长期致力于生物传感器的研发工作，主要研究方向为生物医学传感分析、药物作用过程分析及药品分析与评价，包括纳米生物技术、功能生物传感、活体分析、芯片分析、免疫、细胞和基因分析及临床检验技术等。

[1] Fuyun Xia, Jiatao Chen, Pengbo Yang, Meilin Shi, Buyi Wang, Dongdong Zhang*. A biocompatible microsensor based on a cation-selective nanoporous conductive hydrogel for stable electrochemical sensing of dopamine in mouse brain. ACS Sens., 2026, 11, 2241-2251.

[2]  Jiatao Chen, Fuyun Xia, Xinxin Zhao, Buyi Wang, Meilin Shi, Dongdong Zhang*. Covalent immobilization of hydrogels on carbon fiber microelectrodes for the determination of dopamine in the living mouse brain. ACS Appl. Bio Mater., 2026, 9, 4267-4277.

[3]  Jiatao Chen, Fuyun Xia, Xiuting Ding, Dongdong Zhang*. Highly sensitive and biocompatible microsensor for selective dynamic monitoring of dopamine in rat brain. ACS Sens., 2024, 9, 6207-6217.

[4] Jiatao Chen, Fuyun Xia, Xiuting Ding, Dongdong Zhang*. Universal covalent grafting strategy of an aptamer on a carbon fiber microelectrode for selective determination of dopamine in vivo. Anal. Chem., 2024, 96, 10322-10331.

[5]  Jiatao Chen, Dandan Li, Xiuting Ding, Dongdong Zhang*. Sensitive and selective electrochemical aptasensing method for the voltammetric determination of dopamine based on AuNPs/PEDOT-ERGO nanocomposites. Bioelectrochemistry., 2024, 157, 108653.

[6]  Jiatao Chen, Xiuting Ding, Dongdong Zhang*. Challenges and strategies faced in the electrochemical biosensing analysis of neurochemicals in vivo: A review. Talanta., 2024, 266, 124933.

[7]  Jiatao Chen, Xian Ran, Xiuting Ding, Dongdong Zhang*. Dual electrochemical quantitative analysis of dopamine based on flow injection amperometry with double glassy carbon electrodes. Electrochem. Commun., 2023, 51, 107511.

[8]  Dongdong Zhang, Yanmin Zhang, Lei Zheng, Yingzhuan Zhan, Langchong He*. Graphene oxide/poly-L-lysine assembled layer for adhesion and electrochemical impedance detectiono fleukemia K562 cancer cells. Biosens. Bioelectron., 2013, 42, 112-118.

[9]  Dongdong Zhang*, Lei Fu, Lei Liao, Nan Liu, Boya Dai, Chengxiao Zhang*. Preparation, characterization, and application of electrochemically functional graphene nanocomposites by one-Step liquid-phase exfoliation of natural flake graphite with methylene blue. Nano Res., 2012, 5(12), 875-887.

[10]  Dongdong Zhang, Lei Fu*, Lei Liao, Boya Dai, Rui Zou, Chengxiao Zhang*. Electrochemically functional graphene nanostructure and layer-by-layer nanocomposite incorporating adsorption of electroactive methylene blue. Electrochim. Acta, 2012, 75, 71-79.

[11]  Dongdong Zhang, Yage Peng, Honglan Qi, Qiang Gao, Chengxiao Zhang*. Label-free electrochemical DNA biosensor array for simultaneous detection of the HIV-1 and HIV-2 oligonucleotides incorporating different hairpin-DNA probes and Redox Indicator. Biosens. Bioelectron., 2010, 25, 1088-1094.

[12]  Dongdong Zhang, Yage Peng, Honglan Qi, Qiang Gao, Chengxiao Zhang*. Application of multielectrode array modified with carbon nanotubes to simultaneous amperometric determination of dihydroxy- benzene isomers. Sens. Actuators B, 2008, 136(1), 113-121.