主要研究领域为衰老及肿瘤的蛋白翻译后调控机制，生物标志物及靶向药物筛选，为衰老相关疾病的诊断和治疗提供基础。主持国家自然科学基金青年项目，陕西省自然科学基金青年项目，中国博士后基金面上项目，校企合作项目等。以（共同）第一作者在Cell Research, Oncogenesis, FRBM发表SCI收录期刊7篇，参与多篇论文的发表。申请和授权发明专利2项，担任中国生物物理学会青年会员，陕西省食品学会会员。

研究方向：

1. 肿瘤和衰老相关疾病中线粒体蛋白质翻译后修饰的作用机制及靶向药物研究。

2.肠道微生物在衰老相关疾病中的作用机制及靶向肠道菌群改善衰老相关疾病的药物筛选。

科研论文：

Sun Qiong^#; Shi Le^#; li Shuaijun; Li Jialu; Zhang Ruifen; Huang Xinghai; Shao Yongping; Feng Zhihui; Peng Yunhua; Yang Zhiwei; Liu Jiankang; Liu Huadong*; Long Jiankang*; PET117 assembly factor stabilizes translation activator TACO1 thereby upregulates mitochondria-encoded cytochrome C oxidase 1 synthesis, Free Radical Biology and medicine, 2023, 205: 13-24.

Liang Bing^#; Shi Le^#; Du Dongyue^#; Li Hua; Yi Ning; Xi Yue; Cui Jianjiao; Li Ping; Kang Hongbin; Mami Noda; Sun Xuejun; Liu Jiankang*; Qin Shucun*; Long Jiangang*; Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study, Antioxidants, 2023, 12(6): 1245.

Liu Jing^#; Peng Yunhua^#; Shi Le^#; Wan Lixin; Inuzuka Hiroyuki; Long Jiangang; Guo Jianping; Zhang Jinfang; Yuan Min; Zhang Shuangxi; Wang Xun; Gao Jing; Liu Jiankang*; Wei Wenyi*; Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle, Cell Research, 2021, 31(1): 80-93.

Shi Le; Liu Jing; Peng Yunhua; Zhang Jinfang; Dai Xiangpeng; Zhang Shuangxi; Wang Yongyao; Liu Jiankang^*; Long Jiangang^*; Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission, Molecular Oncology, 2020, 14(12): 3169-3183.

Shi Le; Du Dongyue; Peng Yunhua; Liu Jiankang*; Long Jiangang*; The functional analysis of Cullin7 E3 ubiquitin ligases in cancer, Oncogenesis, 2020, 9(10): 98.

Shi Le; Zhao Daina; Hou Chen; Peng Yunhua; Liu Jing; Zhang Shuangxi; Liu Jiankang^*; Long Jiangang^*; Early interleukin-6 enhances hepatic ketogenesis in APPSWE/PSEN1dE9 mice via 3-hydroxy-3-methylglutary-CoA synthase 2 signaling activation by p38/nuclear factor κB p65, Neurobiology of Aging, 2017, 56: 115-126.

Shi Le^#; Lei Zhanjun^#; Zhao Congying; Lv Xiaoxing; Jiang Li; Li Jing, Li Xueyong ^*; A modified culture strategy of human keratinocytes to shorten the primary culture time, Cell Biology International, 2015, 39 (9):1073-1079.