校内登录
个人信息 更多+

刘乐

博士生导师 硕士生导师

  • 学历: 博士研究生毕业
  • 学位: 博士
  • 所在单位: 化学学院
  • 电子邮箱:
  • 办公地点: 中国西部科技创新港19-号楼4128

Publications

当前位置: 中文主页 - 发表论文(Publications) - Publications

56. Qi Jiang, Ruixiang Wang, Junhua Xu, Mingyou Hu, Xin-Hua Duan, Le Liu* Photoredox-catalyzed direct formylation of alkenes to access α,β-unsaturated aldehydes. Chem. Sci. 2026https://doi.org/10.1039/D6SC05707A

江琦.png

55. Ruiying Zhao, Youkang Zhou, Mingyou Hu, Xin-Hua Duan, Le Liu* Recent Advances in Visible-Light-Mediated Acylation of Unsaturated Hydrocarbons.Chin. J. Chem. 2026, 44, 3192-3238.

CJC.png

54. Junhua Xu, Keyuan Zhang, Chonglong He, Xin-Hua Duan, Le Liu*, Recent Progress in Sulfonyl Derivative Mediated Radical Aryl Migration. Chin. J. Org. Chem. 2026, 46, 1255-1283. Invited paper.


 


53. Xin Liu, Shanben Yin, Xinxin Han, Jiaxi Cai, Qiaoya Wang, Le Liu, Xin-Hua Duan and Mingyou Hu, Crosslinked porphyrin–copper polymer catalyzed hydroboration of alkynes and alkenes. Org. Chem. Front., 2026, doi.org/10.1039/D6QO00365F


                                               


 

52. Keyuan Zhang, Min Wang, Qi, Jiang, Bowu Dong, Xinhua Duan, Le Liu* Oxime ester as bifunctional reagent for the alkylamination of alkynes via C-entered radical addition and N-centered radical migration, Sci. China Chem. 2026, 69(2): 858–862。

                                                


 

51. Min Wang, Qi Jiang, Chonglong He, Xin-Hua Duan, Le Liu* Bis(sulfone) as Bifunctional Reagent for the Alkylarylation of Alkenes and Alkynes under Photoredox Conditions, Org. Lett. 2025, 27, 11324-11331.

                                                          


 

50. Xin Liu, Xinxin Han, Jiaxi Cai, Qiaoya Wang, Le Liu, Xin-Hua Duan, Mingyou Hu, Hierarchical phosphorus-enriched organic polymer supports for immobilized palladium catalysts: enabling green and efficient Buchwald–Hartwig amination, Green Chem., 2025, 27, 9522-9530.

Green.png


 

49. Qi Jiang, Keyuan Zhang, Mingyou Hu, Xin-Hua Duan, Le Liu*, Visible-Light-Driven Photoredox-Catalyzed Radical Cyclization via a TEMPO-Intercepted Cascade: Regioselective and Access to Cyclopentene Skeletons, Org. Lett.2025, 27, 10088-10092.


                                                 


 

 48. Xin Liu, Xinxin Han, Jiaxi Cai, Qiaoya Wang, Le Liu, Xin-Hua Duan, Mingyou Hu, Hierarchical phosphorus-enriched organic polymer supports for immobilized palladium catalysts: enabling green and efficient Buchwald–Hartwig amination, Green Chem. 2025, 27, 9522-9530.

                                              


 

47. Xinxin Han, Xin Liu, Christophe Len, Le Liu, Xin-Hua, Duan, Mingyou Hu, Visible-light-driven gem-difluorocyclopropanation of gem-difluoroalkenes with diazo compounds, Tetradedron 2025, 180, 134653.

 

                                            

 

46. Jiaxi Cai, Huanghuan Song, Xin Liu, Haixia Song, Le Liu, Xin-Hua Duan, Mingyou Hu, gem-Difluoroalkenylation of aldehydes and ketones with bis(difluoromethyl) triphenylphosphorane under operationally simple conditions, Tetradedron 2025, 173, 134461.

