科研成果

期刊文章Selected Publications

[17] Z. Ya#, S. Guo#, Y. Li#, M. Zhu, L. Zhang, Y. Zong*, and M. Wan*, Focused acoustic vortex-mediated sonochemotherapy for the amplification of immunogenic cell death combined with checkpoint blockade to potentiate cancer immunotherapy, Biomaterials, 301: 122278 (2023).(并列第一作者)

[16] S. Guo*, Z. Ya, P. Wu, Y. Li, S. Lu, L. Zhang, and M. Wan*, Enhanced thermal ablation via an acoustic vortex with a large focal region, Journal of Applied Physics, 134: 044901 (2023).

[15] S. Lu*, R. Su, C. Wan, S. Guo, and M. Wan*, Passive acoustic mapping with absolute time-of-flight information and delay-multiply-sum beamforming, Medical Physics,  50:2323-2335 (2023).

[14] S. Guo*, Z. Ya, P. Wu, and M.Wan*, A review on acoustic vortices: Generation, characterization, applications and perspectives, Journal of Applied Physics, 132: 210701 (2022).

[13] S. Guo, Z. Ya, P. Wu, L. Zhang, and M. Wan*, Enhanced sonothrombolysis induced by high intensity focused acoustic vortex, Ultrasound in Med. Biol. 48(9):1907-1917 (2022).

[12] P. Wu, Z. Ya, Y. Li, M. Zhu, L. Zhang, Y. Zong,* S. Guo,* and M. Wan*, Focused acoustic vortex-regulated composite nanodroplets combined with checkpoint blockade for high-performance tumor synergistic therapy, ACS Appl. Mater. Interfaces 14: 30466-30479 (2022).(共同通讯)

[11] P. Wu, M. Zhu, Y. Li, Z. Ya, Y. Yang, Y. Yuan, W. Dong,S. Guo, S. Lu, L. Zhang, Y. Zong, and M. Wan, Cascade-amplifying synergistic therapy for intracranial glioma via endogenous reactive oxygen species-triggered “All-in-One” nanoplatform, Advanced Functional Materials, 2021, 2105786.

[10] S. Guo, X. Wang, X. Guo, Z. Ya, P. Wu, A. Bouakaz, and M. Wan, Decreased clot debris size and increased efficiency of acoustic vortex assisted high intensity focused ultrasound thrombolysis, Journal of Applied Physics, 128: 094901 (2020).

[9] S. Guo, X. Guo, X. Wang, X. Du, P. Wu, A. Bouakaz and M. Wan, Manipulation of nanodroplets via a nonuniform focused acoustic vortex, Physical Review Applied, 13: 034009 (2020).

[8]S. Guo, X. Guo, X. Wang, D. Zhou, X. Du, M. Han, Y. Zong, M. Wan, Reduced clot debris size in sonothrombolysis assisted with phase-change nanodroplets, Ultrasonics Sonochemistry, 54: 183-191 (2019).

[7] S. Xu, Nan Chang, R. Wang, X. Liu, S. Guo, S. Wang, Y. Zong, M. Wan, Acoustic droplet vaporization and inertial cavitation thresholds and efficiencies of nanodroplets emulsions inside the focused region using a dual-frequency ring focused ultrasound. Ultrasonics Sonochemistry, 48, 532-537 (2018).

[6] M. Han, N. Wang, S. Guo, N. Chang, S. Lu, M. Wan, Nakagami-m parametric imaging for characterization of thermal coagulation and cavitation erosion induced by HIFU. Ultrasonics Sonochemistry, 45: 78-85 (2018).

[5] L. Zhao, Y. Feng, A. Shi, L. Zhang, S. Guo, M. Wan, Neuroprotective effect of low-intensity pulsed ultrasound against mpp+-induced neurotoxicity in pc12 cells: involvement of k2p channels and stretch-activated ion channels. Ultrasound in Medicine & Biology, 43(9): 1986-1999 (2017).

[4] S. Guo, A. Shi, S. Xu, X. Du, X. Wang, Y. Zong, A. Bouakaz, and M. Wan, Lowering of acoustic droplet vaporization threshold via aggregation, Applied Physics Letters, 111, 254102 (2017).

