Education 2005-2009 Bachelor's degree in Materials Science and Engineering, Harbin Institute of Technology (Harbin, P. R. China) 2009-2013 PhD degree in Biomaterials, National University of Singapore, Singapore 2013-2015 Postdoc in fluorescence molecules for imaging and therapy, IMRE, Astar, Singapore 2015-2020, Associate Professor at School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China 2020-2021, Visiting Professor at Prof Tang Ben Zhong Group at Hong Kong University of Science and Technology, Hong Kong, China 2022- now, Professor at School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China Personal Profile

Prof. Guorui Jin is a Professor and Ph.D. supervisor at the School of Life Science and Technology, Xi’an Jiaotong University. His primary research focuses on biomedical photo-functional materials.

Facing the challenges of aging populations and the rising prevalence of chronic diseases such as cancer, cardiovascular disease, and gastrointestinal disorders, Prof. Jin is dedicated to overcoming the limitations of traditional diagnostic and therapeutic methods. His research emphasizes the development of second near-infrared (NIR-II) bio-photonic functional materials, providing deep tissue penetration and high signal-to-noise ratio imaging.

He has systematically proposed three molecular engineering strategies: enhanced photon absorption, stabilization of long-lived charge separation states, and bidirectional regulation of energy dissipation. These strategies enable deep-tissue imaging and precision therapy, forming a systematic paradigm that provides strong material science support for national health strategies.

His major academic achievements include: serving as principal investigator for one National Key R&D Program on strategic scientific and technological innovation cooperation, two National Natural Science Foundation of China (NSFC) projects (General Program and Young Investigator Fund), and one Shaanxi Provincial Key R&D Project, among a total of seven projects. He has published 62 SCI papers as first or corresponding author in internationally renowned journals such as Chemical Society Reviews, Advanced Materials, Advanced Functional Materials (2), ACS Nano (2), Biomaterials (4), and Theranostics (ESI), including 20 papers with an impact factor greater than 10. He holds two authorized invention patents. He was awarded the Xi’an Youth Science and Technology Talent Award, recognized as one of Xi’an Jiaotong University’s “Top Ten Academic Newcomers,” and received the Shaanxi Provincial First Prize in Natural Science (ranked seventh). He currently serves as Standing Committee Member and Deputy Secretary-General of the Imaging Technology Branch of the Chinese Society for Medical Biotechnology, and Guest Editor for Drug Discovery Today (Elsevier, Q1, IF = 6.5).

Education

2009 – 2013: Ph.D. in Biomedical Engineering, National University of Singapore (Supervisor: Prof. Seeram Ramakrishna)
2005 – 2009: B.S. in Materials Science and Engineering, Harbin Institute of Technology (Supervisor: Prof. Jicai Feng)

Professional Experience

2021 – Present: Professor, School of Life Science and Technology, Xi’an Jiaotong University
2020 – 2021: Visiting Scholar, Department of Chemistry, Hong Kong University of Science and Technology
2015 – 2020: Associate Professor, School of Life Science and Technology, Xi’an Jiaotong University
2013 – 2015: Postdoctoral Fellow & Researcher, Institute of Materials Research and Engineering, A*STAR, Singapore

Academic Service

- Standing Member & Deputy Secretary-General, Imaging Technology Branch, Chinese Society for Medical Biotechnology (2023–Present)
- Standing Member, Biomechanics Committee, Shaanxi Society of Biomedical Engineering (2024–Present)
- Member, Translational Medicine Committee, Shaanxi Anti-Cancer Association (2019–Present)
- Guest Editor, Drug Discovery Today (Elsevier, IF 6.5, Q1) (2016–Present)

Honors and Awards

- 2024: Excellent Paper Award, Nanomedicine Branch, China Integrative Oncology Conference
- 2020: Xi’an Youth Talent Award
- 2016: 1st Place, Young Investigator Oral Award, TERMIS-AP (Taiwan)
- 2015: Best Poster Award, 5th Molecular and Materials Meeting, Singapore
- 2012: Excellent Paper Award, Japanese Society for Bioscience and Technology