 

                                                             

 

45. Youkang Zhou, Ruiying Zhao, Mingyou Hu, Xin-Hua Duan and Le Liu* Photoredox-Catalyzed Alkene Acylesterification with Acyloxime Esters via C-C and Tertiary C-O Bond formation.Org. Lett. 2025, 27, 623-628

                                                                      

 

 

44. Chonglong He, Youkang Zhou, Xin-Hua Duan, Le Liu*, Application of Functional Group Migration Strategies in Photodriven Difunctionalization of Unsaturated Hydrocarbons, Chin. J. Org. Chem.2025, 45,1478-1508 (Invited paper)

                                                            

  

43. Keyuan Zhang, Qi Jiang, Chonglong He, Mingyou Hu, Yangyang Cheng, Xin-Hua Duan, Le Liu*, Photoredox Catalyzed Conia-Ene-Type Cyclization/SmilesRearrangement Cascade Reactions to Access SubstitutedMethylenecarbocycles, Org. Lett.2024, 26, 7971-7975

                                


 42. Wen-Peng Yang, Hong-Jie Miao, Le Liu, Xin-Hua Duan, Li-Na Guo, Visible Light-Promoted Aromatization-Driven Deconstructive Fluorination of Spiro Carbocycles, Org. Lett.2024, 26, 7442-7446.

                                                                

 

41. Qing Guo, Jun-Lin Lu, Bin Qin, Qi-Chao Shan, Le Liu, Jin-Dan Zhang, Xi, Liu, Xin-Hua Duan, Li-Na Guo, Facets in metal halide perovskite nanocrystals for the photoinduced electron transfer annulation reaction,J. Mater. Chem. A, 2024, 12, 23406-23410.

 

 

40. Chonglong He, Yulong Wang, Quan-Xin Li, Zichen Yan, Keyuan Zhang, Shao-Fei Ni, Xin-Hua Duan, Le Liu* Alkylarylation of alkenes with arylsulfonylacetate as bifunctional reagent via photoredox radical addition/smiles rearrangement cascade,Chin. Chem. Lett., 2024, 36, 110235.

                                                

 

39. Youkang Zhou, Qi Jiang, Yangyang Cheng, Mingyou Hu, Xin-Hua Duan, Le Liu* Photoredox Catalyzed Acylchlorination of α-CF3 Alkenes with Acyl Chloride and Application as Masked Access to b-CF3-enones, Org. Lett.2024, 26, 2656–2661

 

                                            

 38. Xiaoying Wang, Jiaxi Cai, Haixia Song, Le Liu, Xin-Hua Duan, Mingyou Hu*, Electrocatalysis-Enabled Stereoselective Synthesis of Monofluoroalkenes via Hydrodefluorination of gem-Difluoroakenes, Org. Lett.2024, 26, 1635–1639.

                                                       

 

37. Ting Xue, Cheng Ma, Le Liu, Chunhui Xiao,* Shao-Fei Ni,* Rong Zeng,* Characterization of A π–π Stacking Cocycrystal of 4-Nitrophthalonitrile Directed Toward Application in Photocatalysis.Nat.Commun.2024,15, 2455.

                                           

36. Haixia Song, Qin Wang, Xingjie, Ruan, Weilong Hu, Le Liu, Xin-Hua Duan, Mingyou Hu, The synthesis of N-Trifluoromethyl hydroxylamine from (trifluoromethyl)trimethylsilane, J. Fluorine Chem. 2024, 280, 110356.

 

                                                          

 

35. Wenpeng Yang, Hongjie Miao, Le Liu, Xin-Hua Duan, Li-Na Guo, Visible Light-Promoted Aromatization-Driven Deconstructive Fluorination of Spiro Carbocycles, Org. Lett.2024, 26, 7442-7446.

