代表性论文

累积发表第一作者或通讯作者（含共同）SCI/EI期刊50篇，其中IF>10或细分领域Q1区顶级期刊38篇，2篇论文入选ESI热点论文（TOP 0.1%），6篇论文入选ESI高被引论文（Top 1%），H指数28，累计影响因子超过600，引用次数超过1900次。代表性文章如下：

 

  1. Liu D#, Yan J#,*, Ma F, Wang J, Yan S, He W*. Reinvigoration of cytotoxic T lymphocytes in microsatellite instability-high colon adenocarcinoma through lysosomal degradation of PD-L1. Nature Communications. 2024, 15(1): 6922. [IF=14.7, JCR Q1] (末位通讯)
  2. He W#,*, Wang Y#, Li X#, Ji Y, Yuan J, Yang W, Yan S, Yan J*. Sealing the Pandora’s vase of pancreatic fistula through entrapping the digestive enzymes within a dextrorotary (D)-peptide hydrogel. Nature Communications. 2024, 15(1): 7235. [IF=14.7, JCR Q1] (一作兼通讯)
  3. Yan J#,*, Liu D#, Wang J, You W, Yang W, Yan S, He W*. Rewiring chaperone-mediated autophagy in cancer by a prion-like chemical inducer of proximity to counteract adaptive immune resistance. Drug Resistance Updates. 2024, 73: 101037. [IF=15.8, JCR Q1, ESI热点] (末位通讯)
  4. Liu N#, Zheng X#, Yan J#, Jiang A, Yao Y, He W*. Reversing MET-Mediated Resistance in Oncogene-Driven NSCLC by MET-Activated Wnt Condensative Prodrug. Advanced Science. 2024, 11(30): e2400603. [IF=14.3, JCR Q1] (唯一通讯)
  5. Liu W*, Ding F, Yang W, You W, Zhang L, He W*. A Transdermal Prion-Bionics Supermolecule as a RAB3A Antagonist for Enhancing Facial Youthfulness. Advanced Science. 2024, 11(30): e2308764. [IF=14.3, JCR Q1] (末位通讯)
  6. Jiang A, Zheng X, Yan S, Yan J*, Yao Y*, He W*. Advancing the Boundaries of Immunotherapy in Lung Adenocarcinoma with Idiopathic Pulmonary Fibrosis by a Biomimetic Proteinoid Enabling Selective Endocytosis. ACS Nano. 2024, 18(7): 5358–5373. [IF=15.8, JCR Q1] (末位通讯)
  7. Ren M#, Wang Y, # Zheng X, Yang W, Liu M, Xie S, Yao Y, Yan J, He W*. Hydrogelation of peptides and carnosic acid as regulators of adaptive immunity against postoperative recurrence of cutaneous melanoma. J Control Release. Published online September 19, 2024. [IF=10.5, JCR Q1] (唯一通讯)
  8. Li F #, Wang J#, Liu T#, Yang W, Li Y, Yan J*, He W*. Rebooting the adaptive immune response in immunotherapy-resistant lung adenocarcinoma using a supramolecular albumin. Small. 2024. (in press) [IF=13.0, JCR Q1] (末位通讯)
  9. Yang W#, Liu W#*, Li X#, Yan J*, He W*. Turning chiral peptides into a racemic supraparticle to induce the self-degradation of MDM2. J Adv Res. 2023,45:59-71. [IF=11.4, JCR Q1, ESI高被引] (末位通讯)
  10. Wang J#, Zheng X#, Fu X#, Jiang A, Yao Y, He W*. A de novo dual-targeting supramolecular self-assembly peptide against pulmonary metastasis of melanoma. Theranostics. 2023, 13(11): 3844-3855. [IF=12.4, JCR Q1] (唯一通讯)
  11. Yan, J#,*, Yao Y#, Yan S, Gao R, Lu W*, He W*. Chiral protein supraparticles for tumor suppression and synergistic immunotherapy: an enabling strategy for bioactive supramolecular chirality construction. Nano Letters. 2020, 20(8): 5844-5852. [IF(当年/最新)=11.189/9.6, JCR Q1, ESI高被引] (末位通讯)
  12. Yan S#, Yan J#,*, Liu D#, Li X#, Kang Q, You W, Zhang J, Wang L, Tian Z, Lu W*, Liu W*, He W*. A nano-predator of pathological MDMX construct by clearable supramolecular gold(I)-thiol-peptide complexes achieves safe and potent anti-tumor activity. Theranostics. 2021, 11(14): 6833-6846. [IF(当年/最新)=11.6/12.4, JCR Q1, ESI高被引] (末位通讯)
  13. She J#,*, Li Y#, Yan S, Yan Y, Liu D, Li S, Guo Y, Xue Y, Yao Y, Yan J*, He W*. De novo supraparticle construction by a self-assembled Janus cyclopeptide to tame hydrophilic microRNA and hydrophobic molecule for anti-tumor cocktail therapy and augmented immunity. Chemical Engineering Journal. 2020, 401: 126080. [IF(当年/最新)=13.273/13.3, JCR Q1] (末位通讯)
  14. Yan J#, Ji F#, Yan S#, You W, Ma F, Li F, Huang Y*, Liu W*, He W*. A general-purpose Nanohybrid fabricated by Polymeric Au(I)-peptide precursor to wake the function of Peptide Therapeutics. Theranostics. 2020, 10(19): 8513-8527. [IF(当年/最新)=11.556/12.4, JCR Q1] (末位通讯)
  15. Bian Z#, Yan J#, Wang S#, Li Y, Guo Y, Ma B, Guo H, Lei Z, Yin C, Zhou Y, Liu M, Tao K*, Hou P*, He W*. Awakening p53 in vivo by D-peptides-functionalized ultra-small nanoparticles: Overcoming biological barriers to D-peptide drug delivery. Theranostics. 2018, 8(19): 5320-5335. [IF(当年/最新)=8.063/12.4, JCR Q1] (末位通讯)
  16. He W#,*, Yan J#, Sui F#, Wang S, Su X, Qu Y, Yang Q, Guo H, Ji M, Lu W, Shao Y*, Hou P*. Turning a luffa protein into a self-assembled biodegradable nanoplatform for multitargeted cancer therapy. ACS Nano. 2018, 12(11): 11664-11677. [IF(当年/最新)=13.903/15.8, JCR Q1] (第一兼共通)

