张剑峰
- 研究员
- 博士生导师
- 硕士生导师
- 教师英文名称：Jianfeng Zhang
- 电子邮箱：
- 所在单位：基础医学院
- 学历：博士研究生毕业
- 办公地点：西安交通大学创新港校区和雁塔校区
- 性别：男
- 联系方式：
- 学位：博士学位
- 毕业院校：上海交通大学
- 学科：微生物学,病原生物学
- 学科：微生物学
病原生物学
SecReT6 update: a comprehensive resource of bacterial Type VI Secretion Systems
- 发布时间：2023-03-04
- DOI码：10.1007/s11427-022-2172-x
- 论文名称：SecReT6 update: a comprehensive resource of bacterial Type VI Secretion Systems
- 发表刊物：Science China Life Sciences
- 摘要：Type VI Secretion System (T6SS) plays significant roles in microbial activities via injecting effectors into adjacent cells or environments. T6SS increasingly gained attention due to its important influence on pathogenesis, microbial competition, etc. T6SS-associated research is explosively expanding on numerous grounds that call for an efficient resource. The SecReT6 version 3 provides comprehensive information on T6SS and the interactions between T6SS and T6SS-related proteins such as T6SS regulators and T6SS effectors. To assist T6SS researches like microbial competition and regulatory mechanisms, SecReT6 v3 developed online tools for detection and analysis of T6SS and T6SS-related proteins and estimation of T6SS-dependent killing risk. We have identified a novel T6SS regulator and T6SS-dependent killing capacity in Acinetobacter baumannii clinical isolates with the aid of SecReT6 v3. 17,212 T6SSs and plentiful T6SS-related proteins in 26,573 bacterial complete genomes were also detected, analyzed and incorporated into the database. The database is freely available at https://bioinfo-mml.sjtu.edu.cn/SecReT6/.
- 是否译文：否