基本信息

 

西安交通大学医学部药理学系 教授

西安交通大学基础医学院心血管研究所副所长

联系方式

地址: 西安交通大学医学部药理学系

         西安市 雁塔区 雁塔西路76号   

邮编: 710061

电话: 029-82655165

Email: zzh@mail.xjtu.edu.cn

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Basic Informatiom

     Dr. Zhenghang Zhao, a professor of Pharmacology and Doctoral Supervisor, once served as the director of Department of Pharmacology, serves as the deputy director of Cardiovascular Institute Sciences. From September 2004 to March 2007, he was a postdoctoral fellow at the Department of Biomedical Sciences, University of Warwick, UK, and from January 2009 to November 2010, at the Department of Cell Biology and Molecular Sciences, Rutgers University, New Jersey School of Medicine, USA. He is a reviewer of the National Natural Science Foundation of China, Chinese Postdoctoral Fund, Doctoral/Master's degree thesis of Academic Degree Center of Ministry of Education.

   His research team focuses on Cardiovascular Pharmacology and Physiology, including the Ionchannelpathy, Electrophysiology of Arrhythmias, Ca2+ handling, mitochondrial and lysosomal function and relevant diseases in the heart and other tissue, with particular emphasis on the mechanisms underlying cardiac hypertrophy, myocardial infraction, and cardiac remodeling/hear failure in experimental and natural animal models. The following techniques are used in the studies: patch clamp, single cell Ca2+ imaging and contraction, and intact tissue or whole-heart voltage, and molecular biology techniques including genomics, proteomics, metabolomics, transgenic animals etc., as well as the evaluation and development of new drug pharmacodynamics and toxicology and drug metabolism kinetics.

   He has got more than 15 scientific research projects supported by the National Natural Science Foundation of China (8 projects), the Ministry of Education of China, International cooperation, Science and Technology Bureau of Shaanxi Province, and more than 40 new drug research and development projects. He has published more than 50 academic papers in international academic journals such as Cardiovascular Res, JMCC, and FASEB J, Am J Physiol-Heart Circ Physiol, J Physiol (London)Brit J PharmacolActa Physiol(Oxf)Antioxidants, Food and Function, etc.

     

The specific research topics are:

1. Mechanism and intervention of cardiac hypertrophy, cardiac remodeling and heart failure.

2. Ionic and cellular mechanisms for arrhythmias induced by a variety of pathological stress.

3. Basic study of Oncocardiology: the mechanism and prevention of cardiotoxicity during the treatment of malignant diseases.

4. The role of macrophages and their crosstalk with cardiomyocytes in cardiac ischemia and remodeling.

5. The mechanisms and drug targets of arterial stenosis and remodeling,pulmonary arterial hypertension

工作经历

  2019.4~                      西安交通大学基础医学院心血管研究所副所长

  2015.4~2019.4           西安交通大学基础医学院药理学系主任

  2012.12~                    西安交大医学部药理学系 教授/博导

  2009.12010.11        美国UMDNJ-New Jersey Medical School, 博士后研究

  2004.92007.3         英国Warwick大学生物学系, 博士后研究

 

 
 

 

社会兼职

学术兼职 兼职审稿
陕西省药理学会副理事长 Journal of Pharmaceutical Analysis
陕西省药理学会心血管专业委员会副主委 Toxicology and Applied Pharmacology
中国药理学会表观遗传药理学专业委员会常务委员 Pharmacological Research
中国药理学会心血管药理专业委员会委员 Journal of Cardiovascular Pharmacology
陕西省生理科学会常务理事 Frontiers in Physiology
国家自然科学基金评审专家 Life Sciences
西安市药械安全监测评价专家 Molecular and Cellular Biochemistry (MCBI)
教育部学位中心博士、硕士学位论文通讯评议专家

西安交通大学学报(医学版