Basic Information


Xinhan Zhao, Ph.D., M.D.
Professor
Physician in Charge
Medical Oncologist
Doctor Supervisor
Post-doctor Supervisor

 

 

Working experience

1988-present   Department of medical oncology, No.1 Hospital affiliated to School of Medicine, Xi’an Jiaotong University. Chief physician, Professor, Supervisor of Ph.D Candidates.

Teaching

               Undergraduate Teaching：Introduction to Oncology
  Postgraduate Teaching：The Basical Science of Oncology, Clinical Oncology,Progress in Clinical Oncology.
 Ph.D.   M.D.:     The Basical Science of Oncology, Progress in Clinical Oncology 

Contact

Department of medical oncology

No. 1 Hospital affiliated to School of Medicine,

Xi’an Jiaotong University, Xi’an, China, 710061
Tel: 86-29-85324136

Fax: 86-29-82655299
E-mail: zhaoxinhan@mail.xjtu.edu.cn

 

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Research fields

1.Target-gene therapy of carcinoma
2.Multi-drug resistance of carcinoma
3.Multi-disciplinary management of carcinoma

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Education

            

         09/2000-06/2004     Ph. D. in Internal Medicine, School of Medicine, Xi’an Jiaotong University.

         09/1990-07/1993       Master in Oncology, Department of oncology, the former Xi’an Medical University.

         09/1983-07/1988        Bachelor in Clinical Medical Science, the former Xi’an Medical University.

 

 

Scientific research and awards

1.      PRM complex against breast cancer screening and molecular peptide specificity and function transformation. National Scientific Foundation Committee.( No：30772112).

2.   Study on anti-angiogenetic effect in breast carcinoma by G4PAMAM/VEGFASODN.

       National Scientific Foundation Committee. (No: 30572140).

3.     Arsenic magnetic nanoparticles targeting therapy microspheres gastric cancer and lymph node metastases. Scientific and technologic Key Research Fund Project of Shaanxi Province. (No：2005 K09-G32005).

4.      Study on Test and Clinical Meaning of Minor Marrow Metastasis Focus of Mammary Cancer. Shaanxi Public Health Department Fund Project through Successful Biding in June 1998.( No：98054).

 5.      Study on Clinical Application of Lymphadenectomy of Sentry of Early Stage Mammary     Cancer.   Scientific Key Research Fund Project of Shaanxi Province through Successful Biding in September 2000. (No：2000 K14-G11).

6.      Study on Change of ER Positive Phaenotype Gene of Gastric Carcinoma. Research Fund Project of No. 1 Attached Hospital of Xi’an Medical University through Successful Biding in October 1995. (No：YK 200011).

7.      Molecular Mechanism of BCL-2 Introduced by Caspase-3 in multi-drug resistance to Leukemia. Research Fund Project of No. 1 Attached Hospital of Xi’an Medical University through Successful Biding in November 2000. (No：YK 200011).

8.      Basic and Clinical Research on Large Dose Chemotherapy Supported by Peripheral General Blood Dry Cell. Shaanxi Public Health Department Successful Biding Research Project through Successful Biding in June 1999.( No：99046).

9.      Basic and Clinical Research on Relevant Gene of Tumor. Key Cultivation Project of Action Plan of Xi’an Jiaotong University. (October 2000).

10.      Research on Drug Resistance Mechanism for Incretion Treatment of Mammary Cancer. Research Project of Shaanxi Public Health Department through Successful Biding in June 1996. (No：99038).

11.  Construction of DC Bacterin of Gastric Carcinoma Jointly Modified by Gene and Study on Anticancer Mechanism. Key Research Project of Shaanxi Province through Successful Biding in 2002. (2002K10-G4).

12.  Proliferation and apoptosis influence of MAPKdsRNA on a variety of tumor cell. On-the-job Ph.D Fund Project of No. 1 Attached Hospital of School of Medicine of Xi’an Jiaotong University.( No: Bjj2004118).

13.  Research of gene change on ER negative  phenotype of Stomach cancer. Research Fund Project of No. 1 Attached Hospital of Xi’an Medical University through Successful Biding in october1995. (No:YK 9512).

