严谨、自由

招收材料学、生物学及相关专业硕士、博士研究生。

 
张兰，女，1982.1生，博士，西安交通大学材料学院教授。
  2004、2006年武汉理工大学材料学专业获学士、硕士学位，
    2010.1西安交通大学材料学专业获博士学位。

陕西省杰出青年基金获得者，主持省部级以上项目8项，其中国家自然基金项目4项，累计到款400余万元。

研究方向：钛、锆、锌、铝等金属材料表面改性，设计功能化纳米结构陶瓷、高分子涂层，评价涂层表面性质对其耐磨耐蚀及生物学性能的影响。

2010.1-2013.12 材料学院讲师

2014.1-2018.12 材料学院副教授

2018.8-2019.7  麻省大学阿姆斯特分校，访问学者

2019.1-        材料学院教授    

1997.7-2000.7 江苏省泰州中学
2000.9-2004.7 武汉理工大学 材料学学士
2004.9-2006.7 武汉理工大学 材料学硕士
2006.9-2010.1 西安交通大学 材料学博士

lan.zhang@mail.xjtu.edu.cn

金属材料表面生物医用改性、纳米生物功能材料

论文发表：

     2026 年

1. Huihui Xie, Jing Zhang, Kang Liu, Junzhe Tang, Chenming Zhang, Yitian Lu, Yixuan Shi, Dehao Wang, Yanhuai Li, Lan Zhang*. Electron-Rearranged CuMg@ZIF nanoplatform for pH-Responsive Sequential Therapy: From Infection Eradication to Neuroangiogenesis in Diabetic Wounds.Bioactive materials,  68 (2027) 579–597.

2.  Mengting Mao, Jun Chen, Lin Zhao, Qinyan Li, Xinyue Liu, Yan Liu, Lan Zhang*. Regulating  Xenophagy and Phenotype of Macrophages by Selenium-Doped Nanoleaves on Zn-Based Implants for Infected Bone Integration.Bioactive materials,  63 (2026) 868–884

3.  Tiexin Ding,  Lan Zhang* Huihui Xie, Haozhe Guo, Shengda Wu, Jing Han, Yong Han*. Electroporation-Based Death of Bacteria on Assembled Piezoelectric Nanoenzyme-Tips for Implant Disinfection. Biomaterials, 2026331,124123

   2025年

4.  Huihui Xi,  Lan Zhang*, Tiexin Ding, Dehao Wang, Kang Liu, Dongsheng Li,  Yixuan Shi, Yitian Lu, Chengming Zhang, Shengda Wu, Shuilin Wu, Yong Han* A Bimetallic Catalyst Core-Shell Nanoplatform Enabling All-StageManagement of Infected Diabetic Wound Healing. Biomaterials327 (2026) 123771

5. Yang Xue,Lan Zhang*, Mengting Mao, Shengda Wu, Yingang Zhang, Yong Han*, “Sandwich” structured nanorods for timely antibiosis, immunoregulation and neuroangiogenesis to accelerate osteogenesis of Zn-based implants in diabetics,   Biomaterials 324 (2026) 123540 

6. Yang Xue#, Jin Shi#, Lan Zhang*, Xiaojing Zhang, Yingang Zhang, Yong Han*. One-Step Engineered Multifunctional Gauze: On-Demand Antibiosis, Accelerated Hemostasis, and Angiogenesis for Tissue Regeneration.International Journal of Biological Macromolecules 322 (2025) 146866 

7.  Mengting Mao, Lan Zhang*, Shengda Wu, Yong Han*. A core-shell structured VEGF-SiO2@ZnO nanorod array for enhancing osteogenesis of Zn-based implants, J. Mater. Chem. B, 2025,13, 9937-9953, 

8. Tiexin Ding, Lan Zhang*, Jun Chen , Dayan Ma, Jing Han, Yong Han*. “Thermal bubbles”: Photothermally triggered by a carbon monoxide nanocontainer for antibiosis and immune modulation therapy.Nano Today 63 (2025) 102758 

9. Yang Xue, Lan Zhang*, Jun Chen, Dayan Ma, Yingang Zhang, Yong Han*. An “all-in-one” therapeutic platform for programmed antibiosis, immunoregulation and neuroangiogenesis to accelerate diabetic wound healing. Biomaterials 321 (2025) 123293

