基本信息

 

 

       孙瑞芳,西安交通大学医学部病理学系副教授,硕士生导师。

       2002-2007年就读于西安交通大学,获医学/法学双学士学位。2013年于西安交通大学获医学博士学位。2011-2012年在美国哈佛大学医学院公派留学。2013年起在西安交通大学医学部病理学系工作。

       工作至今一直承担医学基础课程《病理学》的教学工作,参编教材三本。

       主要从事肿瘤分子病理、基因表达调控、环境对消化道疾病的作用及分子机制研究工作。主持国家自然科学基金1项、陕西省自然科学基金1项、国家博士后基金2项、陕西省博士后基金1项、西安交通大学科研基金2项。在《New England Journal of Medicine》、《Journal of the National Cancer Institute》、《Cell Death & Disease》、《The FASEB Journal》、《Acta Biomaterialia》、《Materials Today Bio》等学术期刊发表学术论文30余篇。获陕西高等学校科学技术研究优秀成果奖特等奖1项。

教育经历

2002.09-2007.07,西安交通大学,医学/法学双学士

2007.09-2013.06,西安交通大学,医学博士(直博)

工作经历

2011.10-2012.10  哈佛大学医学院,留学

研究领域

1、肿瘤分子病理机制,

2、基因表达调控机制,

3、环境对消化道疾病的作用及分子机制。

科研项目

没有找到条目。
项目编号 项目名称 项目来源 起讫时间 承担角色 项目类别
81802788 TRIM24-FOXI1-AE2轴调控细胞内酸碱平衡影响胃癌细胞增殖的研究 国家自然科学基金项目 2019-01~2021-12 负责人 纵向项目
2018JM7028 FOXI1调控BRD7抑制胃癌细胞侵袭迁移的作用及机制 陕西省自然科学基金项目 2018-01~2020-12 负责人 横向项目
2019T120918 FOXI1异常甲基化通过CAMTA1影响胃癌迁移侵袭 中国博士后科学基金会 2017-09~2019-07 负责人 横向项目
2018BSHEDZZ91 FOXI1通过BRD7抑制胃癌干细胞自我更新及迁移侵袭的机制研究 陕西省博士后基金会 2017-09~2019-07 负责人 横向项目
2017M620458 FOXI1调控胃癌干细胞自我更新及侵袭转移的分子机制 中国中国博士后科学基金会 2017-09~2019-07 负责人 横向项目

