| Paper Name |
Hybrid biointerface engineering nanoplatform for dual-targeted tumor hypoxia relief and enhanced photodynamic therapy |
| Author |
Xueyan Zhen, Lanlan Jia, Qingyu Tang, Ying Zhao, Peishan Li, Jing Li, Xiaoyu Xie*, Sicen Wang* |
| Publication/Completion Time |
2023-07-02 |
| Magazine Name |
JOURNAL OF COLLOID AND INTERFACE SCIENCE |
| Vol |
647 |
| Related articles |
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| Paper description |
The clinical application of photodynamic therapy (PDT) is limited by the lack of tumor selectivity of photo-sensitizer (PS) and the hypoxic tumor microenvironment (TME). To address these limitations of PDT, we developed a hybrid engineered biointerface nanoplatform that integrated anti-epidermal growth factor receptor (EGFR)-aptamer (EApt)-modified liposomes with tumor cell membranes (TMs) to create M/L-EApt. M/L-EApt exhibited enhanced stability and significant dual-targeting ability, enabling selectively accumulate in hypoxic |
(创新港)