10. Jing Zhang§, Yang Xue§, Lan Zhang*, Jun Chen, Dayan Ma, Yingang Zhang, Yong Han*. A Targeted Core-Shell ZIF-8/Au@Fe₃O₄ Platform with Multiple Antibacterial Pathways for Infected Skin Wound Regeneration. ACS Applied Materials & Interfaces  2025, 17, 20901-20918

11. Huihui Xie, Lan Zhang*, Jun Chen, Chen Wang, Yaxi Yan, Shulai Deng , Kang Liu, Dongsheng Li, Mo Yang, Jiachen Ren, Shuilin Wu, Yong Han*. A Dual-catalysis Mode for ROS Regulation to Accelerate Biointegration of Implants in Infected Diabetic Wound. Advanced Functional Materials2025, 35, 2423015

12. Huihui Xie§, Yijiao Wang§, Jiaqi Liu, Ruijun Wang, Dayan Ma*, Lan Zhang*. Engineering Hierarchically Grooved Structure for Enhancing Interfacial Solar Thermal Water Purification. ACS Appl. Mater. Interfaces 2025, 17, 15333-15346

    2024年

13. TiexinDing, Yan Li, Fuwei Liu, Jun Chen, Yicheng Chen, Liang Kong, Yong Han*, Lan Zhang*. Electron Spin Polarization Engineering in Ferromagnetic Bioheterojunction for Sonotherapy of Osteomyelitis.  Advanced Functional Materials. 2024,34 2401795.

    2023年

14. Mengting Mao, Jun Chen, Fuwei Liu, Liang Kong, Yong Han*, Lan Zhang*, Reduced corrosion of Zn alloy by HA nanorods for enhancing early bone regeneration, Biomaterials Science.20242024, 12, 1055

15.  Tiexin Ding, Fuwei Liu, He Xin, Yicheng Chen, Liang Kong, Jing Han, Dayan Ma, Yong Han,* Lan Zhang*. Pyro-Piezoelectric Effect of BaTiO₃ Bio-Nanocarrier for Osteomyelitis Therapy. Nano Today 54 (2024) 102069

16. Yang Xue, Lan Zhang*, Jianhong Zhou, Jun Chen, Yuwei Ma, and Yong Han*. Low-Dose Cu Ions Assisted by Mild Thermal Stimulus Inducing Bacterial Cuproptosis-Like Death for Antibiosis and Biointegration. Advanced Functional Materials 2024,34, 2308197. 

17. Yang Xue, Lan Zhang,* Fuwei Liu, Fang Dai, Liang Kong, Dayan Ma, and Yong Han* Alkaline “Nanoswords” Coordinate Ferroptosis-like Bacterial Death for Antibiosis and Osseointegration.ACS Nano 2023, 17, 3, 2711

18. Yang Xue, Lan Zhang*, Fuwei Liu, Liang Kong, Dayan Ma, Yong Han*.Fluoride releasing photothermal responsive TiO2 matrices for antibiosis, biosealing and bone regeneration. Journal of Controlled Release. 2023, 363, 657. 

19. Huihui Xie, Dayan Ma, Lan Zhang* A PPy modified Al₂O₃-mullite coating on Al alloys for anti-static electricity and corrosion resistance.Ceramics International, 2023,18885-18895

20. Tiexin Ding, Lan Zhang*, Jing Han, Jianhong Zhou, Yong Han* Photo-responded Antibacterial Therapy of Reinfection in Percutaneous Implants by Nanostructured Bio-heterojunction.Small,2023,19,22062625   

21.  Yang Xue, Lan Zhang*, Fuwei Liu, Liang Kong, and Yong Han* Immunomodulation and osteointegration of infected implants by ion-riched and hierarchical porous TiO2 matrix Nano Research.Nano Research,2023,16, 2905

    2022年

22.  Yang Xue, Lan Zhang*, Fuwei Liu, Yiwei Zhao, Jianhong Zhou, Yan Hou, Han Bao, Liang Kong, Fei Ma, Yong Han*. Surface Bandgap Engineering of Nanostructured Implants for Rapid Photothermal Ion Therapy of Bone Defects. Advanced Healthcare Materials，2022, 11，2200998