 

                                                         


 

34. Xiaoying Wang, Rui Zhang, Jiaxi Cai, Xin Liu, Haixia Song, Le Liu, Xin-Hua Duan, Mingyou Hu, Streamlined Electrochemical Dihalogenation (F, Cl, and Br) of gem-Difluoroalkenes Using Hydrogen Halides as Reagents, Eur. J. Org. Chem. 2024, 27, e202400351.

 

                                                          

 

33. Wenpeng Yang, Hongjie Miao, Gang Wang, Xiaoyu Yang, Xianjun Wang, Le Liu, Xin-Hua Duan, Li-Na Guo, Photoinduced Aromatization-Driven Deconstructive Fluorosulfonylation of Spiro Dihydroquinazolinones, J. Org. Chem. 2024, 89, 18713-18722.

 

                                                        

 32. Chonglong He, Min Wang, Yulong Wang, Lirong Zhao, Youkang Zhou, Keyuan Zhang, Shenyu Shen, Yaqiong Su, Xin-Hua Duan and Le Liu* Photoredox catalytic alkylarylation of alkynes with arylsulfonylacetate as bifunctional reagent, Sci. China Chem.2024, 67, 2022-2028.

 

                                     

       

31. Chonglong He, Min Wang, Bowu Dong, Yaqiong Su, Xin-Hua Duan, and Le Liu*, Lone pair-π interaction induced regioselective sulfonation of ethers under light irradiation, Green. Synth. Catal.2024, 5, 117-212.

                                             



 

30. Yurou Zhao,  Zhiyong Ma, Le Liu, Pin Gao, Xin-Hua Duan and Mingyou Hu. Synthesis of a-Difluoromethylene Ethers via Photoredox-Induced Hyperconjugative Ring Opening of gem-Difluorocyclopropanes. J. Org. Chem.2023, 88, 3787-3793.

                                                      


 

 29. Youkang Zhou, Lirong Zhao, Mingyou Hu, Xin-Hua Duan and Le Liu* Visible-Light Photoredox Catalyzed Divergent 1,2-Diacylation and Hydroacylation of Alkenes with Carboxylic Acid Anhydride. Org. Lett. 2023, 5268–5272


                                            

 28. Ying-Jie Ma, Zi-Hang Yuan, Pin Gao, Xin-Hua Duan, Hong Xin, Le Liu and Li-Na Guo* Divergent Construction of Azaheterocycles via Alkoxyl Radical-Triggered C-C Bond Cleavage/Cyclization of N-Functionalized Acrylamides. J. Org. Chem. 2023, 9927–9940

                                            

 

27.  Yulong Wang, Shenshen Yu, Chonglong He, Youkang Zhou, Keyuan Zhang, Bin Rao, Tian Han, Yaqiong Su, Xin-Hua Duan, Le Liu*, Cu(II)-mediated direct intramolecular cyclopropanation of distal olefinic acetate: access to cyclopropane-fused g-lactone, Chem. Sci. 2023, 14, 6663-6668.

                                          

 26. Shuai Liu, Pengchen Ma, Lu Zhang, Shenyu Shen, Hong-Jie Miao, Le Liu, K. N. Houk, Xin-Hua Duan Li-Na Guo* A Cheap Metal Catalyzed Ring Expansion/Cross-Coupling Cascade: A New Route to Functionalized Medium-Sized and Macrolactones. Chem. Sci.2023,14, 5220-5225.

 

                                         

 

25. Dan-Ning Wang, Qi Lin, Xun Wang, Keyuan Zhang, Xin-Hua Duan, Le Liu* Visible-Light Induced Oxidative Annulation of Enamides to 2,4,5-Trisubstituted Oxazole Skeletons, Asian J. Org. Chem.2023, 12, e202300019 (Cover Paper).


