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论文期刊

论文标题    Astrocyte and ions metabolism during epileptogenesis: A review for modeling studies
作者    Meng-Meng Du(独盟盟), Jia-Jia Li(李佳佳), Zhi-Xuan Yuan(袁治轩), Yong-Chen Fan(范永晨), Ying
发表/完成日期    2020-01-09
期刊名称    Chin. Phys. B
期卷   
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论文简介    As a large group of cells in a central nervous system, astrocytes have a great influence on ion and energy metabolism in a nervous system. Disorders of neuronal ion and energy metabolism caused by impaired astrocytes play a key role in the pathogenesis of epilepsy. This paper reviews the existing computational models of epileptogenesis resulting from im- paired astrocytes and presents several open perspectives with regard to ion and energy metabolism-induced epileptogenesis in a neuron-astrocyte-capillary coupled model.
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