  1. He W#,*, Zhang Z#, Yang W, Zheng X, You W, Yao Y, Yan J*, Liu W*. Turing milk into pro-apoptotic oral nanotherapeutic: De novo bionic chiral-peptide supramolecule for cancer targeted and immunological therapy. Theranostics. 2022,12(5):2322-2334. [IF(当年/最新)=12.4/12.4, JCR Q1] (第一兼共通)
  2. He W#, Yan J#,*, Li Y#, Yan S, Wang S, Hou P*, Lu W*. Resurrecting a p53 peptide activator - An enabling nanoengineering strategy for peptide therapeutics. Journal of Controlled Release. 2020, 325: 293-303. [IF(当年/最新)=9.776/10.5, JCR Q1] (第一作者)
  3. He W#, Wang S#, Yan J#, Qu Y, Jin L, Sui F, Li Y, You W, Yang G, Yang Q, Ji M, Shao Y, Ma PX*, Lu W*, Hou P*. Self-assembly of therapeutic peptide into stimuli-responsive clustered nanohybrids for cancer-targeted therapy. Advanced Functional Materials. 2019, 29(10): 1807736. [IF(当年/最新)=16.836/18.5, JCR Q1] (第一作者)
  4. He W#, Yan J#, Wang L#, Lei B, Hou P*, Lu W*, Ma PX*. A lanthanide-peptide-derived bacterium-like nanotheranostic with high tumor-targeting, -imaging and -killing properties. Biomaterials. 2019, 206: 13-24. [IF(当年/最新)=10.317/12.8, JCR Q1] (第一作者)
  5. He W#, Yan J#, Jiang W#, Li S, Qu Y, Niu F, Yan Y, Sui F, Wang S, Zhou Y, Jin L, Li Y, Ji M, Ma PX, Liu M*, Lu W*, Hou P*. Peptide-induced self-assembly of therapeutics into a well-defined nanoshell with tumor-triggered shape and charge switch. Chemistry of Materials. 2018, 30(20): 7034-7046. [IF(当年/最新)=10.159/7.2, JCR Q1] (第一作者)
  6. Li L#, He W#,*, You W, Yan J*, Liu W*. Turing miRNA into infinite coordination supermolecule: a general and enabling nanoengineering strategy for resurrecting nuclear acid therapeutics. Journal of Nanobiotechnology. 2022, 20(1): 10. [IF(当年/最新)=10.2/10.6, JCR Q1, ESI高被引] (共一兼共通)
  7. Yan J#, He W#,*, Yan S#, Niu F, Liu T, Ma B, Shao Y, Yan Y, Yang G, Lu W, Du Y, Lei B*, Ma PX. Self-assembled peptide-lanthanide nanoclusters for safe tumor therapy: overcoming and utilizing biological barriers to peptide drug delivery. ACS Nano. 2018,12(2):2017-2026. [IF(当年/最新)=13.903/15.8, JCR Q1, ESI高被引] (共一兼共通)
  8. Yan J#,*, He W#,*, Li X#, You W, Liu X, Lin S, Chen J, Zhao Y, Zhang Y*, Ji F*. Carnosic acid-induced co-self-assembly of metal-peptide complexes into a nanocluster-based framework with tumor-specific accumulation for augmented immunotherapy. Chemical Engineering Journal. 2021, 416: 129141. [IF(当年/最新)=16.744/13.3, JCR Q1] (共一兼共通)
  9. Yang W#, Li Z#, Li Y, He W*, Yan J*. Transforming Albumin into a Trojan Horse of Immunotherapy-Resistant Colorectal Cancer with a High Microsatellite Instability. ACS Nano. 2024;18(29):19332-19344. [IF=15.8, JCR Q1] (共同通讯)
  10. Yan J*, Zheng X, You W, He W*, Xu G*. A bionic-homodimerization strategy for optimizing modulators of protein–protein interactions: from statistical mechanics theory to potential clinical translation. Advanced Science. 2022, 2105179. [IF(当年/最新)=15.1/14.3, JCR Q1, ESI高被引] (共同通讯)
  11. Li X, Wang Y, Yuan J, An J, Yan S, Wu W, He W*, Yan J, Tao K. Chiral D-peptide supramolecular hydrogel for minimizing postoperative pancreatic fistula by devitalizing pancreatic enzymes. Chemical Engineering Journal. 2024, 482: 149069. [IF=13.3, JCR Q1] (共同通讯)
  12. Yuan J, Wang Y, Yang W, Li X, Tao K, He W*, Yan J*. Biomimetic peptide dynamic hydrogel inspired by humanized defensin nanonets as the wound-healing gel coating. Chemical Engineering Journal. 2023, 470: 144266. [IF=15.1, JCR Q1，ESI热点] (共同通讯)
  13. Ma F#, Liu T#, Yang W#, You W, He W*, Yan J*, Liu W*. Turning Fluvastatin into a supramolecular immuno-sensitizer towards augmented tumor immunotherapy. Chemical Engineering Journal. 2022,437:135310. [IF(当年/最新)=15.1/13.3, JCR Q1] (共同通讯)

