李海
  • 教授
  • 博士生导师
  • 硕士生导师
  • 性别:男
  • 学历:博士研究生毕业
  • 学位:博士
  • 所在单位:基础医学院
  • 电子邮箱:
  • 办公地点:(科研)西安交通大学转化医学研究院
    陕西省西安市西咸新区沣西新城
    中国西部科技创新港泓仁楼

    (教学)西安交通大学基础医学院
    陕西省西安市雁塔西路76号微免楼
  • 联系方式:
  • 学科:基础医学
  • 学科:基础医学
Publications
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1. Feng S#, Cui L#, Zhu Y#, Cheng Y, Diao D, Li X, Duan H, Zhang H, Liu X, Pan Q, Ji F, Zhang Y*, Ou C*, Li H*. Pan-cancer oncolytic virotherapy through disruption of tumor cell mitochondrial dynamics. Molecular Therapy‌. 2026; 34;11: S1525-0016(26)00708-2.

2. Li X#, Liang Y#, Zhang Y#, Fa B#, Liu Z, Cui L, Xi M, Feng S, Xu L, Liu X, Xiao Z*, Liu S*, Li H*. Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference. npj Vaccines. 2025; 18;10(1):99.

3. Li X, Liang Y, Zhang Y, Liu Z, Cui L, Xi M, Feng S, Liu X, Zhu Y, Liu S*, Li H*. Dynamic Immune Response Landscapes of Avian Peripheral Blood Post-Vaccination Against Infectious Bronchitis Virus Infection. Vaccines. 2025;13(2):146.

4. Xuefeng Li, Xiaoxiao Liu, Lu Cui, Zheyi Liu, Yu Zhang*, Hai Li*. How to Break through the Bottlenecks of in Ovo Vaccination in Poultry Farming. Vaccines. 2024; 12(1):48. 

5. Liang Y#, Ma Y#, Zhang Y, Chen Z, Wang Z, Li X, Cui L, Xu L, Liu S*, Li H*. Single-Cell Analysis of the In Vivo Dynamics of Host Circulating Immune Cells Highlights the Importance of Myeloid Cells in Avian Flaviviral Infection. Journal of Immunology. 2021; 207(11): 2878-91.

6. Qiao Y#, Wang Z#, Han Z, Shao Y, Ma Y, Liang Y, Chen Z, Wu H, Cui L, Zhang Y, Liu S*, Li H*. Global exploration of the metabolic requirements of gallid alphaherpesvirus 1. PLoS Pathogens. 2020; 16(8): e1008815.

7. Ma Y, Liang Y, Wang N, Cui L, Chen Z, Wu H, Zhu C, Wang Z, Liu S*, Li H*. Avian Flavivirus Infection of Monocytes/Macrophages by Extensive Subversion of Host Antiviral Innate Immune Responses. Journal of Virology. 2019; 93(22): e00978-19.

8. Li H#, Gao Q#, Shao Y, Sun B, Wang F, Qiao Y, Wang N, Liu S*. Gallid Herpesvirus 1 Intitates Apoptosis in Uninfected Cells through Paracrine Repression of p53. Journal of Virology. 2018; 92(18): e00529-18.

9. Li H#, Wang F#, Han Z, Gao Q, Li H, Shao Y, Sun N, Liu S*. Genome-wide gene expression analysis identifies the proto-oncogene tyrosine-protein kinase Src as a crucial virulence determinant of the infectious laryngotracheitis virus in chicken cells. Journal of Virology. 2016; 90(1): 9-21.

10. Li H, Zhang Y, Ströse A, Tedesco D, Gurova K, Selivanova G*. Integrated high throughput analysis identifies Sp1 as a crucial determinant of p53-mediated apoptosis. Cell Death & Differentiation. 2014; 21(9): 1493-502.

11. Shi Y, Nikulenkov F, Zawacka-Pankau J, Li H, Gabdoulline R, Xu J, Eriksson S, Hedström E, Issaeva N, Kel A, Arnér E, Selivanova G*. ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis. Cell Death & Differentiation. 2014;21(4):612-23.

12. Li H, Lakshmikanth T, Carbone E, Selivanova G*. A novel facet of tumor suppression by p53: induction of tumor immunogenicity. Oncoimmunology. 2012;1(4):541-543.

13. Nikulenkov F, Spinnler C, Li H, Tonelli C, Shi Y, Turunen M, Kivioja T, Ignatiev I, Kel A, Taipale J, Selivanova G*. Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death & Differentiation. 2012;19(12):1992-2002.

14. Li H, Lakshmikanth T, Garofalo C, Enge M, Spinnler C, Anichini A, Szekely L, Kärre K, Carbone E*, Selivanova G*. Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2. Cell Cycle. 2011;10(19):3346-58.

15. Spinnler C, Hedström E, Li H, de Lange J, Nikulenkov F, Teunisse AF, Verlaan-de Vries M, Grinkevich V, Jochemsen AG, Selivanova G*. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX. Cell Death & Differentiation. 2011;18(11):1736-45.