基本信息

 

 

个人简历

2001.7~今,西安交通大学生命科学与技术学院,博士,副教授

1998~2001,陕西师范大学生命科学学院,硕士

1995~1998,西安财经学院旅游系,讲师

1991~1995,西北轻工业学院食品系,学士

联系方式

 yar.lee@mail.xjtu.edu.cn

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研究领域

主要研究领域

糖生物学

天然产物功能研究

 
近三年的科研项目情况

 

 主持国家自然科学基金青年基金项目1项:硫酸酯壳聚糖对胰岛β细胞氧化损伤的保护作用及其机制研究(项目负责人,项目编号No. 311012662012-2014
 主持陕西省自然科学基础研究计划项目1项:壳聚糖衍生物对胰岛β细胞氧化损伤的作用(项目负责人,项目编号No. 2011JM40252011-2013
主持西安交通大学前沿新兴、交叉项目1项:壳聚糖衍生物对胰岛β细胞氧化损伤的抑制作用及机制(项目负责人,项目编号No. 308010592011-2013

 

科研论文

1.         Xiao-Yun Lu, Hui Guo, Lijun Sun, Liyu Zhang, Ya-Li Zhang(Corresponding author). Protective effects of sulfated chitooligosaccharides with different degrees of substitution in MIN6 cells International Journal of Biological Macromolecules, (SCI). 
3.         Ya-Li Zhang, Xiao-Yun Lu, Qian-Qian Liu, Ming-Chuan Li, Zhi-Qian Yang, Jian-Gang Ma. Production and Characterization of Poly(ethylene glycol) Modified Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) with Flexible Molecular Weight. Chinese Journal of Polymer Science, (SCI) 2012(30):1-11.
4.         Hao XuYali Zhang, Junqing Sun, Jinhong Wei, Lijun Sun, Jianbao Zhang. The effect of distinct sources of Ca2+ on cardiac hypertrophy in cardiomyocytesExperimental Biology and Medicine (SCI), 2012, 237(3):271-8.
5.         Yali Zhang, Xiaoyun Lu, Zhongbin Fu, Zibao Wang, Jianbao Zhang. Sulfated modification of a polysaccharide obtained from fresh persimmon (Diospyros kaki L.) fruit and antioxidant activities of the sulfated derivatives [J]. Food Chemistry (SCI) 2011, 127: 10841090.
6.         Lijun Sun, Jianbao Zhang, Xiaoyun Lu, Liyu Zhang, Yali Zhang (Corresponding author).Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves, Food and Chemical Toxicology, (SCI) 2011(49) :2689-2696.
7.         Xiao-Yun Lu, Hui Guo, Ya-Li Zhang (Corresponding author). Protective effects of sulfated chitooligosaccharides with different degrees of substitution against hydrogen peroxide -induced damage in MIN6 Cells, International Journal of Biological Macromolecules, (SCI) 2011, 82:52-58. 
8.         Yali Zhang, Xiaoyun Lu, Yuning Zhang, Liguo Qin, Jianbao Zhang. Sulfated modification and immunomodulatory activity of water-soluble polysaccharides derived from fresh Chinese persimmon fruit [J]. International Journal of Biological Macromolecules, (SCI) 2010,46(1):67-71.   
9.         Yali Zhang, Jianbao Zhang, Xiaoyan Mo, Xiaoyun Lu, Yuning Zhang, Liguo Qin. Modification, characterization and structure–anticoagulant activity relationships of persimmon polysaccharides [J]. Carbohydrate Polymers (SCI) 2010, 82:515-520. 
10.     Xiaoyun Lu, Yali Zhang, Liang Wang. Preparation and in vitro Drug-Release Behavior of 5-Fluorouracil-Loaded Poly(hydroxybutyrate-co-hydroxyhexanoate) micro- and nanoparticles [J]. Journal of Applied Polymer Science (SCI)2010,116(5):2944–2950   
11.     Xiao-Yun Lu, Elisa Ciraolo, Rachele Stefenia, Guo-Qiang Chen & Yali Zhang & Emilio Hirsch Sustained release of PI3K inhibitor from PHA nanoparticles and in vitro growth inhibition of cancer cell lines[J]. Appl Microbiol Biotechnol (SCI), 2011, 89:1423–1433  
12.     LI Guang, ZHANG Yali, LIANG Huaxiang. Optimization of isoflavones extraction assisted by ultrasound from soybean dregs using response surface methodology. Food Science and Technology, 2008,(2):144-148
13.      ZHANG Ya-li, MEI Jian-sheng, Yue Jie. The inhibition of persimmon extracts on Bacillus subtilis Science and Technology of Food Industry,2007,(2):133-136
14.     Guo Hui,Zhang yali,Wang Shumei, Shi Bingyin,et al.The evaluation of insulin resistance and β-cell function in patients with systemic lupus erythematosus.Journal of Xi'an Jiaotong University(Medical Sciences).2006,276):569-571
15.     ZHANG Ya-li, MEI Jian-sheng, ZHANG Mei-yue. Study on extraction and stability of yellow pigment from the fruit of persimmon. Food Science and Technology. 2006,(10)148-152
16.     Zhang yali, Guo Hu Tian Zhongmin. The research on persimmon pharmacological effect and its clinical application. Chinese Traditional Patent Medicine. 2006. (5):720-722
17.     MEI Jian-sheng, ZHANG Ya-li, YU Shuai. Correlative Analysis and Detection of the Glucose Concentration between Salivary and Blood of Patients. Acta Laser Biology Sinica. 2006(1):94-96
18.     Zhang yali, Zhang Wenjuan, He Qionghua. The method of Trypsin combined with Sevag extract polysaccharides protein from persimmon. Science and Technology of Food Industry, 2005(5):107-108
19.     Zhang yali, Guo Hui.Research on the Material Foundation of Blood-tonifying Action of Jujuba Bates.Food and Nutrition in China.2005(2) .
20.     ZHANG Ya-li, CHEN Jin-ping, LI Jian-ke. Effects of jujuba dates juice on hyperlipidaemia mice. Journal of Henan Agricultural University,. 2004(1):116-118
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