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个人信息
Personal Information
  • 教师姓名: 补亚忠
  • 电子邮箱:
  • 所在单位: 基础医学院
  • 办公地点:
  • 性别: 男
  • 联系方式:
  • 学位: 博士
  • 职称: 研究员
  • 毕业院校: 中国人民大学、中国科学院大学
  • 博士生导师: 是
  • 硕士生导师: 是
  • 学科: 生物学

论文成果

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2026

[41] M. Su, H. Hou, Z. Qu, R. Wu, Y. Bu*, Z. Weng*, B. Du*, A Controllable and Separable Nanozyme-Based Platform for Enhanced Signal-Off Colorimetric Biosensing, Advanced Sustainable Systems 10(4) (2026) e70467.

[40]B. Zhu, X. Yang, H. Ren, S.M. Saldaña, W. Duan, B. Zhang, Q. Liu, L. Feng, Y. Zhu, Y. Chen, L. Dang, J. Li, B. Du *, H. Wang *, Y. Bu *, From passive to bioactive: Engineering a smart Band-Aid for complex wound care, Chem. Eng. J. 537 (2026) 176314.

[39] Y. Zhu, M. Zhang, L. Feng, Y. Chen, Y. Ren, Y. Zhao, X. Wu, X. Zou, A. Zhang, B. Zhu*, Y. Bu*, Q. Li*, Y. Luo*, Injectable gallic acid-engineered zwitterionic hydrogel for preventing postoperative adhesions in thyroid surgery through modulating oxidative stress and inflammation, Materials Today Bio 36 (2026) 102706.

[38] A. Zhang, W. Jia, W. Wei, Z. Qu, M. Su, Y. Bu*, B. Du*, L. Xiong*, Development of a PMOF/GOx-based colorimetric test strip for non-invasive glucose detection in tear samples, Microchem. J. 222 (2026) 117235.

[37] L. Luo, X. Wu, Y. Zhu, Y. Chen, B. Zhu, Y. Gong, R. Bohara, D. He, Y. Bu*, L. Yan*, A sponge scaffold with microchannels to accelerate bone repair, Materials & Design 263 (2026) 115598.

2025

[36] B. Zhu, Y. Chen, X. Yang, Y. Zhu, Y. Zhao, Q. Liu, B. Wang, S. Martin-Saldaña, Y. Wang, W. Duan, L. Feng, B. Du, J. Li, Y. Bu*, Succinamide ester-containing adhesive hydrogels with controllable degradation for biomedical applications, Cell Biomaterials 1(10) (2025) 100176.

[35] Y. Zhao, W. Duan, B. Zhu, Y. Chen, Y. Zhu, S. Martin-Saldaña, Z. Xiao, X. Liu, L. Feng, Y. Ren, Y. Gong, F. Huo, J. Li, Y. Bu*, B. Du*, L. Zhang*, Nanozyme-Engineered Hyaluronic Acid Adhesives Loading Platelet-Rich Plasma for Multilayered Osteoarthritis Treatment with Pain-Relief Effect, Adv. Funct. Mater. 35 (2025) 2418660.

[34] B. Wang, B. Zhu, Y. Liu, B. Ren, Y. Chen, L. Feng, S. Martin-Saldana, B. An, Y. Gong, Y. Ren, J. Li, D. Huang*, B. Du*, J. Liu*, Y. Bu*, Fast Recoverable Shape Memory Cryogels Engineered with Surfactant-Stabilized Bubbles and Vermiculite for Non-Compressible Hemostasis, Adv. Funct. Mater. 35 (2025) 2414340.

[33] Z. Sun, J. Zhou, L. Sheng, M. Zou, D. He, F. Xiong, D. Xie, B. Chen, Y. Bu*, Z. Huang*, Microfluidic engineering of microgels: fabrication methods, structural design, assembly strategies, and biomedical applications, Acta Biomaterialia 207 (2025) 142-173.

[32] Q. Liu, B. Zhu, H. Yang, C. Liu, Y. Chen, X. Wu, W. Duan, L. Feng, B. Wang, L. Shao, J. Gao, Y. Bu*, H. Liu*, K. Mao*, J. Liu*, Engineering injectable bone/bioadhesive grafts delivery system with self-healing properties for bone regeneration, Bioactive Materials 54 (2025) 47-70.

[31] W. Jia, B. Zhu, A. Zhang, H. Hou, Z. Qu, Y. Bu*, L. Liu*, B. Du*, Hydrophilic Shape-Memory Nanozyme Aerogel for the Development of a Reusable and Signal-Amplified Sensor, Adv. Funct. Mater. 35 (2025) 2418910.

[30] W. Jia, B. Zhu, D. Xiang, B. Zhang, Z. Qu, Z. Hua, L. Xiong, Y. Bu*, B. Du*, J. Jia*, Peroxidase nanozyme-incorporated sponge: A smartphone-enabled dual-mode visual sensing platform for trace uric acid detection via a shape-memory effect-driven signal amplification strategy, Biosens. Bioelectron. 283 (2025) 117541.

