分子识别与荧光传感在化学工程与材料、生物医学等交叉学科领域有着广阔的应用前景，尤其在医学精准医疗、疾病早期诊断、生物环境检测等方向受到越来越多的关注。

Organic synthesis to prepare small molecules fluorescence probes that can be utilized to understand and exploit biological/environmental systems, mainly in the fluorescent detection of reactive oxygen and nitrogen species, carbohydrates, self-propagating cascades for the detection of nerve agents and combination of small molecular fluorescent probe with supporting materials, such as graphene oxide, porous silicon material, hydrogels. We proposed the strategy of selective detection of peroxynitrile over other reactive oxygen species by using boron-nitrogen interaction. Based on the traditional indicator displacement assay (IDA), we reported a new protocol for the selective detection of targets, referring to reaction-based indicator displacement assay (RIA). We also developed new approaches to auto-Inductive cascades for the optical sensing of fluoride/thiol: application in the ultratrace detection of phosphoryl nerve agents. And we explored and summarized the true mechanism by using nitrogen-boron interaction based fluorescent probe in the detection of saccharides. 

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