Basic Information

 

Yi Zhang PhD

Associate Professor

 

Department of Physiology and Pathphysiology

School of Basic Medical Sciences

Xi'an Jiaotong University Health Science Center

 

 

Visiting

Publications

  1. Yu Zhang#, Jing-Jing Li#, Rui Xu, Xin-Pei Wang, Xin-Yi Zhao, Yuan Fang, Yu-Peng Chen, Shan Ma, Xiao-Hui Di, Wei Wu, Gang She, Zheng-Da Pang, Yi-Dong Wang, Xing Zhang, Wenjun Xie, Xiu-Ling Deng, Xiao-Jun Du, Yi Zhang*(corresponding author). Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts. Redox Biol. 2023 Oct; 68:102944. (IF=11.4)
  2. Jing-Jing Li#, Xin-Yi Zhao#, Yan Wang#, Rui Xu, Xiao-Hui Di, Yu Zhang, Hongyan Yang, Meng-Zhuan Han, Ru-Yue Bai, Lin Xie, Zheng-Da Pang, Xing Zhang, Jianbao Zhang, Xiao-Jun Du, Xiu-Ling Deng*, Yi Zhang*(corresponding author), Wenjun Xie*. Endothelial KCa3.1 and KCa2.3 Mediate S1P (Sphingosine-1-Phosphate)-Dependent Vasodilation and Blood Pressure Homeostasis. Arterioscler Thromb Vasc Biol. 2023 May; 43(5):726-738. (IF=10.514)
  3. Yi Zhang#, Xiao-Zhen Ma#, Xin-Yi Zhao, Jing-Jing Li, Shan Ma, Zheng-Da Pang, Jing Xu, Xiao-Jun Du, Xiu-Ling Deng*, Jun-Hong Wang*. AGEs-RAGE-KCa3.1 pathway mediates palmitic acid-induced migration of PBMCs from patients with type 2 diabetes. Heliyon. 2023 Mar 24;9(4):e14823. (IF=4.0)
  4. Linda Sasset#, Onorina Laura Manzo#, Yi Zhang# (co-first author), Alice Marino, Luisa Rubinelli, Maria Antonietta Riemma, Madhavi Latha S Chalasani, Dragos C Dasoveanu, Fiorentina Roviezzo, Stanislovas S Jankauskas, Gaetano Santulli, Maria Rosaria Bucci, Theresa T Lu, Annarita Di Lonrenzo*. Nogo-A reduces ceramide de novo biosynthesis to protect from heart failure. Cardiovasc Res. 2023 Mar 31;119(2):506-519. (IF=14.239)
  5. Zheng-Da Pang#, Xia Sun#, Ru-Yue Bai, Meng-Zhuan Han, Yong-Jian Zhang, Wei Wu, Yu Zhang, Bao-Chang Lai, Yi Zhang, Yan Wang, Xiao-Jun Du, Xiu-Ling Deng*. YAP-galectin-3 signaling mediates endothelial dysfunction in angiotensin II-induced hypertension in mice. Cell Mol Life Sci. 2023 Jan 11;80(2):38. (IF=9.207)
  6. Gang She, Jin-Chan Du, Wei Wu, Tian-Tian Pu, Yu Zhang, Ru-Yue Bai, Yi Zhang, Zheng-Da Pang, Hui-Fang Wang, Yu-Jie Ren, Junichi Sadoshima, Xiu-Ling Deng, Xiao-Jun Du*. Hippo pathway activation mediates chemotherapy-induced anti-cancer effect and cardiomyopathy through causing mitochondrial damage and dysfunction. Theranostics. 2023 Jan 1;13(2):560-577. (IF=11.600)
  7. 戚瑛, 赵芯仪, 姚佳辉, 谢文俊, 张伊*. IP3R和RyR对新生大鼠心肌细胞钙振荡的调控研究. 西安交通大学学报(医学版).Ying Qi, Xinyi Zhao, Jiahui Yao, Wenjun Xie, Yi Zhang*(corresponding author). Regulation of calcium oscillations by IP3R and RyR in neonatal rat cardiomyocytes.  J Xi’an Jiaotong Univ Med Sci. 2022; 43(6):801-806.
