(4.)Research Experience

Research Focus Areas

Dr. Qian’s research mainly focuses on the pathogenesis, prevention and treatment of neurodegenerative diseases. To elucidate the mechanism of production, deposition and degradation of amyloid protein in AD models, and to explore the prevention and treatment mechanism of traditional Chinese medicine and small molecular substances on AD model animals.

Dr. Qian has been Hosted three National Natural Science Foundation of China, one provincial key project and a number of provincial and municipal scientific research projects. She won the second prize of Science and Technology Progress of Shaanxi Province in 2004, and published more than 100 research papers, including 43 SCI.

Research Projects.

Research Projects

1. The regulatory effects of p38MAPK signaling pathway on LRP and α7nACh receptor-mediated internalization of amyloid beta protein.  This project was supported by the Natural Science Foundation of China (No. 81071035).

2. The regulation of JNK/ERK1/2 signal transduction pathway on the receptor-mediated internalization of beta amyloid protein and its mechanism. This project was supported by the Natural Science Foundation of China ( No. 81571251).

3.Research on physical anthropology of Han nationality. This project was supported by the Natural Science Foundation of China (No.30830062).

4. The regulatory mechanism of Tβ4 on relieving neuroinflammation induced by beta amyloid protein  target NF-κB signaling molecule, Basic Research Plan of Natural Science in Shaanxi Province-key projects（2019JZ-21）

5. The study of the relation of Alzheimer's disease and polymorphism of p35 gene on Han nationality of China. This project was supported by the Grant from Shaanxi Province (2005K13-G2)

6. The mechanism of the dipsacus asper inhibiting the deposition of amyloid protein in dementia

model rats.

7.Experimental study on the mechanism of the total saponin of dipsacus asper in the cellular

model of Alzheimer’s disease.

8. Experimental study on the treatment and preventing of tanshinones in model of Alzheimer’s

disease.