14.  Research of Oxaliplatin /folic acid calcium / 5 - fluorouracil  hour chemotherapy treatment on advanced colorectal cancer. The new medical technology project of No. 1 Attached Hospital of school of medicine of Xi’an Jiaotong University. (2005).

15.  Clinical research of Electricity perforation chemotherapy to malignant tumor. The new medical technology project of No. 1 Attached Hospital of school of medicine of Xi’an Jiaotong University. (2006).

16.  Clinical evaluation of chemotherapy and hormone therapy on adanced gastric. Second-class reward in science and technology progress in high school of Shaanxi province. (2006).

17.  Comparative study of EAP and improvement EAP in the treatment effect to middle-late gastric cancer. Third-class reward in science and technology progress in high school of Shaanxi province.( 2001).

18.  Oncology of genitourinary system of male. Third-class reward in science and technology progress in high school of Shaanxi province. (2002).

19.  Molecules resolve of cancer stem cells and specific therapeutic development team. "985 project" second phase and biomedical technology innovation construction platform of Xi ’an Jiaotong university. (2005).

 

PUBLICATIONS

    

 

1．XH Zhao, HG Tian, X Ma, Li L. Epigallocatechin gallate, the main ingredient of green tea induces apoptosis in breast cancer cells. Frontiers in Bioscience，2006; 9(11)：2428-2433.    SCI indexed（IF＝2.623）.

2． XH Zhao, L Li, ZY Wang. Chemoprevention of breast cancer: current status and future prospects. Frontiers in Bioscience，2006; 9(1)：2249-2256. SCI indexed（IF＝2.623）.

3． XH Zhao, SZ Gu, SX Liu, BR Pan. Expression of estrogen receptor and estrogen receptor mRNA in gastric carcinoma tissues. World Journal of Gastroenterology，2003; 9(4)：665-669. SCI indexed（IF＝3.318）

4． XH Zhao, SZ Gu, HG Tian, P Quan, BR Pan. Clinical significance of expression of apoptotic signal proteins in gastric carcinoma tissues. World Journal of Gastroenterology，2005; 11(25)：3846-3849. MI indexed.

5． SZ Gu, XH Zhao, P Quan, SB Li, BR Pan. Alterations of serum cholinesterase in patients with gastric cancer. World Journal of Gastroenterology，2005; 11(29)：4604-4606. MI Indexed.

6.  XH Zhao, J Li, LL Li, X Ma, HG Tian, SX Liu. Role of Bcl-2-related anti-apoptosis mechanism in drug resistance of leukemia. J Fourth Mil Med Univ. 2005; 26(23): 2192-2194.

7.  XH Zhao, ZY Wang, J Li, P Quan. Bcl-2 antisen oligodeoxynucleotides to enhance the apoptosis-inducing effect of artesunate on K562 cells. J Fourth Mil Med Univ.  2006; 27(14): 1282-1285.

8.  XH Zhao, ZY Wang, J Li, L Li. Quercetin-induced apoptosis of human leukemia K562 cells. J Fourth Mil Med Univ. 2006; 27(15): 1395-1398.

9.  XH Zhao.Correlation of expression of estrogen receptor, progestogen receptor and c-erbB-2 in breast carcinoma with the clinicopathological fetures. J Fourth Mil Med Univ.  2006; 27(17): 1580-1583.

10. XH Zhao, TJ Qin, JX Xiao, XJ Xiao, SX Liu. The clinical evaluation on chemo-endocrine therapy for advanced gastric carcinoma. J. Xi’an Med. Univ., (Medicine Sciences). 2003; 24(6): 608-610.

11.  XH Zhao, HG Tian, P Quan, SX Liu. Correlation between drug resistance of leukemic cells and Caspase-3. J. Xi’an Med. Univ., (Medicine Sciences). 2005; 26(5): 463-469.

12. XH Zhao, X Ma, LL Li, J Li, SX Liu. Expression of Caspase-3 and Bcl-2 in leukaemia cell apoptosis and its significance in multiple-drug resistance. J. Xi’an Med. Univ., (Medicine

Sciences). 2005; 26(6): 581-585.