Research Grants (PI)

- 2024–2028: Development of exosome-mimetic nanovesicle fabrication and surface modification via microfluidics, Shaanxi Provincial Key R&D Program (¥700,000)
- 2020–2024: Mechanistic study of stiffness-gradient tunable graphene hydrogels on neural regeneration, National Key R&D Program (¥1.2M)
- 2020–2023: Temperature-responsive AIE nanoprobes for tumor diagnosis and therapy, NSFC General Project (¥570,000)
- 2017–2019: NSFC Young Investigator Fund (¥200,000)
- 2015–2017: Research Fund for Returned Overseas Scholars (¥150,000)

Selected Publications

Prof. Jin has published 62 SCI papers as first or corresponding author in top journals including Chem. Soc. Rev., Advanced Materials, Advanced Functional Materials, ACS Nano, Biomaterials, and Theranostics. Over 20 papers have an IF > 10. 

2025

62 Wenjing Liu, Huilin Xie, Jianlin Liu, Na Zhu, Suyin Wang, Rongfeng Wang, Xiaogang Zhang, Guangkui Xu, Guy M. Genin, Feng Xu,* Jianquan Zhang,* Guorui Jin (通讯),* and Ben Zhong Tang*, Molecularly Locked π-Bridge Endows AIEgen with 1064 nm Excitation for Deep Tissue Imaging, Adv. Funct. Mater. 2025, 2501668 (材料科学领域的顶级期刊IF 18.173)

61 Wenjing Liu, Zhongyan Hu,* Jianyu Zhang, Jing Zhao, Suyin Wang, Xianxiu Xu, Guangkui Xu, Guy M. Genin, Yixuan Shao, Lianrui Hu,* Feng Xu,* Guorui Jin (通讯),* and Ben Zhong Tang*, Tailoring Long-Lived Charge Separation Enables Efficient Light-to-Heat Conversion for Efficient Cancer Therapy, ACS Nano 2025, 19, 29503−29516 (纳米科学领域顶刊 IF 15.8)

60. Yan Feng, Junjun Ni, Huilin Xie, Na Zhu, Wenjing Liu, Liang Guo, Jianquan Zhang, Jia Di, Shuixiang He, Hao Hu, Hui Xing, Feng Xu, Guorui Jin（通讯）*, Ben Zhong Tang*, Xiaoran Yin*, NIR-II AIEgen with High Photothermal Efficiency for Mild PTT: Optimized Natural Killer  Cell Spatial Distribution for Boosted Immune Response,  Biomaterials, 2025, 321 (2025) 123340 (生物材料顶刊 IF 12.6)

59. Jianlin Liu, Wenjing Liu, Guanghui Liu, Rongfeng Wang, Jing Liu, Xiaogang Zhang, Heping Shi, Xiuqing Dong, Jing Zhao*, Dan Ding*, Guorui Jin （末位通讯）*, NIR-II AIEgen nanocomplex with suppressed nonradiative decay and intersystem crossing for high-contrast mesenteric vascular imaging, Biomaterials, 2025, 319, 123229 (生物材料顶刊 IF 12.6)

58. Zhongyan Hu, Wenjing Liu, Jianyu Zhang, Xiaoyu Guo, Huaquan Fang, Junjun Ni, Jacky W.Y. Lam, Ryan T.K. Kwok, Feng Xu, Guorui Jin（通讯）*, Ben Zhong Tang*, Engineering long-lived charge separation states boosts type-I ROS generation for efficient cancer therapy, Biomaterials, 2025, 319, 123218 (生物材料顶刊 IF 12.6)

57. Jing Zhang, Xiao-Wen Han, Pu Chen, Guo-Gang Shan, Guorui Jin, Hai-Tao Feng, and Ben Zhong Tang, Photodynamic Therapy-Accelerated HypoxiaResponsive Prodrug Release for Synergistic Photo-Chemotherapy of Melanoma Cancer Based on Noncovalent Interactions, ACS Materials Lett. 2025, 7, 770−779 (IF 11.17)

