Personal Information

             

Prof. Fanglin Guan, PhD

Institute of Neuroscience, Bio-evidence Sciences Academy

Xi’an Jiaotong University Health Science Center

Contact Information

Address76 Yanta West RoadXi’anShaanxi

 

Zip code:710061

 

Emailfanglingguan@163.com

Representative Publications(since 2020)

1.Zhu L, Ni T, Guan F#. Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention. Am J Psychiatry. 2024 Feb 1;181(2):168.

 

2.Jiang Z*, Zhang T*, Han W, Xiao J, Zhang W, Wang X, Liu J, Yang Y, Yang C, Guan F#, Li T#, Rice JP. Identification of PROK2 gene polymorphisms as predictors of methamphetamine use disorder risk and indicators of craving scale in the Chinese Han population. Front Pharmacol. 2023 Jul 6;14:1217382.

 

3.Cui LB*, Wang XY*, Fu YF*, Liu XF*, Wei Y, Zhao SW, Gu YW, Fan JW, Wu WJ, Gong H, Lin BD, Yin H, Guan F#, Chang X#. Transcriptional level of inflammation markers associates with short-term brain structural changes in first-episode schizophrenia. BMC Med. 2023 Jul 10;21(1):250.  

 

4.Wang H*, Ma Y*, Wang X*, Zhang W, Han W, Liu H, Li M, Xiao J, Wei H, Wang C, Sindhwani S, Zhang T#, Guan F#, Rice JP. Evaluation of Adenosine A2A receptor gene polymorphisms as risk factors of methamphetamine use disorder susceptibility and predictors of craving degree. Psychiatry Res. 2022 Oct;316:114790.

 

5.Ni T*, Zhu L, Wang S, Su L, Li M, Zhu W, Xue Y, Zhu Y, Wang H, Guan F#, Chen T#. Medial prefrontal cortex Notch signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABAB1 receptor expression. Molecular Psychiatry, 2022 Oct;27(10):4009-4022.  

 

6.Zhu L*, Zhu Y, Wu F, He L, Wang S, Hu H, Eyleen L.K. Goh, Guan F#, Chen T#. A novel microRNA, novel-m009C, controls methamphetamine reward by targeting Grin1. Molecular Psychiatry, 2022 Sep;27(9):3885-3897. 

 

7.Xiao J*, Ma Y*, Wang X*, Wang C, Li M, Liu H, Han W, Wang H, Zhang W, Wei H, Zhao L, Zhang T#, Lin H#, Guan F#. The Vulnerability to Methamphetamine Dependence and Genetics: A Case-Control Study Focusing on Genetic Polymorphisms at Chromosomal Region 5q31.3. Front Psychiatry. 2022 May 20;13:870322.

 

8.Shen C*, Li H*, Li M*, Niu Y*, Liu J, Zhu L, Gui H, Han W, Wang H, Zhang W, Wang X, Luo X#, Sun Y#, Yan J#, Guan F#. DLRAPom: a hybrid pipeline of Optimized XGBoost-guided integrative multiomics analysis for identifying targetable disease-related lncRNA-miRNA-mRNA regulatory axes. Brief Bioinform. 2022 Feb 28:bbac046. 

 

9.Wang Y*, Zhang J*, Deji C, Fan J, Miao X, Li S, Zeng X#, Guan F#. Differential perturbations of gut microbial profiles and co-occurrence networks among phases of methamphetamine-induced conditioned place preference. J Neurosci Res. 2021 Nov;99(11):2860-2873.

 

10.Guan F*, Ni T*, Zhu W*, Williams LK, Cui LB, Li M, Tubbs J, Sham PC#, Gui H#. Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction. Mol Psychiatry. 2022 Jan;27(1):113-126.  

 

11.Guo S*, Liu J*#, Li W*, Yang Y, Lv L, Xiao X, Li M, Guan F#, Luo XJ#. Genome wide association study identifies four loci for early onset schizophrenia. Transl Psychaitry. 2021 Apr 27;11(1):248. 

 

12.Qi X*, Guan F*, Cheng S, Wen Y, Liu L, Ma M, Cheng B, Liang C, Zhang L, Liang X, Li P, Chu X, Ye J, Yao Y, Zhang F#. Sex specific effect of gut microbiota on the risk of psychiatric disorders: A Mendelian randomisation study and PRS analysis using UK Biobank cohort. Word J Biol Psychaitry. 2021 Sep;22(7):495-504.

 

13.Cheng S*, Guan F*, Ma M, Zhang L, Cheng B, Qi X, Liang C, Li P, Kafle OP, Wen Y, Zhang F#. An atlas of genetic correlations between psychiatric disorders and human blood plasma proteome. Eur Psychaitry. 2020 Feb 20;63(1):e17. 

 

14.Zhu Y*, Zou C*, Zhang J*, Jiang W,* Guan F*, Tang K, Li S, Li G, Wang J, Ke Z#. Dynamically Monitoring the Clonal Evolution of Lung Cancer Based on the Molecular Characterization of Circulating Tumor Cells Using Aptamer Cocktail-Modified Nanosubstrates. ACS Appl Mater Interfaces. 2020 Feb 5;12(5):5671-5679.

 

15.Guan F*, Ni T*, Han W, Lin H, Zhang B, Chen G, Zhu L, Liu D, Zhang T#. Evaluation of the relationships of the WBP1L gene with schizophrenia and the general psychopathology scale based on a case-control study. Am J Med Genet B Neuropsychiatr Genet. 2020 Apr; 183(3):164-171.

 

16.Guan F*, Zhang T*, Han W, Zhu L, Ni T, Lin H, Liu D, Chen G, Xiao J, Li T#. Relationship of SNAP25 variants with schizophrenia and antipsychotic-induced weight change in large-scale schizophrenia patients. Schizophr Res. 2020 Jan;215:250-255.

 

17.Qi X*, Guan F*, Wen Y, Li P, Ma M, Cheng S, Zhang L, Liang C, Cheng B, Zhang F#. Integrating genome-wide association study and methylation functional annotation data identified candidate genes and pathways for schizophrenia. Prog Neuropsychopharmacol Biol Psychaitry. 2020 Jan 10; 96:109736.