基本信息

  

成瀛  博士

副教授, 博士生导师

 

研究方向:

1. 中枢神经系统和外周组织对能量稳态调控的研究

2. 线粒体与复杂代谢疾病的研究

3. 造血干细胞和血液肿瘤的研究

 

 

联系方式

电话:

Email:yingchengxjtu.edu.cn

通讯地址:

陕西省西安市咸宁西路28号

西安交通大学生命科学与技术学院

710049

                 

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刘健康教授
中科院营养所
PENN medical school
CHOP
欢迎报考

 

 

欢迎有志于投身代谢疾病和血液肿瘤疾病研究的优秀学子报名联系!

 

 

教育经历

2000-2004  西安交通大学生命科学与技术学院,  学士

2004-2010  中国科学院上海营养科学研究所,  博士

2011-2016  美国宾夕法尼亚大学医学院、费城儿童医院, 博士后

2016-2017  美国 费城儿童医院,  Research Associate

2017-至今   西安交通大学生命科学与技术学院, 副教授

荣誉称号

2016  Postdoctoral Fellow Award from University of Pennsylvania School of Medicine and the Children’s Hospital of Philadelphia, USA.

2015   上海市科技进步奖三等奖

2012-2014    Postdoctoral fellowship from American Heart Association

 

论文发表

  1. Kim, E., Cheng, Y., Bolton-Gillespie, E., Cai, X., Ma, C., Tarangelo, A., Le, L., Jambhekar, M., Raman, P., Hayer, K.E., et al. (2017). Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression. The Journal of experimental medicine 214, 1901-1912. (IF=11.2, 一区期刊)

  2. Lv, K., Jiang, J., Donaghy, R., Riling, C.R., Cheng, Y., Chandra, V., Rozenova, K., An, W., Mohapatra, B.C., Goetz, B.T., et al. (2017). CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies. Genes & development 31, 1007-1023. (IF=10.0,一区期刊)

  3. Cheng, Y., Chikwava, K., Wu, C., Zhang, H., Bhagat, A., Pei, D., Choi, J.K., and Tong, W. (2016). LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors. The Journal of clinical investigation 126, 1267-1281. (IF=13.3,  一区期刊, Medicine category: 26th out of 6537)

  4. Zhang, Q., Liu, B., Cheng, Y., Meng, Q., Xia, T., Jiang, L., Chen, S., Liu, Y., and Guo, F. (2014). Leptin signaling is required for leucine deprivation-enhanced energy expenditure. The Journal of biological chemistry 289, 1779-1787. (IF=4.6,二区期刊)

  5. Jiang, J., Balcerek, J., Rozenova, K., Cheng, Y., Bersenev, A., Wu, C., Song, Y., and Tong, W. (2012). 14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells. The Journal of clinical investigation 122, 2079-2091. (IF=13.3,一区期刊)

  6. Xia, T., Cheng, Y., Zhang, Q., Xiao, F., Liu, B., Chen, S., and Guo, F. (2012). S6K1 in the central nervous system regulates energy expenditure via MC4R/CRH pathways in response to deprivation of an essential amino acid. Diabetes 61, 2461-2471. (IF=8.8,一区期刊)

  7. Cheng, Y#., Zhang, Q#., Meng, Q., Xia, T., Huang, Z., Wang, C., Liu, B., Chen, S., Xiao, F., Du, Y., et al. (2011). Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system. Molecular endocrinology 25, 1624-1635. ( IF=4.7,二区期刊,#共同一作)

  8. Xiao, F., Huang, Z., Li, H., Yu, J., Wang, C., Chen, S., Meng, Q., Cheng, Y., Gao, X., Li, J., et al. (2011). Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways. Diabetes 60, 746-756. (IF=8.8,一区期刊)

  9. Cheng, Y#., Meng, Q#., Wang, C., Li, H., Huang, Z., Chen, S., Xiao, F., and Guo, F. (2010). Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue. Diabetes 59, 17-25. (IF=8.8, 一区期刊,Medicine category : 79th out of 6537, #共同一作)

  10. Wang, C., Huang, Z., Du, Y., Cheng, Y., Chen, S., and Guo, F. (2010). ATF4 regulates lipid metabolism and thermogenesis. Cell research 20, 174-184. (IF=12.4,一区期刊)

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