56. Yunfei Zuo, Pei Li, Wen-Jin Wang, Changhuo Xu, Shuting Xu, Herman H. Y. Sung, Jianwei Sun, Guorui Jin, Weiping Wang, Ryan T. K. Kwok,* Jacky W. Y. Lam,*and Ben Zhong Tang, Tumor Site-Specific In Vivo Theranostics Enabled by Microenvironment-Dependent Chemical Transformation and Self-Amplifying Effect, Adv. Sci. 2025, 12, 2409506 (综合类TOP期刊 IF 15.1)

2024

55. Mingwang Yang, Suyin Wang, Xinwen Ou, Junjun Ni, Shinsuke Segawa, Jianwei Sun, Feng Xu, Ryan T. K. Kwok, Jing Zhao,* Jacky W. Y. Lam,* Guorui Jin（通讯）,* and Ben Zhong Tang*, Reengineering of Donor−Acceptor−Donor Structured Near-Infrared II Aggregation Induced Emission Luminogens for Starving Photothermal Antitumor and Inhibition of Lung Metastasis, ACS Nano 2024, 18, 30069−30083 (纳米科学领域顶刊 IF 15.8) 

54. Shanshan Zhu, Huan Gao, Wenyuan Li, Xiaocong He, Panpan Jiang, Feng Xu, Guorui Jin（通讯）,* and Hui Guo,* Stimuli-Responsive Aptamer-Drug Conjugates for Targeted Drug Delivery and Controlled Drug Release, Adv. Healthcare Mater. 2024, 13, 2401020 （IF 10）

2023

53. 倪钧钧，郭亮，王素音，朱娜，赵婧，靳国瑞（末位通讯），生物医用一氧化氮控释光学功能材料及其在皮肤再生中的应用研究，《中国医药生物技术》2023, 18(6)

52. Wenfang Li, Huan Gao, Suyin Wang, Yangjing Liu, Junjun Ni, Fengxue Xin, Jin Yang, Xiaogang Guo, Guoxu Zhao*, Guorui Jin（通讯）*, and Jing Zhao*, Dual Gene-Loaded Near-Infrared AIEgen Nanoplatforms with Promoted Proliferation, Relieved Immunosuppression, and Tracking Capabilities for Cardiomyocyte Transplantation, ACS Appl. Nano Mater. 2023, 6, 18, 16536–16545

51.Jing Zhang#, Wenjing Liu#, Yangjing Liu#, Jianyu Zhang, Pengfei Gao, Lei Zheng*, Feng Xu*, Guorui Jin（通讯）*, Ben Zhong Tang*, A New Strategy to Elevate Absorptivity of AIEgens for Intensified Nir-Ii Emission And Synergized Multimodality Therapy, Advanced Materials, 2023, 2306616（材料科学顶刊 IF 27.4）

2022

50. Guoxu Zhao, Hongwei Zhou, Guorui Jin, Birui Jin, Songmei Geng, Zhengtang Luo, Zigang Ge, Feng Xu, Rational design of electrically conductive biomaterials toward excitable tissues regeneration, Progress in Polymer Science, 2022, 101573

49. Yuting Cai, Qun Huang, Penghui Wang, Kaichuang Ye, Zhen Zhao, Haomin Chen, Zhenjing Liu, Hongwei Liu, Hoilun Wong, Mohsen Tamtaji, Kenan Zhang, Feng Xu, Guorui Jin, Lun Zeng, Jianbo Xie, Yucong Du, Zhigang Hu, Dazhi Sun, Jinbao Qin, Xinwu Lu, Zhengtang Luo, Conductive Hydrogel Conduits with Growth Factor Gradients for Peripheral Nerve Repair in Diabetics with Non-Suture Tape, Adv. Healthcare Mater. 2022, 11, 2200755.