学术论文-SCI

[1] Xinxin Zhang, Zhaowei Xue, Shangjun Zhu, Yuting Guo, Yan Zhang, Jianwei Dou, Jiye Zhang, Yoichiro Ito, Zengjun Guo. Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI/HSP70/NF-κB anti-inflammatory axis. Phytomedicine, 2022, 153991.

[2] Zhaowei Xue, Zhen Cao, Ming Jin, Xinxin Zhang*Xinrui Wang, Jianwei Dou, Yuhong Zhu, Yoichiro Ito, Zengjun Guo. New bitter substances from medicine food homologous Dioscorea zingiberensis yam and their potential functions. Food & Function, 2021, 12(18), 8314-8325.

[3] Xinxin Zhang, Xingbin Wang, Zhaowei Xue, Guanqun Zhan, Yoichiro Ito, Zengjun Guo. Prevention properties on cerebral ischemia reperfusion of medicine food homologous Dioscorea yam-derived diosgenin based on mediation of potential targets. Food Chemistry, 2021, 345: 128672-128684.

[4] Muhammad Khurm, Xingbin Wang, Hui Zhang, Sajid Nawaz Hussain, Muhammad Naeem Qaisar, Khezar Hayat, Fatima Saqib, Xinxin Zhang*, Guanqun Zhan, Zengjun Guo. The genus Cassia L.: Ethnopharmacological and phytochemical overview. Phytotherapy Research, 2020, 1-50.

[5] Xinxin Zhang, Xingbin Wang, Muhammad Khurm, Guanqun Zhan, Hui Zhang, Yoichiro Ito, Zengjun Guo. Alterations of brain quantitative proteomics profiling revealed the molecular mechanisms of diosgenin against cerebral ischemia reperfusion effects. Journal of Proteome Research, 2020, 19(3): 1154-1168.

[6] Xinxin Zhang, Ming Jin, Nigatu Tadesse, Guanqun Zhan, Hui Zhang, Jun Dang, Sicen Wang, Zengjun Guo, Yoichiro Ito. Methods to treat the industrial wastewater in diosgenin enterprises produced from Diosorea zingiberensis C. H. Wright. Journal of Cleaner Production. 2018, 186: 34-44.

[7] Xinxin Zhang, Guanqun Zhan, Ming Jin, Hui Zhang, Jun Dang, Yan Zhang, Zengjun Guo, Yoichiro Ito. Botany, traditional use, phytochemistry, pharmacology, quality control, and authentication of Radix Gentianae Macrophyllae-A traditional medicine: A review. Phytomedicine, 2018, 46: 142-163.

[8] Xinxin Zhang, Ming Jin, Nigatu Tadesse, Jun Dang, Tao Zhou, Hui Zhang, Sicen Wang, Zengjun Guo, Yoichiro Ito. Dioscorea zingiberensis C. H. Wright: An overview on its Traditional Use, Phytochemistry, Pharmacology, Clinical Applications, Quality Control, and Toxicity. Journal of Ethnopharmacology, 2018, 220: 283-293.

[9] Xinxin Zhang, Ming Jin, Nigatu Tadesse, Liang Xian, Hui Zhang, Sicen Wang, Jun Dang, Yan Zhang, Zengjun Guo, Yoichiro Ito. Safety investigation on total steroid saponins extracts from Dioscorea zingiberensis C.H. Wright: Sub-acute and chronic toxicity studies on dogs. Regulatory Toxicology and Pharmacology, 2017, 91: 58-67.

[10] Xinxin Zhang, Dandan Li, Xuanji Xue, Yan Zhang, Jie Zhang, Chen Huang, Zengjun Guo, Nigatu Tadesse. First total synthesis of a novel amide alkaloid derived from Aconitum taipeicum and its anticancer activity. Natural Product Research, 2017, (9): 1-5.

[11] Xinxin Zhang, Xuanji Xue, Jing Zhao, Zengjun Guo, Yoichiro Ito, Wenji Sun. Quantitative determination of gracillin by HPLC-MS/MS after oral administration and its application to a pharmacokinetic study. Steroids, 2016, 113: 78-86.

[12]Xinxin Zhang, Xuanji Xue, Liang Xian, Zengjun Guo, Yoichiro Ito, Wenji Sun. Potential neuroprotection of protodioscin against cerebral

ischemia-reperfusion injury in rats through intervening inflammation and apoptosis. Steroids, 2016, 113: 52-63.

[13]Xinxin Zhang, Zengjun Guo, Jing Li, Yoichiro Ito, Wenji Sun. A new quantitation method of protodioscin by HPLC-ESI-MS/MS in rat plasma and its application to the pharmacokinetic study. Steroids, 2016, 106: 62-69.

[14]Xinxin Zhang, Xuanji Xue, Jing Zhao, Chunxiang Qian, Zengjun Guo, Yoichiro Ito, Wenji Sun. Diosgenin attenuates the brain injury induced by transient focal cerebral ischemia-reperfusion in rats. Steroids, 2016, 113: 103-112.

