1. Nitroalkanes as Masked Thioacylating Agents to Access Thioamides and Thiopeptides

Xiaonan Wang, Silong Xu, Yuhai Tang, Martin J. Lear, Wanxiao He and Jing Li*

Nature Commun. 2023, doi:10.1038/s41467-023-40334-6.



  1. Highly sterically hindered peptide bond formation between α,α-di-substituted α-amino acids and N-alkyl cysteines using α,α-disubstituted α-amidonitrile.

Xiaoling Wang, Jing Li, Yujiro Hayashi

J. Am. Chem. Soc. 2022, 144, 10145−10150



Before XJTU (Selected publications)


     1. A Chemoselective alpha-Oxytriflation Enables the Direct Asymmetric Arylation of Amides.

      Jing Li, Martin Berger, Wojciech Zawodny, Marwan Simaan, Nuno Maulide*

Chem, 2019, 5, 18831891.

Highlighted by Prof. Timothy R. Newhouse (Chem 2019, 5, 1687-1696)

Highlighted by (

     2. Enantioselective Redox-Neutral Coupling of Aldehydes and Alkenes by an Iron-Catalyzed "Catch-Release" Tethering Approach

Jing Li#, Alexander Preinfalk#, Nuno Maulide*

J. Am. Chem. Soc. 2019, 141, 143147.

Highlighted by SYNFACTS (Synfact 2019, 15, 0385)

Highlighted by OPRD (Org. Process Res. Dev. 2019, 23, 674)

Highlighted by CHEMIE.DE (

     3. alpha-Arylation of Carbonyl Compounds via Oxidative C-C Bond Activation;

Jing Li, Adriano Bauer, Giovanni Di Mauro, Nuno Maulide*

Angew. Chem. Int. Ed. 2019, 58, 98169819.

Highlighted by X-MOL ( and other academic websites)

  4. Diastereo- and Enantioselective Access to Stereotriads through a Flexible Coupling of Substituted Aldehydes and Alkenes.

       Jing Li#, Alexander Preinfalk#, and Nuno Maulide*

Angew. Chem. Int. Ed. 2019, 58, 58875890.

Highlighted by CHEMIE.DE (

     5. A Redox-Neutral Synthesis of Ketones by Coupling of Alkenes and Amides.

Jing Li#, Rik Oost#, Boris Maryasin, Leticia Gonzalez, Nuno Maulide*

Nature Comm. 2019, 10, 2327.


     6. Sterically Demanding Oxidative Amidation of alpha-Substituted Malononitriles with Amines using O2.

Jing Li, Martin J. Lear*, Yujiro Hayashi*

Angew. Chem. Int. Ed. 2016, 55, 90609064.

Highlighted by Organic Chemistry Portal Monday, May 22, 2017


      7. Oxidative Amidation of Nitroalkanes with Amine Nucleophiles using Molecular Oxygen and Iodine.

Jing Li, Martin J. Lear, Yuya Kawamoto, Shigenobu Umemiya, Alice R. Wong, Eunsang Kwon, Itaru Sato, Yujiro Hayashi*

Angew. Chem. Int. Ed. 2015, 54, 12986–12990.

Highlighted by Organic Chemistry Portal Monday, May 23, 2016.