13. XH Zhao, X Ma,. Assessment on efficacy of adjuvant intraperitoneal chemotherapy on advanced gastric carcinoma after radical treatment. J modern oncol, 2005; 13(6): 791-794.

14. XH Zhao, P Quan, J Li, HG Tian, SX Liu. Research on the cell apoptosis of leukemia induced by arsenic sulfide. J modern oncol, 2006; 14(1): 88-90.

15. XH Zhao, HG Tian. Molecular targeted therapy of tumors. J modern oncol,2005; 13(1)：133-136.

16. XH Zhao, X Ma. Research advancement of the chrono-chemotherapy in advanced colorectal carcinoma. J modern oncol, 2005; 13(4): p4－5.

17. XH Zhao, SZ Gu,SX Liu, R Li. Fundamental and Clinical Research of  Multi-drug Resistance with Malignancies. China Oncology. 2003; 12(1): 34-36.  

18. TJ Qin, XH Zhao, J Yun, LX Zhang, ZP Ruan, BR Pan. Efficacy and safety of gemcitabine-oxaliplatin combined with huachansu in patients with advanced gallbladder carcinoma. World Journal of Gastroenterology, 2008; 14（33）:5210-5216. SCI indexed（IF＝3.318）.

19. XH Zhao, ZY Wang, LL Li, L Li, XH Li. The study of expression changes of ERα and ERβ during breast cancer cell apoptosis induced by Tamoxifen. J. Zhejiang Univ. (Medical Sciences), 2008; 37（3）：276-282 . MI Indexed.

20. XH Zhao, L Li, ZY Wang, LX Zhang, GL An.Anti-angiogenesis effect of G4PAMAM/VEGFASODN on breast cancer in vitro. J. Zhejiang Univ. (Medical Sciences), 2008; 37(6): 612-621.  MI Indexed.

21.  XH Zhao, F Tian. Research status and prospects of tumor angiogenesis inhibitors. J modern oncol,  2008; 16(11): 2004-2006.

22.  SZ Gu, XH Zhao, LX Zhang, L Li, ZY Wang, M Meng, GL An. Anti-angiogenesis effect of generation 4 polyamidoamine/vascular endothelial growth factor antisense oligodeoxynucleotide on breast cancer in vitro, J. Zhejiang Univ. B 2009 10(3): 159-167 SCI indexed

23. XH Zhao, L Li, ZY Wang, LX Zhang, GL An. Anti-angiogenesis effect of G4PAMAM/VEGFASODN on breast cancer in vitro, Oncology Reports 2009 SCI indexed

24. XH Zhao, F Tian, ZY Wang.  Research status and prospects of cancer gene therapy vectors. J modern oncol. 2007,; 15(12): 1879-1882.

 

Monograph Published

1.      “Oncology of Masculine Urogenital System”. Deputy Chief Editor. Shaanxi Science and Technology Press. 1998.8.

2.      “Diagnosis and Treatment of Malignant Lymphoma”. Editor. Joint Press of Beijing Medical University and China Xiehe Medical University. 1997.11.

3.      “New Advances of Research in the Field of Modern Clinical Surgery”. Editor. China

             Medical Science and Technology Press. 1996.1.

4.      “Modern Drug Treatment of Tumor”. Member of Editing Committee. World Library

Press. 2002.2.

5.      “Oncology of General Surgery”. Member of Editing Committee. People’s Military Medical Press. 2005.1.

6.      “Modern Internal Medical Treatment of Tumor”. Chief Editor. World Library Press. 2003.12.

7.      “Differentiation and Apoptosis of cancer “. Editor. Shaanxi Science and Technology Press. 2005,7.

8.      “Molecular Targeted Therapy of Cancer”. Editor. People’s medical publishing house. 2007.12.

9.      “Treatment of Tumor with Complications and Emergency”. Editor. Shaanxi Science and Technology Press. 1995.4.

10.  “Multidisciplinary Integrated Treatment of Tumor”. Chief Editor. The Fourth Military Medical University Press. 2008.10.