  8. Wei Wu, Mark Ziemann, Kevin Huynh, Gang She, Zheng-Da Pang, Yi Zhang, Thy Duong, Helen Kiriazis, Tian-Tian Pu, Ru-Yue Bai, Jing-Jing Li, Yu Zhang, Ming-Xia Chen, Junichi Sadoshima, Xiu-Ling Deng, Peter J Meikle, Xiao-Jun Du*. Activation of Hippo signaling pathway mediates mitochondria dysfunction and dilated cardiomyopathy in mice. Theranostics. 2021 Aug 21; 11(18):8993-9008. (IF=11.600)
  9. Zheng-Da Pang, Yang Wang, Zheng Song, Gang She, Xiao-Zhen Ma, Xia Sun Wei Wu, Bao-Chang Lai, Jiao Zhang, Yi Zhang, Xiao-Jun Du, John Y J Shyy*, Xiu-Ling Deng*. AMPK upregulates KCa2.3 channels and ameliorates endothelial dysfunction in diet-induced obese mice. Biochem Pharmacol. 2021 Jan; 183:114337. (IF=6.100)
  10. Yi Zhang#, Ying Qi#, Jingjing Li#, Xiaohang Gao, Yu Zhang, Xia Sun, Wenjin He, Jie Tong, Jianbao Zhang, Xiu-Ling Deng, Xiao-Jun Du, Wenjun Xie*. Stretch-induced sarcoplasmic reticulum calcium leak is causitively associated with atrial fibrillation in pressure-overloaded hearts. Cardiovasc Res. 2021 Apr; 117(4):1091-1102. (IF=14.239, ESI highly cited paper)
  11. Ying Qi#, Jing-Jing Li#, Xiao-Hui Di#, Yu Zhang#, Jie-Long Chen, Zi-Xuan Wu, Zi-Yue Man, Ru-Yue Bai, Fujian Lu, Jie Tong, Xue-Liang Liu, Xiu-Ling Deng, Jianbao Zhang, Xing Zhang, Yi Zhang*(corresponding author), and Wenjun Xie*. Excess sarcoplasmic reticulum-mitochondria calcium transport induced by sphingosine-1-phosphate contributes to cardiomyocyte hypertrophy. Biochim Biophys Acta Mol Cell Res. 2021 Apr; 1868(5):118970. (IF:5.011)
  12. Yi Zhang#, Meng-Chen Hou#, Jingjing Li,Ying Qi, Yu Zhang, Gang She,Yu-Jie Ren, Wei Wu, Zheng-Da Pang, Wenjun Xie, Xiu-Ling Deng*, Xiao-Jun Du*. Cardiac β-adrenoceptor activation mediates diverse and cell type-dependent changes in the expression and distribution of connexin 43. J Cell Mol Med. 2020 Aug; 24(15):8505-8517. (IF=5.310)
  13. Gang She, Meng-Chen Hou, Yu Zhang, Yi Zhang, Yan Wang, Hui-Fang Wang, Bao-Chang Lai, Wei-Bo Zhao, Xiao-Jun Du, Xiu-Ling Deng*.Gal-3 (Galectin-3) and KCa3.1 Mediate Heterogeneous Cell Coupling and Myocardial Fibrogenesis Driven by βAR (β-Adrenoceptor) Activation. Hypertension. 2020 Feb;75(2):393-404. (IF=10.190)
  14. Alice Marino, Yi Zhang, Luisa Rubinelli, Maria Antonietta Riemma, James E. Ip, Annarita Di Lorenzo*. Pressure overload leads to coronary plaque formation, progression and myocardial events in ApoE-/- mice. JCI Insight. 2019;4(9):e128220. (IF=6.014)
  15. Gregory Farber, Matthew M. Parks, Nicole Lustgarten Guahmich, Yi Zhang, Sébastien Monette, Scott C. Blanchard, Annarita Di Lorenzo, Carl P. Blobe*, ADAM10 controls the differentiation of the coronary arterial endothelium, Angiogenesis. 2018. doi: 10.1007/s10456-018-9653-2. (IF=5.759)