[3] S. Guo, X. Du, X. Wang, S. Lu, A. Shi, S. Xu, A. Bouakaz, and M. Wan, Reduced clot debris size using standing waves formed via high intensity focused ultrasound, Applied Physics Letters, 111: 123701 (2017)

[2] A. Shi, P. Huang, S. Guo, L. Zhao, Y. Jia, Y. Zong, M. Wan, Precise spatial control of cavitation erosion in a vessel phantom by using an ultrasonic standing wave. Ultrasonics Sonochemistry, 31: 163-172 (2016).

[1] T. Ding, H. Hu, C. Bai, S. Guo, M. Yang, S. Wang, M. Wan, Spatial-temporal three-dimensional ultrasound plane-by-plane active cavitation mapping for high-intensity focused ultrasound in free field and pulsatile flow. Ultrasonics, 69: 166-181(2016).

 

会议 Symposium

[9] S. Guo, Y. Li, Z. Ya, Y. Feng, and M. Wan*, Efficient concentration of cells in Petri dishes using a miniaturized acoustic vortex, IEEE International Ultrasonics Symposium (IUS), Montreal, Quebec, Canada, 2023, September 3-8.

[8] S. Guo, Y. Li, Z. Ya, P. Wu, M. Wan*, Enhancement of ultrasound-mediated blood-brain barrier opening by aggregating microbubbles via an acoustic vortex, IEEE International Ultrasonics Symposium (IUS), Venice, Italy, 2022, October 10-13.

[7] S. Guo, Z. Ya, P. Wu, M. Wan*, Enhancement of sonothrombolysis efficiency using high intensity focused acoustic vortex, IEEE International Ultrasonics Symposium (IUS), XI’an, China, 2021, September 11-16

[6] S. Guo, Z. Ya, P. Wu, Y. Li, M. Wan, Efficient thermal ablation of high intensity focused acoustic vortex, IEEE International Ultrasonics Symposium (IUS), Xi’an, China, 2021, September 11-16.

[5] S. Guo, X. Guo, Z. Ya, P. Wu, M. Wan, Reduced length/width ratio of thermal ablation induced by high intensity focused acoustic vortex, IEEE International Ultrasonics Symposium (IUS), Las Vegas, US, 2020, September 8-11.

[4] S. Guo, Z. Ya, X. Guo, P. Wu, M. Wan, Dexterous and precise adjustment of the focal region location in acoustic vortices, IEEE International Ultrasonics Symposium (IUS), Las Vegas, US, 2020, September 8-11.

[3] S. Guo, X. Wang, X. Guo, X. Du, P. Wu, A. Bouakaz, M. Wan, Reduced debris size and improved efficiency in acoustic vortex-assisted sonothrombolysis, IEEE International Ultrasonics Symposium (IUS), Glasgow, UK, 2019, October 6-9.

[2] S. Guo, X. Guo, X. Wang, X. Du, P. Wu, A. Bouakaz, M. Wan, Lowering of acoustic droplet vaporization threshold via a non-uniform focused vortex, IEEE International Ultrasonics Symposium (IUS), Glasgow, UK, 2019, October 6-9.

[1] S. Guo, X. Du, X. Wang, X. Guo, M. Wan, Generation of medium-high intensity focused acoustic vortex and its application in sonothrombolysis, IEEE International Ultrasonics Symposium (IUS), Kobe, Japan, 2018, October 22-25.

专著Monographs

[1] 徐姗姗,郭世放,刘晓东,万明习, “11超声空化与声致液滴相变”[M]. 计算生物医学超声学科学出版社, 2018

 

专利Patents

[5]万明习,郭世放,郭叙言,王昕,杜轩, 基于空间非均匀聚焦涡旋声场的相变纳米液滴调控方法.中国,发明专利,ZL201910663023.3

[4]万明习,郭世放,郭叙言,王昕,牙振, 一种低强度聚焦涡旋声场辅助的超声精细高效溶栓系统.中国,发明专利,ZL201911054021.0

[3] 万明习,郭世放,杜轩,王昕,郭叙言,一种空间聚焦涡旋声场的产生装置及方法.中国,发明专利,ZL201811006029.5

[2] 万明习丁婷胡虹杨淼郭世放 微秒分辨空化时空分布的三维空化定量成像方法中国,发明专利,CN104535645A

[1] M. Wan, T. Ding, H. Hu, M. Yang, S. Guo, THREE-DIMENSIONAL CAVITATION QUANTITATIVE IMAGING METHOD FOR MICROSECOND-RESOLUTION CAVITATION SPATIAL-TEMPORAL DISTRIBUTION, United States Patent, US10,332,250 B2.