 

                                           

                                                           

     

24. Xinxin Han, Xin Liu, Yueyun Bao, Huanhuan Song, YurouZhao, Xiaoying Wang, Junjie Zhang, Le Liu, Xin-Hua Duan, Jinbo Hu and Mingyou Hu. Water-promoted regio-selective trifluoromethylation of vinyl conjugated diazoacetates. Org. Chem. Front. 2022, 9, 204-209.


     


  

23. Keyuan Zhang, Yulong Wang, Chonglong He, Youkang Zhou, Danning Wang, Mingyou Hu, Xin-Hua Duan, Le Liu*, Halogen bond promoted aryl migration of allylic alcohols under visible light irradiation, Org. Chem. Front.2022, 9, 5599-5605

                                      

 22. Chonglong He, Keyuan Zhang, Dan-Ning Wang, Min Wang, Yuejie Niu, Xin-Hua Duan and Le Liu* Metal-Free Visible-Light-Induced Alkylarylation of Unactivated Alkenes via Radical Addition/Truce-Smiles Rearrangement Cascade, Org. Lett.  2022, 24, 2767–2771.

                                      

 

  21.Keyuan Zhang, Tianbing Liang, Yulong Wang, Chonglong He, Xin-Hua Duana and Le Liu* Oxidative thiocyanation of allylic alcohols: an easy access to allylic thiocyanates with K2S2O8 and NH4SCN, Org. Chem. Front. 2022, 9, 966-972.

                                          

 

20. Le Liu, Xin-Hua Duan and Li-Na Guo, Recent Advance in Iminyl-Radical-Triggered C−H and C−C Bond Functionalization of Oxime Esters via 1,5-HAT and β-Carbon Scission, Synthesis 2021, 53, 4375-4388 (Invited paper, Cover paper)

                                        

 

19. Le Liu and Cristina Nevado* Diaryl Ether Formation Merging Photoredox and Nickel Catalysis, Organometallics 2021, 40, 2188-2193.

                                                

 

18. Li Chen, Li-Na Guo, Shuai Liu, Le Liu and Xin-Hua, Duan* Visible-light-driven palladium-catalyzed Dowd–Beckwith ring expansion/C–C bond formation cascade, Chem. Sci. 2021,12, 1791-1795.

                                                


 

17. Zhi-Yong Ma, Mengyang Li, Li-Na Guo, Le Liu, Dongdong Wang and Xin-Hua Duan*, Sulfonamide as Photoinduced Hydrogen-Atom Transfer Catalyst for Regioselective Alkylation of C(sp3)–H Bonds Adjacent to Heteroatoms, Org. Lett. 2021, 23, 2, 474–479

                                                

 16.   Yinan Zheng, Ying You, Qianqian Shen, Le Liu,* and Xin-Hua Duan*, Visible-Light-Induced Anti-Markovnikov Hydrosulfonation of Styrene Derivatives, Org. Chem. Front. 2020, 7, 2069-2074

                                               


 15. Hong Xin, Xin-Hua Duan, Le Liu, Li-Na Guo, Metal‐free, Visible Light‐induced Selective C‐C Bond Cleavage of Cycloalkanones with Molecular Oxygen,Chem. Eur. J.2020, 26, 11690-11694.  



Before XJTU


14.      Xiang Zhang, Xiaoyu Hao, Le Liu, Anh-Tuan Pham, Javier López-Andarias, Antonio Frontera, Naomi Sakai , and Stefan Matile* Primary Anion-π Catalysis and Autocatalysis J. Am. Chem. Soc. 2018, 140, 17867-17871.


