(1.)Basic Information

Jia Liu, Ph.D., Associate professor

 

Research area: The regulatory roles of E3 ubiquitin ligases in cardiovascular diseases and metabolic diseases.

 

(2.)Positions

·Oct. 2019 - Now    

    Associate professor，School of Basic Medical Sciences, Xi’an Jiaotong University

 

·Oct. 2015 - Sep. 2019 

    Assistant professor，School of Basic Medical Sciences, Xi’an Jiaotong University

(3.)Education

·Sep. 2010 - Oct. 2014

Graduate study in Xi’an Jiaotong University, School of Life Science and Technology

 · Major: Biochemistry and Molecular Biology   · Degree: Doctor of Science

·Nov. 2011 - Nov. 2013

Exchange study in Beth Israel Deaconess Medical Center, Harvard Medical School

·Mar. 2009 - Aug. 2010

Technician of the Institute of Mitochondrial Biology and Medicine, Xi’an Jiaotong University

·Sep. 2006 - June. 2008

Graduate study in Veterinary Medicine College, Northwest A & F University.

· Major: Developmental Biology              · Degree: Master of Science         

·Sep. 2002 - July. 2006

Undergraduate study in Life Science College, Northwest A & F University.

                      · Major: Biotechnology                    · Degree: Bachelor of Science  

(5.)Scientific Research

(1) Jia Liu; Qinyu Yao; Xinya Xie; Qi Cui; Tingting Jiang; Ziwei Zhao; Xiong Du; Baochang Lai; Lei Xiao; Nanping Wang; Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism, Nutrients, 2022, 14(9):1756

 

(2) Liu, Jia; Yao, Qinyu; Xiao, Lei; Ma, Wen; Li, Fan; Lai, Baochang; Wang, Nanping; PPAR gamma induces NEDD4 gene expression to promote autophagy and insulin action, FEBS Journal, 2020, 287(03): 529-545 


(3) Liu, Jia; Yao, Qinyu; Xiao, Lei; Li, Fan; Ma, Wen; Zhang, Zihui; Xie, Xinya; Yang, Chunmiao; Cui, Qi; Tian, Ying; Zhang, Chao; Lai, Baochang; Wang, Nanping; APC/Cdh1 targets PECAM-1 for ubiquitination and degradation in endothelial cells, Journal of Cellular Physiology, 2020, 235(3): 2521-2531 

 

(4) Rui Shao#, Jia Liu#, Guang Yan, Jinfang Zhang, Yujiao Han, Jianfeng Guo, Zhan Xu, Zhu Yuan, Jiankang Liu, Marcos Malumbres, Lixin Wan*, Wenyi Wei*, Weiguo Zou*, Cdh1 regulates craniofacial development in part via APC-dependent activation of goosecoid, Cell Research, 2016, 26(6): 699-712.

 

(5) Jia Liu#, Lixin Wan#, Jing Liu, Zhu Yuan, Jinfang Zhang, Jianfeng Guo, Marcos Malumbres, Jiankang Liu*, Weiguo Zou*, Wenyi Wei*, Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner, Cell Discovery, 2016 Feb 2;2: 15044.

 

(6) Jia Liu#, Ying Tang#, Zhihui Feng, Chen Hou, Hui Wang, Jiong Yan, Jing Liu，Weili Shen，Weijin Zang, Jiankang Liu*, Jiangang Long*, Acetylated FoxO1 mediates high-glucose induced autophagy in H9c2 cardiomyoblasts: regulation by a polyphenol-(-)-epigallocatechin-3-gallate, Metabolism-Clinical and Experimental, 2014, 63(10): 1314-1323.

 

(7) Jia Liu#, Ying Tang#, Zhihui Feng, Jing Liu, Jiankang Liu*, Jiangang Long*, (-)-Epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto-Kakizaki rats, Free Radical Research, 2014, 48(8): 898-906.

 

(8) Jia Liu#, Lixin Wan#, Pengda Liu#, Hiroyuki Inuzuka, Jiankang Liu, Zhiwei Wang*, Wenyi Wei*, SCF(beta-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway, Oncotarget, 2014, 5(4): 1026-1037.

(7.)Contact

E-mail：Jeven_liu@xjtu.edu.cn

WeChat：jeven_liu

Address：76 Yanta Road W., Kejiao building, Room 602, Xi'an, Shaanxi 710061, China