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赵四海

电子邮箱:
所在单位:基础医学院
职务:动物中心 书记/常务副主任
学历:博士研究生毕业
办公地点:1. 雁塔校区SPF楼2楼208
2. 创新港22号楼2楼S234
性别:男
联系方式:
学位:博士
职称:教授
博士生导师:是
硕士生导师:是
学科:基础医学
刘浩乐 博士生

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         刘浩乐  

博士研究生(2021.09至        )

        

发表论文:

  1.  Liu H#, Tian K#, Fu W#, Qin L, Tian R, Wei P, Zou J, Alam N, Malik F, Li K, Li M, Xu B, Guo J, Xia C, Wang R, Wang W, Bai L, Liu E, Xu B, Li Y, Zhao S. Tranilast ameliorates experimental abdominal aortic aneurysm by inhibiting the NLRP3 inflammasome pathway. J Pharm Anal. 2026;16(3): 101453.  # co-first authors.  IF=11.2  

  2.  Liu H, Zhang J, Xue Z, Chang M, Feng X, Cai Y, Bai L, Wang W, Liu E, Zhao S, Wang R. Deficiency of protein inhibitor of activated STAT3 exacerbates atherosclerosis by modulating VSMC phenotypic switching. Atherosclerosis. 2023;380:117195. IF=7.1

  3. Liu H#, Qin L#, Zou J, Tian K, Li K, Tian R, Malik F, Wei P, Xia C, Hou H, Cai T, Meng Y, Liu E, Xu B, Zhao S. Intra-aortic infusion of nicotine can induce a novel mouse model of abdominal aortic aneurysm. Eur J Pharm Sci. 2025;211:107143. IF=5.1

  4. Liu H, Wei P, Fu W, Xia C, Li Y, Tian K, Li Y, Cheng D, Sun J, Xu Y, Lu M, Xu B, Zhang Y, Wang R, Wang W, Xu B, Liu E, Zhao S. Dapagliflozin Ameliorates the Formation and Progression of Experimental Abdominal Aortic Aneurysms by Reducing Aortic Inflammation in Mice. Oxid Med Cell Longev. 2022;2022:8502059. IF=7.3

  5. Liu H, Tian K, Xia C, Wei P, Xu B, Fu W, Li Y, Li Y, Bai L, Wang R, Wang W, Xu B, Liu E, Zhao S. Kunming mouse strain is less susceptible to elastase-induced abdominal aortic aneurysms. Animal Model Exp Med. 2022;5(1):72-80. IF=3.3

  6. Fu Y#, Liu H#, Li K, Wei P, Alam N, Deng J, Li M, Wu H, He X, Hou H, Xia C, Wang R, Wang W, Bai L, Xu B, Li Y, Wu Y, Liu E, Zhao S. C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms. Front Immunol. 2023;14:1233807.  IF=7.0

  7. Fu W#, Liu H#, Wei P, Xia C, Yu Q, Tian K, Li Y, Liu E, Xu B, Miyata M, Wang R, Zhao S. Genetic deficiency of protein inhibitor of activated STAT3 suppresses experimental abdominal aortic aneurysms. Front Cardiovasc Med. 2023;10:1092555.  IF=3.0

  8. Tian K, Tian R, Qin L, Liu H, Malik F, Wei P, Zou J, Li K, Hou H, Sun K, Wang R, Wang W, Bai L, Xu B, Liu E, Zhao S. Animal studies and AI-based analysis identify the efficacy of berberine to inhibit experimental abdominal aortic aneurysms. Phytomedicine. 2025;147:157176.  IF=11.3

  9. Yu QQ, Cheng DX, Xu LR, Li YK, Zheng XY, Liu Y, Li YF, Liu HL, Bai L, Wang R, Fan JL, Liu EQ, Zhao SH. Urotensin II and urantide exert opposite effects on the cellular components of atherosclerotic plaque in hypercholesterolemic rabbits. Acta Pharmacol Sin. 2020;41(4):546-553.  IF=10.4

  10. Li K, Li M, Wei P, Tian K, Liu H, Fu W, Hou H, Chen Y, Xu B, Li Y, Zhao S. Cysteine Leukotriene Receptor Antagonist-Montelukast-Treatment Improves Experimental Abdominal Aortic Aneurysms in Mice. Cardiovasc Ther. 2024:8826287.   IF=2.8

  11. Li M, Wei P, Li K, Liu H, Alam N, Hou H, Deng J, Xu B, Liu E, Zhao S, Li Y. The incidence rate and histological characteristics of intimal hyperplasia in elastase-induced experimental abdominal aortic aneurysms in mice. Animal Model Exp Med. 2024;7(3):388-395.  IF=3.3

  12. Tian K, Xia C, Liu H, Xu B, Wei P, Fu W, Lu M, Li Y, Li Y, Cheng D, Liu E, Zhao S. Temporal and Quantitative Analysis of Aortic Immunopathologies in Elastase-Induced Mouse Abdominal Aortic Aneurysms. J Immunol Res. 2021:6297332.  IF=3.2

  13. Wei P, Tian K, Liu H, Li K, Alam N, Cheng D, Li M, He X, Guo J, Wang R, Wang W, Bai L, Liu E, Xu B, Li Y, Zhao S. Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway. Biochim Biophys Acta Mol Basis Dis. 2024; 1870(5):167170.  IF=5.0

  14. Wei P, Li K, Li M, Liu H, Xia C, Chen Y, Zhao S, Li Y. The C57BL/6N mouse substrain is a viable model of elastase-induced abdominal aortic aneurysm. Front Cardiovasc Med. 2024;11: 1462032. IF=3.0

  15. Yu Q, Wei P, Xu L, Xia C, Li Y, Liu H, Song X, Tian K, Fu W, Wang R, Wang W, Bai L, Fan J, Liu E, Zhao S. Urotensin II Enhances Advanced Aortic Atherosclerosis Formation and Delays Plaque Regression in Hyperlipidemic Rabbits. Int J Mol Sci. 2023;24(4):3819.  IF=5.6