29. Youkang Zhou, Lirong Zhao, Mingyou Hu, Xin-Hua Duan and Le Liu* Visible-Light Photoredox Catalyzed Divergent 1,2-Diacylation and Hydroacylation of Alkenes with Carboxylic Acid Anhydride. Org. Lett. 2023,



28. Ying-Jie Ma, Zi-Hang Yuan, Pin Gao, Xin-Hua Duan, Hong Xin, Le Liu and Li-Na Guo* Divergent Construction of Azaheterocycles via Alkoxyl Radical-Triggered C-C Bond Cleavage/Cyclization of N-Functionalized Acrylamides. J. Org. Chem. 2023,




27.  Yulong Wang, Shenshen Yu, Chonglong He, Youkang Zhou, Keyuan Zhang, Bin Rao, Tian Han, Yaqiong Su, Xin-Hua Duan, Le Liu*Cu(II)-mediated direct intramolecular cyclopropanation of distal olefinic acetate: access to cyclopropane-fused g-lactone, Chem. Sci. 2023, 6663-6668.




26. Shuai Liu, Pengchen Ma, Lu Zhang, Shenyu Shen, Hong-Jie Miao, Le Liu, K. N. Houk, Xin-Hua Duan Li-Na Guo* A Cheap Metal Catalyzed Ring Expansion/Cross-Coupling Cascade: A New Route to Functionalized Medium-Sized and Macrolactones. Chem. Sci. 2023,14, 5220-5225.






25. Dan-Ning Wang, Qi Lin, Xun Wang, Keyuan Zhang, Xin-Hua Duan, Le Liu* Visible-Light Induced Oxidative Annulation of Enamides to 2,4,5-Trisubstituted Oxazole Skeletons, Asian J. Org. Chem. 2023, 12, e202300019 (Cover Paper).








24. Chonglong He, Min Wang, Bowu Dong, Yaqiong Su, Xin-Hua Duan, and Le Liu*, Lone pair-π interaction induced regioselective sulfonation of ethers under light irradiation, Green. Synth. Catal. 2022,





23. Keyuan Zhang, Yulong Wang, Chonglong He, Youkang Zhou, Danning Wang, Mingyou Hu, Xin-Hua Duan, Le Liu*, Halogen bond promoted aryl migration of allylic alcohols under visible light irradiation, Org. Chem. Front. 2022, 9, 5599-5605





22. Chonglong He, Keyuan Zhang, Dan-Ning Wang, Min Wang, Yuejie Niu, Xin-Hua Duan and Le Liu* Metal-Free Visible-Light-Induced Alkylarylation of Unactivated Alkenes via Radical Addition/Truce-Smiles Rearrangement Cascade, Org. Lett.  2022, 24, 2767–2771.



21.Keyuan Zhang, Tianbing Liang, Yulong Wang, Chonglong He, Xin-Hua Duana and Le Liu,* Oxidative thiocyanation of allylic alcohols: an easy access to allylic thiocyanates with K2S2O8 and NH4SCN, Org. Chem. Front. 20229, 966-972.



20. Le Liu, Xin-Hua Duan and Li-Na Guo, Recent Advance in Iminyl-Radical-Triggered CH and CC Bond Functionalization of Oxime Esters via 1,5-HAT and β-Carbon Scission, Synthesis 2021, 53, 4375-4388 (Invited paper, Cover paper)


19. Le Liu and Cristina Nevado* Diaryl Ether Formation Merging Photoredox and Nickel Catalysis, Organometallics 2021, 40, 2188-2193.


18. Li Chen, Li-Na Guo, Shuai Liu, Le Liu and Xin-Hua, Duan* Visible-light-driven palladium-catalyzed Dowd–Beckwith ring expansion/C–C bond formation cascade, Chem. Sci. 2021,12, 1791-1795.


17. Zhi-Yong Ma, Mengyang Li, Li-Na Guo, Le Liu, Dongdong Wang and Xin-Hua Duan*, Sulfonamide as Photoinduced Hydrogen-Atom Transfer Catalyst for Regioselective Alkylation of C(sp3)–H Bonds Adjacent to Heteroatoms, Org. Lett. 2021, 23, 2, 474–479


 16.   Yinan Zheng, Ying You, Qianqian Shen, Le Liu,* and Xin-Hua Duan*, Visible-Light-Induced Anti-Markovnikov Hydrosulfonation of Styrene Derivatives, Org. Chem. Front. 2020, 7, 2069-2074

15. Hong Xin, Xin-Hua Duan, Le Liu, Li-Na Guo, Metal‐free, Visible Light‐induced Selective C‐C Bond Cleavage of Cycloalkanones with Molecular OxygenChem. Eur. J.2020, 26, 11690-11694.




