液相色谱的分离性能与孔隙结构密切相关，微加工技术为控制微观孔隙结构提供了可能。因此采用微加工技术制备的微型液相色谱柱相比于传统的颗粒填充色谱柱具有更大的优势。本实验室在液相色谱动力学理论，高效色谱柱结构设计方面开展研究，取得了一些成果。
新型色谱柱结构
胶体晶体内传质动力学理论
颗粒填充色谱柱内传质动力学
相关论文：
（1）Tian XY, Deng XZ, Tan XJ, Yan XH*, Numerical evaluation of the diffusion enhancement in meso-microporous materials originating from mesopores,Microporous and Mesoporous Materials, 2017,245:58-63.
（2）Yan XH*, Li N, Simulation of solute dispersion in particle packs by the volume averaging method,Computers & Chemical Engineering, 2017,98:154-160.
（3）Yan XH*,Li L, Wang QW, An empirical correlation of the longitudinal and transverse dispersion coefficients for flow through random particle packs, Chemical Engineering Science, 2015. (SCI,通讯作者)
（4）Yan XH*, Wang QW, Li N, Predictive model of solute transport with reversible adsorption in hierarchical porous media, Journal of Chromatography A，2015.(SCI,通讯作者)
（5）张照明，王苗，闫孝红*，颗粒填充柱内溶质弥散系数的体积平均方法研究，《化学工程》，2015，3：25-28。
（6）闫孝红*，谭小江，王秋旺，双级孔材料内组分有效扩散系数的理论计算，《化学工程》，2015接收。
（7）Yan XH*, Li N, Nanopillar array with multiscale inter-pillar spacing as chromatography stationary phase support: theoretical performance evaluation, Chemical Engineering Science, 2014. (SCI, 通讯作者)
（8）Yan XH*, Wang QW, Comparative analysis of chromatography dynamic models in predicting the plate height contributed by interphase mass transfer, Chemical Engineering Science, 2013, 104: 760-766. (SCI，通讯作者)
（9）Yan XH*, Wang QW, Numerical investigation into the effects of ordered particle packing and slip flow on the performance of chromatography, Journal of Separation Science, 2013, 36: 1524-1529. (SCI，通讯作者)
（10）Yan XH, Wang QW, Bau HH*, Dispersion in retentive pillar array columns, Journal of Chromatography A, 2010, 1217: 1332-1342. (SCI)
