)


 Dongshi Zhang, Feng Chen, Qing Yang, Jinhai Si and Xun Hou, Mutual wetting transition between isotropic and anisotropic on directional structures fabricated by femotosecond laser, Soft Matter (SCI-1区, IF: 4.5), 7, 8337 (2011).


 Feng Chen, Dongshi Zhang, Qing Yang, Xianhua Wang, Baojiang Dai, Xiangming Li, Xiuqing Hao, Yucheng Ding, Jinhai Si and Xun Hou, Anisotropic wetting on microstrips surface fabricated by femtosecond laser, Langmuir (IF: 4.3), 27, 359 (2011).


 Feng Chen, Guangqing Du, Qing Yang, Jinhai Si and Xun Hou, Ultrafast heating characteristics in multi-layer metal film assembly under femtosecond laser pulses irradiation,  Two Phase Flow, Phase Change and Numerical Modeling (Book), ISBN 978-953-307-584-6, Chapter 11, 239-254, Published by Intech, Aug 2011.


 Feng Chen, Hewei Liu, Qing Yang, Xianhua Wang, Cong Hou, Hao Bian, Weiwei Lang, Jinhai Si and Xun Hou, Maskless fabrication of concave microlens arrays on silica glasses by a femtosecond-laser-enhanced local wet etching method, Opt. Express, 18, 20334 (2010).


 Dongshi Zhang, Feng Chen, Guoping Fang, Qing Yang, Degang Xie, Guanjun Qiao, Wen Li, Jinhai Si and Xun Hou, Wetting characteristics on hierarchical structures patterned by a femtosecond laser, J. Micromech. Microeng., 20, 075029 (2010).
 Hewei Liu, Feng Chen*, Xianhua Wang, Qing Yang, Hao Bian, Jinhai Si and Xun Hou, Influence of liquid environments on femtosecond laser ablation of silicon, Thin Solid Films, 518, 5188 (2010).


 Xianhua Wang, Feng Chen, Qing Yang, Hewei Liu, Hao Bian, Jinhai Si and Xun Hou, Fabrication of quasi-periodic micro-voids in fused silica by single femtosecond laser pulse, Appl. Phys. A, 101, 6063 (2011).


 Xianhua Wang, Feng Chen, Weiwei Liang, Hewei Liu, Qing Yang, Jinhai Si and Xun Hou, Femtosecond laser induced mesoporous structures on silicon surface, Opt. Commun., 284, 317 (2011).


 Guangqing Du, Qing Yang, Feng Chen, Jinhai Si and Xun Hou, Insight into the thermionic emission regimes under gold film thermal relaxation excited by a femtosecond pulse, Appl. Surf. Sci., 257, 9177 (2011).


 Guangqing Du, Feng Chen, Qing Yang, Jinhai Si and Xun Hou, Ultrafast thermalization characteristics in Au film irradiated by temporally shaped femtosecond laser, Opt. Commun., 284, 640 (2011).


 X. Wang, F. Chen*, H. Liu, W. Liang, Q. Yang, Jinhai Si and X. Hou, Fabrication of micro-gratings on Au-Cr thin film by femtosecond laser interference with different pulse durations, Appl. Surf. Sci., 255, 8483 (2009).


 Weiwei Liang, Feng Chen *, Hao Bian , Qing Yang , Hewei Liu , Xianhua Wang, Jinhai Si and Xun Hou, Periodic surface nanostructures on polycrystalline ZnO induced by femtosecond laser pulses, Opt. Commun., 283, 2385 (2010).


 Guangqing Du, Feng Chen*, Qing Yang, Jinhai Si and Xun Hou, Ultrafast temperature relaxation evolution in Au film under femtosecond laser pulses irradiation, Opt. Commun., 283, 1869 (2010).


 H. Liu, F. Chen*, X. Wang, Q. Yang, D. Zhang, Jinhai Si and X. Hou, Photoetching of spherical microlenses on glasses using a femtosecond laser, Opt. Commun., 282, 4119 (2009).