论文期刊

没有找到条目。
论文标题 作者 发表/完成日期 期刊名称
FOCAD/miR-491-5p, downregulated by EGR1, function as tumor suppressor by inhibiting the proliferation and migration of gastric cancer cells Ruifang Sun#, Zhigang Liu#*, Yun Lv#, Yanqi Yang#, Yang Yang, Yu Xiang, Qiuyu Jiang, Chang'an Zhao, Moqi Lv, Jian Zhang, Juan Zhang, Caixia Ding, Dangxia Zhou* 2022-07-03 Progress in Biophysics and Molecular Biology
FLG Is a Potential Biomarker of Prognosis and Immunotherapy in Skin Cutaneous Melanoma Shaobo Wu#, Yuxia Liang, Qijuan Zang, Zixuan Xing, Pan Yin, Ruifang Sun*, Bingling Dai* 2022-05-14 Applied Bionics and Biomechanics
Effect of naturally derived surgical hemostatic materials on the proliferation of A549 human lung adenocarcinoma cells Wei-Dong Lü#*, Yi-Zhi Liu#, Yan-Qi Yang, Zhi-Gang Liu, Kun Zhao, Jian-Rong Lu, Guang-Yan Lei, Yi-Yu Wang, Lin Cai, Rui-Fang Sun* 2022-03-04 Mater Today Bio
FOXI1 inhibits gastric cancer cell proliferation by activating miR-590/ATF3 axis via integrating ChIP-seq and RNA-seq data Ruifang Sun#, Weidong Lü#, Zhigang Liu#, Yang Yang, Xiaofei Wang, Xinliang Zhao, Shufeng Fu, Wei Dai, Chen Huang*, Dongmei Diao* 2021-02-18 Progress in Biophysics and Molecular Biology
miR-491 inhibits BGC-823 cell migration via targeting HMGA2 Zhigang Liu#, Yun Lü#, Qiuyu Jiang, Yang Yang, Chengxue Dang*, Ruifang Sun* 2019-10-31 Int J Biol Markers
miR-22 and miR-214 targeting BCL9L inhibit proliferation, metastasis, and epithelial-mesenchymal transition by down-regulating Wnt signaling in colon cancer Ruifang Sun#, Zhigang Liu#, Lin Han#, Yang Yang, Fei Wu, Qiuyu Jiang, Huahua Zhang, Ruili Ma, Jiyu Miao, Kang He, Xiaofei Wang, Dangxia Zhou*, Chen Huang* 2019-01-30 The FASEB Journal
Photooxidatively crosslinked acellular tumor extracellular matrices as potential tumor engineering scaffolds Wei-Dong Lü#*, Rui-Fang Sun#, Ye-Rong Hu*, Jan-Rong Lu, Lu Gu, Zhi-Gang Liu, Guang-Yan Lei, Zhun Qiang, Lin Cai 2018-03-17 Acta Biomaterialia
Prognostic value of MRP, LRP and P-gp in patients with non-small cell lung cancer Zhigang Liu#, Ruifang Sun#, Juan Zhang, Caixia Ding, Gang Ma, Xinliang Zhao, Weidong Lü, Xiang Wang, Chengxue Dang* 2017-06-15 Int J Clin Exp Pathol
miR-491-5p, mediated by Foxi1, functions as a tumor suppressor by targeting Wnt3a/β-catenin signaling in the development of gastric cancer Ruifang Sun#, Zhigang Liu#, Dongdong Tong, Yang Yang, Bo Guo, Xiaofei Wang, Lingyu Zhao, Chen Huang* 2017-03-30 Cell Death and Disease
Prognostic value of neuroendocrine markers for predicting survival in patients with small cell lung cancer Ruifang Sun#*, Zhigang Liu#, Gang Ma, Caixia Ding, Weidong Lü, Juan Zhang, Xiang Wang, Dangxia Zhou 2016-06-15 Int J Clin Exp Pathol
Overexpression of stathmin is resistant to paclitaxel treatment in patients with non-small cell lung cancer Ruifang Sun#*, Zhigang Liu#, Lumin Wang, Weidong Lv, Jia Liu, Caixia Ding, Yong Yuan, Guangyan Lei, Changfu Xu 2015-04-18 Tumor Biol
Associations of deregulation of mir-365 and its target mRNA TTF-1 and survival in patients with NSCLC Ruifang Sun#*, Zhigang Liu#, Gang Ma, Weidong Lv, Xinliang Zhao, Guangyan Lei, Changfu Xu 2015-03-15 Int J Clin Exp Pathol
Aspirin and Colorectal Cancer Incidence and Mortality by CTNNB1 Expression: A Molecular Pathological Epidemiology (MPE) Study Sun R#, Nishihara R, Qian ZR, Chan AT, and Ogino S* 2013-03-11 Cancer Epidemiol Biomarkers Prev
Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival Xiaoyun Liao#, Paul Lochhead#, Reiko Nishihara#, Teppei Morikawa, Aya Kuchiba, Mai Yamauchi, Yu Imamura, Zhi Rong Qian, Yoshifumi Baba, Kaori Shima, Ruifang Sun, Katsuhiko Nosho, Jeffrey A Meyerhardt, Edward Giovannucci, Charles S Fuchs*, et al 2012-10-25 N Engl J Med
Prospective Study of Family History and colorectal cancer risk by tumor line-1 Methylation_level Shuji Ogino#, Reiko Nishihara#, Paul Lochhead#, Yu Imamura, Aya Kuchiba, Teppei Morikawa, Mai Yamauchi, Xiaoyun Liao, Zhi Rong Qian, Ruifang Sun, Kaori Sato, Gregory J Kirkner, Molin Wang, Donna Spiegelman, Jeffrey A Meyerhardt, Eva S Schernhammer, et al 2012-10-18 J Natl Cancer Inst
The -938A/A genotype of BCL2 gene is associated with esophageal cancer Zhigang Liu#, Ruifang Sun#, Weidong Lü, Chengxue Dang, Yangrong Song, Cheng Wang, Xi Zhang, Le Han, Hao Cheng, Wei Gao, Jia Liu, Guangyan Lei* 2011-12-21 Med Oncol
Genetic polymorphisms of 10 X-STR among four ethnic populations in northwest of China Ruifang Sun#, Yongsheng Zhu, Feng Zhu, Wenjian Kuang, Jiali Feng, Zhao Tian, Zhaoqin Chai, Yao Liu, Shengbin Li* 2011-08-02 Mol Biol Rep
Polymorphisms of three new microsatellite sites of the dystrophin gene R F Sun#, Y S Zhu, J L Feng, Z Tian, W J Kuang, Y Liu, H B Zhang*, S B Li* 2011-04-26 Genet Mol Res
The G-712A polymorphism of brain-derived neurotrophic factor is associated with major depression but not schizophrenia R F Sun#, Y S Zhu, W J Kuang, Y Liu, S B Li* 2010-12-01 Neurosci Lett

联系方式

电子邮箱: ruifang_sun@xjtu.edu.cn

 

个人主页https://gr.xjtu.edu.cn/web/ruifang_sun

 

联系地址: 西安市雁塔西路76号/中国西部科技创新港21号楼