Dr. Min Lin is a full professor in the School of Life Science and Technology at Xi’an Jiaotong University. Dr. Lin achieved B.S. degree (2005) in Material Science and Engineering from Hefei University of Technology and M.S. degree (2008) in Material Science and Engineering from Xi’an Jiaotong University. Dr. Lin completed his Ph.D. degree in Mechanics at Xi’an Jiaotong University in 2011. He joined the faculty of Xi’an Jiaotong University in 2011. During 2014-2015, Dr. Lin worked as a research fellow at Harvard Medical School and Massachusetts General Hospital. Dr. Lin’s current research interest lies in the mechanobiology of cells, with a focus on force-sensitive receptor-ligand interactions, and the subsequent development of mechanical forces in cells, and theoretical models for cell mechanosensing.

Living cells often respond to mechanical cues from their surrounding extracellular matrix or adjacent cells thus dictate their fates, a process called cellular mechanotransduction. These mechanosensing arises from integrated information from the membrane-localized receptors that bind ligands present on another cell or the extracellular matrix. This introduces a number of physical effects including spatial organization of receptor-ligand complexes and development of mechanical forces in cells. The transmission of force over space and time and their conversion into biochemical signals that initiate cellular pathology and physiology. Dr. Lin’s current research interest lies in the mechanobiology of cells, with a focus on force-sensitive receptor-ligand interactions, and the subsequent development of mechanical forces in cells, and theoretical models for cell mechanosensing.

Personal key words:  Cellular Mechanotransduction，Cellular microenvironment, Receptor-ligand interaction，Computational model.