[15]Xinxin Zhang, Jing Li, Yoichiro Ito, Wenji Sun. Simultaneous quantification of five steroid saponins from Dioscorea zingiberensis C. H. Wright in rat plasma by HPLC-MS/MS and its application to the pharmacokinetic studies. Steroids, 2015, 93, 16-24.

[16]Xinxin Zhang, Jinru Liang, Jianli Liu, Ye Zhao, Juan Gao, Wenji Sun, Yoichiro Ito. Quality control and identification of steroid saponins from Dioscorea zingiberensis C.H.Wright by fingerprint with HPLC-ELSD and HPLC-ESI-Quadrupole/Time-of-fight tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2014, 91: 46-59.

[17]Xinxin Zhang, Yoichiro Ito, Jinru Liang, Jianli Liu, Jiao He, Wenji Sun. Therapeutic effects of total steroid saponin extracts from the rhizome of Dioscorea zingiberensis C.H.Wright in Freund’s complete adjuvant induced arthritis in rats. International Immunopharmacology, 2014, 23, 407-416.

[18]Xinxin Zhang, Lin Chen, Xuan Dang, Jianli Liu, Yoichiro Ito, Wenji Sun. Neuroprotective effects of total steroid saponins on cerebral ischemia injuries in an animal model of focal ischemia/reperfusion. Planta Medica, 2014, 80: 637-644.

[19]Xinxin Zhang, Lin Chen, Jianli Liu, Yoichiro Ito, Jiao He, Wenji Sun. Neuroprotection of total steroid saponins from Dioscorea zingiberensis against transient focal cerebral ischemia-reperfusion injury in rats via its anti-inflammatory and anti-apoptotic effects. Planta Medica, 2014, 80, 1597-1604.

[20]Xinxin Zhang, Yoichiro Ito, Jinru Liang, Qi Su, Yongmin Zhang, Jianli Liu, Wenji Sun. Preparative isolation and purification of five steroid saponins from Dioscorea zingiberensis C. H. Wright by counter-current chromatography coupled with evaporative light scattering detector. Journal of Pharmaceutical and Biomedical Analysis, 2013, 84: 117-123.

[21]Xinxin Zhang, Jianli Liu, Wenji Sun, Yoichiro Ito. Comparative Studies on Performance of CCC and Preparative RP-HPLC in Separation and Purification of Steroid Saponins from Dioscorea Zingiberensis C. H. Wright. Journal of Steroids & Hormonal Science, 2015, 6(1): 1-9.

学术论文-中文

[1] 金明, 仙靓, 孙丽娜, 石硕, 张卉, 张新新*, 郭增军. 盾叶薯蓣中甾体皂苷的分离与结构鉴定. 西北药学杂志, 2017, (04): 395-399.

[2] 张新新, 杨洋, 刘建利, 王燕, 孙文基. 地奥心血康胶囊中甾体皂苷类成分的HPLC-ELSD指纹图谱. 中国医药工业杂志, 2015, 46(1): 65-67.

[3] 张新新, 梁晋如, 赵文娜, 郝群峰, 孙文基, 王燕. 气相色谱法测定瑞克卫瑞消毒液中桂皮醛和丁香酚的含量. 西北大学学报(自然科学版), 2015, 45(2): 257-260.

[4] 张新新, 杨洋, 刘胜家, 孙文基. 藏木香中土木香内酯和异土木香内酯的制备. 中国医药工业杂志, 2014, 45(2): 116-119.

[5] 张新新, 梁晋如, 赵晔, 孙文基. 盾叶薯蓣药材甾体总皂苷成分HPLC-ELSD指纹图谱的研究. 中国中药杂志, 2013, 38(19): 15-20.

[6] 张新新, 梁晋如, 苏琪, 谢人明, 孙文基. HPLC-ELSD法同时测定盾叶薯蓣根茎中5个皂苷的含量. 药物分析杂志, 2013, 33(7): 1235-1238.

[7] 张新新, 贾娜, 孙琛, 赵文娜, 孙文基. 大叶秦艽花与麻花秦艽花抗炎镇痛作用的研究. 西北药学杂志, 2012, 27(4): 341-343.

[8] 张新新, 陈国权, 刘向辉, 王利娜, 巩江, 倪士峰. 人中白药学研究概况. 宁夏农林科技, 2012, 53(06): 129-130.

[9] 张新新, 许丹, 梁晋如, 孙文基. HPLC法测定忍冬藤及金银花中马钱苷的含量. 西北大学学报(自然科学版), 2012, 42 (1): 38-42.

[10]张新新, 黄亮辉, 叶根德, 王燕. 气相色谱外标法测定川贝枇杷糖浆中薄荷脑的含量. 药物分析杂志, 2011, 31(5): 947-949.

出版物

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出版物 作者 出版日期 出版社
新药发现与筛选 郭增军 2017-01-01 西安交通大学出版社