主要从事抗过敏药物筛选及过敏性疾病机制研究。
发表SCI论文31篇,其中以第一作者/共同第一作者发表7篇。
- Zhang YJ, Xue ZY, Hu SL, et al. Chrysin Inhibits Pseudo-allergic Reaction by Suppressing Mitochondrial STAT3 Activation via MAS-Related GPR Family Member X2. J Agric Food Chem [J]. 2021, 69 (23): 6569-6577.
- Zhang YJ, Hu SL, Wang J, et al. Dexamethasone inhibits SARS-CoV-2 spike pseudotyped virus viropexis by binding to ACE2 [J]. Virology. 2021, 554:83-88. (入选Web of Science高被引论文集)
- Zhang Y, Bai H, Zhang W, et al. miR-212/132 attenuates OVA-induced airway inflammation by inhibiting mast cells activation through MRGPRX2 and ASAP1[J]. Exp Cell Res. Epub ahead of print.
- Zhang YJ, Wang J, Ge S, et al. Roxithromycin inhibits compound 48/80-induced pseudo-allergy via the MrgprX2 pathway both in vitro and in vivo. Cell Immunol [J]. 2020, 358: 104239.
- Zhang YJ, Hu SL, Ge S, et al. Paeoniflorin inhibits IgE-mediated allergic reactions by suppressing the degranulation of mast cells though binding with FcϵRI alpha subunits. Eur J Pharmacol [J]. 2020, 886: 173415.
- Xue ZY*, Zhang YJ*, Zeng YN, et al. Licochalcone A inhibits MAS-related GPR family member X2-induced pseudo-allergic reaction by suppressing nuclear migration of nuclear factor-κB. Phytother Res. 2021 Nov;35(11):6270-6280.
- 王楠, 吴媛媛, 张永竟, 王珏. 柯因在制备抗类过敏药物中的应用 [P]. ZL2020101002902, 中华人民共和国国家知识产权局, 2021.
- 王楠, 贺浪冲, 王程, 王珏, 张永竟. 一种P物质诱导的过敏性哮喘动物模型的构建方法和筛选药物的方法 [P]. ZL2019106001513, 中华人民共和国国家知识产权局, 2020.