[29] T. Huo, B. Zhu, X. Shan, J. Song, Z. Wang, J. Zhou, X. Zhang, Y. Bai, C. Liu, Y. Zhao, N. Mei, Y. Bu*, J. Zhang*, G. Li*, Allicin amplifies disulfidptosis during GOx catalyzing glucose-starvation for cancer therapy via simultaneous antimicrobial and antitumor intervention, Chem. Eng. J. 505 (2025) 159871.

[28] S. Hu, W. Duan, X. Jin, C. Li, B. Zhu, Y. Chen, Y. Zhu, P. Cao, Z. Dong, L. Feng, J. Yu, X. Sun, Z.Y.H. Mahmood, Y. Bu*, B. Du, J. Zheng*, In Situ Forming Injectable Gelatin-Based Antibacterial Bioadhesives for Preventing Postoperative Leakage and Abdominal Adhesions, Macromolecular Bioscience 25 (2025) 2400372.

[27] H. Hou, W. Jia, A. Zhang, M. Su, Y. Bu*, L. Liu*, B. Du*, Unveiling Generally-ignored Co-substrate Effect of Catalase-inherent Peroxidase Mimic for Self-verifiable Detection of High-concentration Hydrogen Peroxide, Small Methods 9 (2025) e2400847.

[26] L. Feng, B. Zhu, Z. Liu, R. Jia, Y. Chen, Y. Ren, Y. Zhu, R. Bohara, M. Bao, W. Duan, X. Wu, Z. Xiao, T. Wang, Y. Dou, B. Du, J. Li*, Y. Zhu*, Y. Bu*, A Versatile Approach to Synergistically Combine Physical Barriers and Bioactive Agents for Intrauterine Adhesion Prevention, Adv. Funct. Mater. (2025) e14793.

[25] L. Dang, A. Zhang, J. Li, J. Cao, X. Rong, M. Su, B. Du, Y. Bu*, ATP-enhanced platinum nanoparticle's peroxidase activity in alkaline environment for simplifying alkaline phosphatase detection, Sensing and Bio-Sensing Research 48 (2025) 100798.

2024

[24] B. Zhang, Y. Gong, L. Liu, H. Hou, X. Gao, Y. Bu*, B. Du*, L. Yan*, Hydrogel-Embedded Platinum–Ruthenium Alloy Peroxidase Mimic as a Visual Sensor for “Signal-on” Alkaline Phosphatase Detection, ACS Applied Nano Materials 7 (2024) 11248-11257.

[23] Q. Yang, J. Liao, L. Feng, S. Wang, Z. Zhao, J. Wang*, Y. Bu*, J. Zhuang, D.W. Zhang*, One-step Construction of Multiplexed Enzymatic Biosensors Using Light-addressable Electrochemistry on a Single Silicon Photoelectrode, Biosens. Bioelectron. 253 (2024) 116194.

[22] L. Luo, Y. Gong, L. Yan*, Y. Bu*, Sponge as Scaffolds in Bone and Cartilage Tissue Engineering, Chem. Res. Chin. Univ. 40 (2024) 786–797.

[21] Y. Gong, B. Zhu, Y. Chen, F. Li, W. Duan, S. Martin-Saldaña, R. Yang, X. Gao, B. Zhang, L. Luo, Z. Xiao, B. Du*, L. Yan*, Y. Bu*, Organism-Inspired Antioxidant Bioadhesive with Strong Sealing Ability to Prevent Epidural Adhesion, ACS Nano 18(32) (2024) 21411-21432.

[20] Y. Gong, C. Li, B. Zhu, F. Li, L. Feng, Y. Zhao, Q. Liu, B. Wang, L. Luo, B. Du, Y. Bu*, D. Hao*, L. Yan*, Engineering injectable bioadhesives with sealing and anti-fouling properties for postoperative anti-adhesion, Chem. Eng. J. 500 (2024) 156747.

2023

[19] W. Duan, X. Jin, Y. Zhao, S. Martin-Saldaña, S. Li, L. Qiao, L. Shao, B. Zhu, S. Hu, F. Li, L. Feng, Y. Ma, B. Du*, L. Zhang*, Y. Bu*, Engineering injectable hyaluronic acid-based adhesive hydrogels with anchored PRP to pattern the micro-environment to accelerate diabetic wound healing, Carbohydr. Polym. 337 (2024) 122146.

[18] Y. Zhu, L. Zhang, W. Duan, S. Martin-Saldaña, C. Li, H. Yu, L. Feng, X. Zhang, B. Du, G. Li, X. Zheng*, Y. Bu*, Succinic Ester-Based Shape Memory Gelatin Sponge for Noncompressible Hemorrhage without Hindering Tissue Regeneration, Adv. Healthcare Mater. 12(5) (2023) 2202122.