  1. Liu T#, Yan J#, He C#, You W, Ma F, Chang Z, Li Y, Han S*, He W*, Liu W*. A tumor-targeting metal-organic nanoparticle constructed by dynamic combinatorial chemistry toward accurately redressing carcinogenic Wnt cascade. Small. 2022, 18(3): 2104849. [IF(当年/最新)=13.3/13, JCR Q1] (共同通讯)
  2. Yan J#, Zhang L#, Li L, He W*, Liu W*. Developmentally engineered bio-assemblies releasing neurotrophic exosomes guide in situ neuroplasticity following spinal cord injury. Materials Today Bio. 2022, 16: 100406. [IF(当年/最新)=8.2/8.7, JCR Q1] (共同通讯)
  3. Zheng X#, Yan J#,*, You W, Li F, Diao J, He W*, Yao Y*. De novo nano-erythrocyte structurally braced by biomimetic Au(I)-peptide skeleton for MDM2/MDMX predation toward augmented pulmonary adenocarcinoma immunotherapy. Small. 2021,17 (20), 2100394. [IF(当年/最新)=15.153/13, JCR Q1] (共同通讯)
  4. Yan J#,*, Wang Y#, Li X#, Guo D, Zhou Z, Bai G, Li J, Huang N, Diao J, Li Y, He W*, Liu W*, Tao K*. A bionic nano-band-aid constructed by the three-stage self-assembly of peptides for rapid liver hemostasis. Nano Letters. 2021, 21(17):7166-7174. [IF(当年/最新)=12.262/9.6, JCR Q1] (共同通讯)
  5. Yan J, Yan S, Hou P, Lu W, Ma PX, He W*, Lei B*. A hierarchical peptide–lanthanide framework to accurately redress intracellular carcinogenic protein–protein interaction. Nano Letters. 2019, 19(11): 7918-7926. [IF(当年/最新)=11.283/9.6, JCR Q1] (共同通讯)
  6. Liu J#, Yan J#,*, Yan S#, Wang Y, Zhang R, Hou P, He W*, Ji M*. Biomimetic and self-assembled nanoclusters targeting β-catenin for potent anticancer therapy and enhanced immunotherapy. Nano Letters. 2019, 19(12): 8708-8715. [IF(当年/最新)=11.283/9.6, JCR Q1] (共同通讯)
  7. Niu F#, Yan J#, Ma B, Li S, Shao Y, He P, Zhang W, He W*, Ma PX*, Lu W*. Lanthanide-doped nanoparticles conjugated with an anti-CD33 antibody and a p53-activating peptide for acute myeloid leukemia therapy. Biomaterials. 2018, 167: 132-142. [IF(当年/最新)=10.273/12.8, JCR Q1] (共同通讯)
  8. Mi S, Chang Z, Wang X, Gao J, Liu Y, Liu W, He W*, Qi Z*. Bioactive Spinal Cord Scaffold Releasing Neurotrophic Exosomes to Promote In Situ Centralis Neuroplasticity. ACS Appl Mater Interfaces. 2023;15(13):16355-16368. [IF=8.3, JCR Q1] (共同通讯)
  9. Yan J#, He W#, Li N, Yu M, Du Y, Lei B*, Ma PX*. Simultaneously targeted imaging cytoplasm and nucleus in living cell by biomolecules capped ultra-small GdOF nanocrystals. Biomaterials. 2015, 59: 21-29. [IF(当年/最新)=8.387/12.8, JCR Q1] (共同第一作者)