课题组在揭示多重耐药鲍曼不动杆菌响应调控因子AdeR识别药物外排泵AdeABC顺反子序列及激活的基础上（Wen et al.2017 Nucleic Acids Research)，进一步阐明AdeR的N端intrinsically disordered region 通过蛋白酶体降解途径以及该二元调控系统中膜表面组氨酸激酶受体AdeS可通过多聚的形式调控药物外排泵的活性。该成果以“Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS”为题在Cell子刊iScience发表。温玉荣教授为该论文的Lead Contact