Before XJTU

14.      Xiang Zhang, Xiaoyu Hao, Le Liu, Anh-Tuan Pham, Javier López-Andarias, Antonio Frontera, Naomi Sakai , and Stefan Matile* Primary Anion-π Catalysis and Autocatalysis J. Am. Chem. Soc. 2018, 140, 17867-17871.

13.      Yingjie Zhao, Yoann Cotelle, Le Liu, Javier, López-Andarias, Anna-Bea Bornhof, Masaaki Akamatsu, Naomi Sakai, Stefan Matile* The Emergence of Anion-π CatalysisAcc. Chem. Res. 2018, 51, 2255-2263

12.      Xiang Zhang, Le Liu,Lopez-Andarias, Chao Wang, Naomi Sakai, Stefan Matile* Anion-π Catalysis: Focus on Nonadjacent stereocenters. Helv. Chim. Acta 2018, 101, e1700288. (co-first author)

11.      Le Liu, Yoann Cotelle, Anna-Bea Bornhof, Celine Besnard, Naomi Sakai and Stefan Matile* Anion-π Catalysis of Diels-Alder Reactions. Angew. Chem. Int. Ed. 2017, 56, 13066-13069 (Hot Paper)

10.      Le Liu, Yoann Cotelle, Vincent Lebrun, Naomi Sakai, Thomas R. Ward and Stefan Matile* Anion-π Catalysis: Bicyclic Products with Four Contiguous Stereogenic Centers from Otherwise Elusive Diastereospecific Domino Reactions on π-Acidic Surfaces. Chem. Sci. 2017, 8, 3770-3774.

9.      Le Liu and Stefan MatieAnion-π transaminase mimics. Supramol. Chem. 201729, 702-706.

8.       Le Liu; Yuann, Cotelle; Alyssa-Jennifer, Avestro; Naomi, Sakai and Stefan Matile* Asymmetric Anion-π Catalysis of Iminium/Nitroaldol Cascades to Form Cyclohexane Rings with Five Stereogenic Centers Directly on π-Acidic Surfaces. J. Am. Chem. Soc. 2016138, 7876-7879.

7.        Le Liu; Tonghuan, Zhang; Yun-Fang, Yang; Daisy Zhang-Negrerie; Xinhao Zhang, Yunfei Du;* Yun-Dong Wu* and Kang Zhao* Metal-Free Synthesis of 3Arylquinolin-2-ones from Acrylic Amides via a Highly Regioselective 1,2-Aryl Migration: An Experimental and Computational Study. J. Org. Chem. 2016, 81, 4058-4065.

6.        Le Liu; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* Hypervalent Iodine Mediated C-C Double Bond Activation:A Cascade Access to a-Keto Diacetates from Readily Available Cinnamic Acids. Synthesis, 2015, 47, 2924-2930 (Invited Paper).

5.     Le Liu; Liang, Du; Daisy Zhang-Negrerie and Yunfei Du* NIS-mediated intramolecular oxidative a-functionalization of tertiary amines: transition metal-free synthesis of 1,2-dihydro-(4H)-3,1-benzoxazin-4-one derivatives. RSC Adv. 2015, 5, 29774-29781.

4.     Le Liu; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* PhICl2 and Wet DMF: An Efficient System for Regioselective Chloroformyloxylation/a-hlorination of Alkenes/a,baturated Compounds. Org. Lett. 2014, 16, 436-439.

3.     Le Liu; Liang, Du; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* Metal-Free Tandem Oxidative Aryl Migration and C−C Bond Cleavage: Synthesis of a-Ketoamides and Esters from Acrylic Derivatives. Org. Lett. 2014, 16, 5772-5775.

2.     Le Liu; Hang, Lu; Hong, Wang; Chao, Yang; Xiang, Zhang; Daisy Zhang-Negrerie; Yunfei Du* and Kang Zhao* PhI(OCOCF3)2Mediated C-C Bond Formation Concomitant with a 1,2-Aryl Shift in a Metal-Free Synthesis of 3Arylquinolin-2-ones. Org. Lett. 2013, 15, 2906-2909.

1.     Le Liu; Yanfeng, Fan; Qiaoqiao, He; Yun, Zhang; Daisy Zhang-Negrerie; Jianhui, Huang,* Yunfei Du* and Kang Zhao Synthesis of Functionalized Fluorescent Indenes from Electron-Rich α-Aryl Ketonitriles. J. Org. Chem. 2012, 77, 3997-4004.




1.   杜云飞,刘乐,贺巧巧,赵康, 1,3-二腈基2-取代-1H-茚类衍生物及其制备方法,发明专利,授权时间:2014122,专利号:CN102617400A