  16. Ren Xu, Alisha Yallowitz, An Qin, Zhuhao Wu, Dong Yeon Shin, Jung-Min Kim, Shawon Debnath, Gang Ji, Mathias P. Bostrom, Xu Yang, Chao Zhang, Han Dong, Pouneh Kermani, Sarfaraz Lalani, Na Li, Yifang Liu, Michael G. Poulos, Amanda Wach, Yi Zhang, Kazuki Inoue, Annarita Di Lorenzo, Baohong Zhao, Jason M. Butler, Jae-Hyuck Shim, Laurie H. Glimcher*, Matthew B. Greenblatt*, Targeting skeletal endothelium to ameliorate bone loss, Nat Med. 2018, 24(6): 823–833.(IF=30.641)
  17. Swendeman Steven L, Xiong Yuquan, Cantalupo Anna, Yuan Hui, Burg Nathalie, Hisano Yu, Cartier Andreane, Liu Catherine H, Engelbrecht Eric, Blaho Victoria, Yi Zhang, Yanagida Keisuke, Galvani Sylvain, Obinata Hideru, Salmon Jane E, Sanchez Teresa, Di Lorenzo Annarita, Hla Timothy*, An engineered S1P chaperone attenuates hypertension and ischemic injury, Sci Signal. 2017, 10(492):1-30 (IF=6.481)
  18. Anna Cantalupo, Antonella Gargiulo, Elona Dautaj, Catherine Liu, Yi Zhang, Timothy Hla, and Annarita Di Lorenzo, S1PR1 (Sphingosine-1-Phosphate Receptor 1) Signaling Regulates Blood Flow and Pressure. Hypertension. 2017 Jun 12; 70(2): 426~434 (IF=7.017)
  19. Linda Sasset#, Yi Zhang# (co-first author), Teresa M. Dunn, and Annarita Di Lorenzo*. Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis. Trends Endocrinol Metab. 2016 Nov;27(11):807-819. pii:S1043-2760(16)30088-1. (IF=10.983)
  20. Yi Zhang, Yan Huang, Anna Cantalupo, Paula S. Azevedo, Mauro Siragusa, Jacek Bielawski, Frank J. Giordano, and Annarita Di Lorenzo*. Endothelial Nogo-B regulates sphingolipid biosynthesis to promote the transition from hypertrophy to heart failure during chronic pressure overload. JCI Insight. 2016 Apr 21; 1(5): e85484. (IF=6.014)
  21. Anna Cantalupo#, Yi Zhang# (co-first author), Milankumar Kothiya, Sylvain Galvani, Hideru Obinata, Mariarosaria Bucci, Frank J. G。iordano, Xian-Cheng Jiang, Timothy Hla, and Annarita Di Lorenzo*. Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure. Nat Med. 2015 Sep; 21(9):1028-37. (IF=30.641)
  22. Xianhua Wang*#, Wenjun Xie#, Yi Zhang# (co-first author), Peihui Lin, Liang Han, Peidong Han, YanruWang, Zheng Chen, Guangju Ji, Ming Zheng, Noah Weisleder, Rui-Ping Xiao, Hiroshi Takeshima, Jianjie Ma*, and Heping Cheng. Cardioprotection of ischemia-reperfusion injury by cholesterol-dependent MG53-mediated membrane repair. Circ Res. 2010 Jul 9; 107(1):76-83. (IF=15.862)
  23. Chun-Mei Cao, Yan Zhang, Noah Weisleder, Christopher Ferrante, XianhuaWang, Fengxiang Lv, Yi Zhang, Ruisheng Song, Moonsun Hwang, Li Jin, Jiaojiao Guo, Wei Peng, Geng Li, Miyuki Nishi, Hiroshi Takeshima, Jianjie Ma, and Rui-Ping Xiao*. MG53 constitutes a primary determinant of cardiac ischemic preconditioning. Circulation. 2010 Jun 15; 121(23):2565-74. (IF= 23.054)