                                                                 

 


13.      Yingjie Zhao, Yoann Cotelle, Le Liu, Javier, López-Andarias, Anna-Bea Bornhof, Masaaki Akamatsu, Naomi Sakai, Stefan Matile* The Emergence of Anion-π CatalysisAcc. Chem. Res. 2018, 51, 2255-2263

                                                    

  

12.      Xiang Zhang,† Le Liu,† Lopez-Andarias, Chao Wang, Naomi Sakai, Stefan Matile* Anion-π Catalysis: Focus on Nonadjacent stereocenters. Helv. Chim. Acta 2018, 101, e1700288. (co-first author)

                                                                

 

 11.  Le Liu, Yoann Cotelle, Anna-Bea Bornhof, Celine Besnard, Naomi Sakai and Stefan Matile* Anion-π Catalysis of Diels-Alder Reactions. Angew. Chem. Int. Ed. 2017, 56, 13066-13069 (Hot Paper)

 

                                 


 

10. Le Liu, Yoann Cotelle, Vincent Lebrun, Naomi Sakai, Thomas R. Ward and Stefan Matile* Anion-π Catalysis: Bicyclic Products with Four Contiguous Stereogenic Centers from Otherwise Elusive Diastereospecific Domino Reactions on π-Acidic Surfaces. Chem. Sci. 2017, 8, 3770-3774.

                                                     

 

9.   Le Liu and Stefan Matie* Anion-π transaminase mimics. Supramol. Chem. 2017, 29, 702-706.

                                                             


8.       Le Liu, Yuann, Cotelle; Alyssa-Jennifer, Avestro; Naomi, Sakai and Stefan Matile* Asymmetric Anion-π Catalysis of Iminium/Nitroaldol Cascades to Form Cyclohexane Rings with Five Stereogenic Centers Directly on π-Acidic Surfaces. J. Am. Chem. Soc. 2016, 138, 7876-7879.


 

                                            

 

7.        Le Liu, Tonghuan, Zhang; Yun-Fang, Yang; Daisy Zhang-Negrerie; Xinhao Zhang, Yunfei Du;* Yun-Dong Wu* and Kang Zhao* Metal-Free Synthesis of 3‑Arylquinolin-2-ones from Acrylic Amides via a Highly Regioselective 1,2-Aryl Migration: An Experimental and Computational Study. J. Org. Chem. 2016, 81, 4058-4065.

                                                                



6.   Le Liu; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* Hypervalent Iodine Mediated C-C Double Bond Activation:A Cascade Access to a-Keto Diacetates from Readily Available Cinnamic Acids. Synthesis, 2015, 47, 2924-2930 (Invited Paper).

                            

 

5.     Le Liu; Liang, Du; Daisy Zhang-Negrerie and Yunfei Du* NIS-mediated intramolecular oxidative a-functionalization of tertiary amines: transition metal-free synthesis of 1,2-dihydro-(4H)-3,1-benzoxazin-4-one derivatives. RSC Adv. 2015, 5, 29774-29781.


                                          

 


4.     Le Liu; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* PhICl2 and Wet DMF: An Efficient System for Regioselective Chloroformyloxylation/a-hlorination of Alkenes/a,baturated Compounds. Org. Lett. 2014, 16, 436-439.

 

                                     

 


3.     Le Liu; Liang, Du; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* Metal-Free Tandem Oxidative Aryl Migration and C−C Bond Cleavage: Synthesis of a-Ketoamides and Esters from Acrylic Derivatives. Org. Lett. 2014, 16, 5772-5775.

 

                                      

 

 


2.     Le Liu; Hang, Lu; Hong, Wang; Chao, Yang; Xiang, Zhang; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* PhI(OCOCF3)2‑Mediated C-C Bond Formation Concomitant with a 1,2-Aryl Shift in a Metal-Free Synthesis of 3‑Arylquinolin-2-ones. Org. Lett. 2013, 15, 2906-2909.

 

                                               

 

1.   Le Liu; Yanfeng, Fan; Qiaoqiao, He; Yun, Zhang; Daisy Zhang-Negrerie; Jianhui, Huang,* Yunfei Du* and Kang Zhao Synthesis of Functionalized Fluorescent Indenes from Electron-Rich α-Aryl Ketonitriles J. Org. Chem. 2012, 77, 3997-4004.