发表文章

1.       Yang Z., Sun N., Cheng R., Zhao C. Y., Liu Z., Li X., Liu J. and Tian Z. M. pH multistage responsive micellar system with charge-switch and PEG layer detachment for co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells (2017). Biomaterials, 147: 53-67.   IF: 8.806

 

2.      Yang Z., Cheng R., Zhao C., Sun N., Luo H., Chen Y., Liu Z., Li X., Liu J., Tian Z. M. Thermo-and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors (2018). Theranostics, 8: 4097-4115. IF:8.537

 

3.       Yang Z., Luo H., Cao Z., Chen Y., Gao J., Li Y., Jiang Q., Xu R. and Liu J. Dual-targeting hybrid nanoparticles for the delivery of SN38 to Her2 and CD44 overexpressed human gastric cancer (2016). Nanoscale, 8: 11543–11558. IF: 7.760

 

4.     Yang Z., Jiang Z.Z., Cao Z., Zhang C., Gao D., Luo X.G., Zhang X.F., Luo H.Y., Jiang Q. and Liu J. Multifunctional non-viral gene vectors with enhanced stability, improved cellular and nuclear uptake capability, and increased transfection efficiency (2014). Nanoscale, 6:10193-10206.  IF: 7.367

 

5.     Yang Z., Tang W.X., Luo X.G., Zhang X.F., Zhang C., Li H., Gao D., Luo H.Y., Jiang Q. and Liu J. Dual-Ligand Modified Polymer-Lipid Hybrid Nanoparticles for Docetaxel Targeting Delivery to Her2/neu Overexpressed Human Breast Cancer Cells (2015). Journal of Biomedical Nanotechnology, 11:1401-1417.  IF: 7.578

 

6.       Yang Z., Zhang X.F., Luo X.G., Jiang Q., Liu J., and Jiang Z.Z. Enzymatic Synthesis of Poly(butylene-co-sebacate-co-glycolate) Copolyesters and Evaluation of the Copolymer Nanoparticles as Biodegradable Carriers for Doxorubicin Delivery (2013). Macromolecules, 46:1743-1753.  IF: 5.927

 

7.      Yang Z., Sun N., Cheng R., Zhao C. Y., Liu J. and Tian Z. M. Hybrid nanoparticles coated with hyaluronic acid lipoid for targeted co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells (2017). Journal of Materials Chemistry B, 5: 6762-6775.   IF:4.776

 

8.       Sun N., Zhao C., Cheng R., Liu Z., Li X., Lu A., Tian Z. M.*, Yang Z.*(Correspondence author) Cargo-free nano-medicine with pH-sensitivity for co-delivery of DOX conjugated prodrug with SN38 to synergistically eradicate breast cancer stem cells (2018). Molecular Pharmaceutics, DOI: 10.1021/acs.molpharmaceut.8b00367 IF:4.556

 

9.      Yang Z., Gao D., Cao Z., Zhang C., Cheng D., Liu J. and Shuai X.T. Drug and gene co-delivery systems for cancer treatment (2015). Biomaterials Science, 3:1035-1049.  IF:4.210

 

10.     Yang Z.Li Y.Q.Gao J.B.Cao Z.Jiang Q. and Liu J.pH and redox dual-responsive multifunctional gene delivery with enhanced capability of transporting DNA into the nucleus (2017)Colloids and Surfaces B: Biointerfaces153:111-122.  IF: 3.887

 

11.    Wang Y., Yang P.F., Zhao X. R., Gao D., Tian Z.M., Ma T. Y. and Yang Z.* (Correspondence author) Multifunctional Cargo-Free Nanomedicine for Cancer Therapy (2018). International Journal of Molecular Sciences, 19: E2963. IF:3.687

 

12.    Zhao C., Cheng R., Yang Z.* (co-correspondence author), Tian Z. M.* Nanotechnology for Cancer Therapy Based on Chemotherapy (2018). Molecules, 23:826  IF:3.098

 

13.    Zheng X.W., Li X.X., Chen M., Yang P.F., Zhao X.R., Zeng L., OuYang Y.N., Yang Z.* (co-correspondence author) and Tian Z.M.* The protective role of hawthorn fruit extract against high salt-induced hypertension in Dahl salt-sensitive rats: impact on oxidative stress and metabolic patterns (2019). Food & Function, 2019,10, 849-858.   IF:3.289

 

14.     Yang Z., Luo X.G., Zhang X.F., Liu J. and Jiang Q. Targeted delivery of 10-hydroxycamptothecin to human breast cancers by cyclic RGD-modified lipid–polymer hybrid nanoparticles (2013). Biomedical Materials, doi:10.1088/1748-6041/8/2/025012.  IF:2.469

 

15.    Luo H.Y.#, Yang Z.# (Co-first author), Wei W.#, Li Y.Q., Pu H.Y., Chen Y., Sheng H., Liu J. Xu R.H. Enzymatically synthesized poly(amino-co-ester) polyplexes for systemic delivery of pcDNA-miRNA-214 to suppress colorectal cancer liver metastasis (2018). Journal of Materials Chemistry B, 6, 6365-6376. IF:4.776

 

申请国家发明专利

1. 杨哲,田中民,赵晨阳,孙娜,程瑞。 《pH响应型无载体纳米药物制剂及制备方法、应用》 2017,国家发明专利,专利申请号:201710543363.3

2.杨哲田中民程瑞赵晨阳孙娜。《高临界相转变温度及pH双响应型“化疗-光热协同治疗”纳米粒子的制备方法及应用》2018,国家发明专利,专利申请号:201710731901.1

3.刘杰,蒋庆,杨哲。《一种靶向复合型纳米粒子的制备方法》 2013,国家发明专利,授权专利号:201210259694.1


4. 刘杰,杨哲,骆卉妍,蒋庆,徐瑞华,李颖琴。《一种负载7-乙基-10-羟基喜树碱的双靶向复合纳米粒子及其制备方法和应用》2015,国家发明专利,授权专利号:201510027285.2


5. 刘杰,蒋庆,杨哲,路振平,甘盛龙。《一种聚乳酸-羟基乙酸共聚物纳米药物载体及其制备方法和应用》2014,国家发明专利,授权专利号:201410212594.2


6. 刘杰,蒋庆,罗新根,舒雅俊,杨哲。《一种集成式多功能微纳样品制备装置》2013,国家发明专利,授权专利号:201310540178.0

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