[17] L. Feng, L. Wang, Y. Ma, W. Duan, S. Martin-Saldaña, Y. Zhu, X. Zhang, B. Zhu, C. Li, S. Hu, M. Bao, T. Wang, Y. Zhu*, F. Yang*, Y. Bu*, Engineering Self-Healing Adhesive Hydrogels with Antioxidant Properties for Intrauterine Adhesion Prevention, Bioact. Mater. 27 (2023) 82-97.

[16] W.L. Duan, L.N. Zhang, R. Bohara, S. Martin-Saldaña, F. Yang, Y.Y. Zhao, Y. Xie*, Y.Z. Bu*, A. Pandit*, Adhesive Hydrogels in Osteoarthritis: From Design to Application, Mil Med Res 10(1) (2023) 4.

2022

[15] P. Wang, Y. Zhu, L. Feng, Y. Wang, Y. Bu*, Rapidly Self-Deactivating and Injectable Succinyl Ester-Based Bioadhesives for Postoperative Antiadhesion, ACS Appl. Mater. Interfaces 14(1) (2022) 373-382.

[14] C. Li, W. Duan, Y. Zhu, G. Li, M. Gao, Z. Weng*, Y. Zhu*, Y. Bu*, Cohesion Design-Led Tough Sealants with Controllably Dissolvable Properties, ACS Appl. Mater. Interfaces 14(30) (2022) 34415-34426.

[13] Y. Bu, W. Zhang, S. Martin-Saldaña, A.M. Alsharabasy, M. Da Costa, L. Feng, Z. Zhang, X. Ge, C. Li, S. Lu, A. Pandit*, Plant-Inspired Multifunctional Bioadhesives with Self-Healing Adhesion Strength to Promote Wound Healing, Advanced Materials Interfaces 10 (2022) 2201599.

[12] Y. Bu, G. Sun, D. Huang, F. Yang, Editorial: Interfacial strategies to manipulate tissue interactions for wound healing, Front Bioeng Biotechnol 10 (2022) 995721.

[11] Y. Bu, A. Pandit*, Cohesion mechanisms for bioadhesives, Bioact. Mater. 13 (2022) 105-118.

2021

[10] W. Duan, X. Bian, Y. Bu*, Applications of Bioadhesives: A Mini Review, Front. bioeng. biotechnol. 9(702) (2021) 716035.

Before 2021

[9] F. Sun#, Y. Bu#, Y. Chen, F. Yang, J. Yu, D. Wu, An Injectable and Instant Self-Healing Medical Adhesive for Wound Sealing, ACS Appl. Mater. Interfaces 12(8) (2020) 9132-9140.

[8] A.H.J. Gowda, Y. Bu*, O. Kudina, K.V. Krishna, R.A. Bohara, D. Eglin, A. Pandit*, Design of tunable gelatin-dopamine based bioadhesives, Int. J. Biol. Macromol. 164 (2020) 1384-1391.

[7] Y. Bu, X. Wang, L. Li, X. Hu, D. Tan, Z. Li, M. Lai, X. Qiu, F. Sun, H. Wang, F. Yang*, D. Wu*, J. Guo*, Lithium Loaded Octa-Poly(Ethylene Glycol) Based Adhesive Facilitates Axon Regeneration and Reconnection of Transected Peripheral Nerves, Adv. Healthcare Mater. 9(13) (2020) 2000268.

[6] Y. Bu#, L. Zhang#, G. Sun, F. Sun, J. Liu, F. Yang, P. Tang*, D. Wu*, Tetra-PEG Based Hydrogel Sealants for In Vivo Visceral Hemostasis, Adv. Mater. 31(28) (2019) 1901580.

[5] Y. Bu, J. Ma, J. Bei, S. Wang, Surface Modification of Aliphatic Polyester to Enhance Biocompatibility, Front. Bioeng. Biotechnol. 7(98) (2019).

[4] Y. Bu#, G. Sun#, L. Zhang, J. Liu, F. Yang*, P. Tang*, D. Wu*, POSS-modified PEG adhesives for wound closure, Chin. J. Polym. Sci. 35(10) (2017) 1231-1242.

[3] Y. Bu, H. Shen, F. Yang, Y. Yang, X. Wang, D. Wu*, Construction of Tough, in Situ Forming Double-Network Hydrogels with Good Biocompatibility, ACS Appl. Mater. Interfaces 9(3) (2017) 2205-2212.

[2] D. Li#, Y. Bu#, L. Zhang, X. Wang, Y. Yang, Y. Zhuang, F. Yang, H. Shen, D. Wu*, Facile Construction of pH- and Redox-Responsive Micelles from a Biodegradable Poly(beta-hydroxyl amine) for Drug Delivery, Biomacromolecules 17(1) (2016) 291-300.

[1] Y. Bu#, L. Zhang#, J. Liu, L. Zhang, T. Li, H. Shen, X. Wang, F. Yang*, P. Tang*, D. Wu*, Synthesis and Properties of Hemostatic and Bacteria-Responsive in Situ Hydrogels for Emergency Treatment in Critical Situations, ACS Appl. Mater. Interfaces 8(20) (2016) 12674-12683.