徐华栋 Ph.D.
副教授
线粒体生物医学研究所
生命科学与技术学院
生物医学与健康工程研究院
Home - 徐 华栋
西安交通大学
生命科学与技术学院
联系电话：029-82668463-409
E-mail: hdxu2022@xjtu.edu.cn
hdxu@pku.edu.cn
通讯地址：陕西省西安市碑林区咸宁西路28号西安交通大学生命科学与技术学院, 西安，710049
2009年获中央民族大学生物科学学士学位、2015年获北京大学生理学博士学位；2015-2018年在北京大学校企未名集团担任高级研究员；2019-2022年在西南医科大学心血管医学研究所任副研究员；2022年加入西安交通大学生命科学与技术学院。2019年至今，担任中国生物物理学会神经生物物理分会副秘书长兼委员。学术研究领域为神经分泌与脑疾病机制，利用电生理、电化学、光遗传学、化学遗传学、在体成像等特色优势技术，研究帕金森疾病的运动障碍、情绪障碍的病理机制，以及抑郁、焦虑等情绪障碍的神经环路机制。目前主持国家/省部级项目4项，包括国家自然青年科学基金1项和四川省科技厅应用基础项目1项、陕西省科技厅基础研究面上项目1项、陕西省博士后特别资助项目1项。在Nature neurosci、Brain、PNAS、Nature comun等国际学术期刊上发表文章十余篇。
2009.9–2015.1, 北京大学, 生理学, 博士, 导师: 周专
2005.9–2009.7, 中央民族大学, 生物科学, 学士, 导师: 覃晓燕
(1)Qian Song#, Anqi Wei#, Huadong Xu#, Yuhao Gu#, Yong Jiang, Nan Dong, Chaowen Zheng, Qinglong Wang, Min Gao, Suhua Sun, Xueting Duan, Yang Chen, Bianbian Wang, Jingxiao Huo, Jingyu Yao, Hao Wu, Hua Li, Xuanang Wu, Zexin Jing, Xiaoying Liu, Yuxin Yang, Shaoqin Hu, Anran Zhao, Hongyan Wang, Xu Cheng, Yuhao Qin, Qiumin Qu, Tao Chen, Zhuan Zhou, Zuying Chai*, Xinjiang Kang*, Feng Wei*, and Changhe Wang*. An ACC-VTA-ACC positive-feedback loop mediates the persistence of neuropathic pain and emotional consequences. Nat Neurosci, 2024
(2) Xu Huadong#, cheng Xu#, Song qian, Wang Changhe, Kang Xingjiang, Induced dopaminergic neurons for Parkinson’s disease therapy: targeting striatum or midbrain/substantia nigra par compacta?
Neuroscience Bulletin, 2022 (期刊论文)
(3) Jiao Ruiying, Liu Wei, Yin Lili, Qiao Zhongjun, Li Jie, Zhou Li, Muhammad Younus, Wang Li, Xu Huadong*, Zhou Zhuan *, A method for recording the two phases of dopamine release in mammalian brain striatum slices, Analyst, 2020,145, 453-459 (期刊论文)
(4) Li, Mingli#; Xu, Huadong#; Chen, Guoqing; Sun, Suhua; Wang, Qinglong; Liu, Bing; Wu, Xi; Zhou, Li; Chai, Zuying; Sun, Xiaoxuan; Lu, Yang; Younus, Muhammad; Zheng, Lianghong; Zhu, Feipeng; Jia, Hongbo; Chen, Xiaowei; Wang, Changhe; Zhou, Zhuan*, Impaired D2 receptor-dependent dopaminergic transmission in prefrontal cortex of awake mouse model of Parkinson's disease, Brain, 2019,142(10):3099–3115 (期刊论文)
(5) Xu Huadong#; Zuo Panli#; Wang Shirong#; Zhou Li; Sun Xiaoxuan; HuMeiqin; Liu Bin; Wu Qihui; Dou Haiqiang; Liu Bing; Zhu Feipeng; Teng Sasa; Zhang Xiaoyu; Wang Li; Li Qing; Jin Mu; Kang Xinjiang ; Xiong Wei; Wang Changhe ; Zhou Zhuan , Striatal dopamine release in a schizophrenia mouse model measured by electrochemical amperometry in vivo , Analyst, 2015, 140(11): 3840~3845 (期刊论文)
(6) Kang Xinjiang#; Xu Huadong#; Teng Sasa#; Zhang Xiaoyu; Deng Zijun; Zhou Li; Zuo Panli; Liu Bing; Liu Bin; Wu Qihui; Wang Li; Hu Meiqin; Dou Haiqiang; Liu Wei; Zhu Feipeng; Li Qing; Guo Shu; Gu Jingli; Lei Qian; Lu Jing; Mu Yu; Jin Mu; Wang Shirong; Jiang Wei; Liu Kun; Wang Changhe; Li Wenlin; Zhang Kang; Zhou Zhuan* ,Dopamine release from transplanted neural stem cells in Parkinsonian rat striatum in vivo , Proceedings of the National Academy of Sciences of the United States of America, 2014.11.4, 111(44): 15804~15809(期刊论文)
（7）Changhe Wang#, Xinjiang Kang#, Li Zhou#, Zuying Chai,Qihui Wu, Rong Huang,Huadong Xu , Meiqin Hu, Xiaoxuan Sun, Suhua Sun,Jie Li , Ruiying Jiao, Panli Zuo, Lianghong Zheng, Zhenyu Yue, Zhuan Zhou*,Synaptotagmin-11 is a critical mediator of parkin linked neurotoxicity and Parkinson’s Disease-like pathology.Nat. Commun. 2018 Jan 8;9(1):81
(8)Wang L#, Zhang XY#, Xu HD, Zhou L, Jiao RY, Liu W, Zhu FP, Kang XJ, Liu B, Teng SS, Wu QH, Li ML, Dou HQ, Wang CH, Zuo PL, Wang SR and Zhou Z*, Temporal components of synapse-synapse transmission in dorsal striatum brain slices of mice. Journal of Physiology, 2014 592:3559–3576.