23.  Mao, Mengting; Zhu, Shengbo; Zhang, Lan*; Liu, Fuwei; Kong, Liang; Xue, Yang; Rotello, Vincent*; Han, Yong* An extracellular matrix-like surface for Zn alloy to enhance bone regeneration. ACS Applied Materials & Interfaces，2022，14，38，43955-43964

24. Huihui Xie，Lan Zhang* , Xinyu Zhang, Yong Han*.A hierarchically structured coating on 2A12-T4 aluminum alloy for anti-wear and corrosion, Corrosion Science207 (2022) 110598

25. Kai Li, Lan Zhang,* Jianhua Li, Yang Xue, Jianhong Zhou, and Yong Han*. pH-Responsive ECM Coating on Ti Implants for Antibiosis in Re-infected Models.ACS Appl. Bio Mater2022, 5, 1, 344–354.

     

    2021年

26.  Yang Xue, Jun Chen, Tiexin Ding, Mengting Mao, Shengbo Zhu, Jianhong Zhou, Lan Zhang*, Yong Han**. Building biointegration of Fe₂O₃–FeOOH coated titanium implant by regulating NIR irradiation in an infected model. Bioactive Materials, 8 (2022) 1-11

27. Lan Zhang†, Yang Xue†, Sanjana Gopalakrishnan, Kai Li, Yong Han*, Vincent M. Rotello*. Antimicrobial peptide-loaded  pectolite nanorods for enhancing wound-healing and biocidal activity of titanium implants.ACS Appl Mater Interfaces. 2021, 13, 28764−28773

28.  Huan-Ming Chen^&, Hao-Yu Huang^&, Yang Xue, Kai Li, Tie-Xin Ding, Xiao-Jun Cai,Jun Chen*, Lan Zhang*. mmobilization of pegylated AMP on hydroxyapatite nanorods for antibiosis. Rare Metals.  4.003  41, pages713–722 (2022)

29. Kai Li, Jun Chen, Yang Xue, Tiexin Ding, Shengbo Zhu, Mengting Mao, Lan Zhang*, Yong Han*. Polymer brush grafted antimicrobial peptide on hydroxyapatite nanorods  for highly effective antibacterial performance. Chemical Engineering Journal 423 (2021) 130133   

30. Yang Xue, Jun Chen, Lan Zhang*,Yong Han*, BSA-lysozyme coated NaCa2HSi3O9 nanorods on titanium for cytocompatibility and antibacterial activity.Journal of Materials Science & Technology 88 (2021) 240-249 

    2020年

31. Kai Li, Yang Xue, Lan Zhang* and Yong Han*,b-FeOOH/Fe-TiO₂ heterojunctions on Ti for bacterial inactivation under light irradiation and biosealing. Biomaterials Science, 2020,8, 6004-6016

32. Kai Li, Yang Xue, Ting Yan, Lan Zhang*, Yong Han*. Si substituted hydroxyapatite nanorods on Ti for percutaneous implants. Bioactive Materials, 2020, 5:116. 

33.  Lan Zhang^&, Sanjana Gopalakrishnan^&, Kai Li, Li-sheng Wang, Yong Han*, Vincent M. Rotello*. Fabrication of Collagen Films with Enhanced Mechanical and Enzymatic Stability through Thermal Treatment in Fluorous Media. ACS Appl Mater Interfaces, 2020, 12:6590.

34. Kai Li, Yang Xue, Jianhong Zhou, Jing Han, Lan Zhang*,Yong Han. Silanized NaCa2HSi3O9 nanorods with reduced pH increase on Ti for improving osteogenesis and angiogenesis in vitroJ Mater Chem B, 2020, 8:691.

    2019年：

35. Kai Li, Shiyu Liu, Yang Xue, Lan Zhang* Yong Han**.A superparamagnetic Fe3O4-TiO2 composite coating on titanium by micro-arc oxidation for percutaneous implants. Journal of Materials Chemistry B 2019,7, 5265-5276

36. Lan Zhang*, Ting Yan, Yang Xue, Yong Han*. Magnetic hydroxyapatite nanotubes on micro-arc oxidized titanium for drug loading. Mater.Res.Express 6(2019)095091

37. Kai Li, Fang Dai, Ting Yan, Yang Xue, Lan Zhang* and Yong Han.Magnetic Silicium Hydroxyapatite Nanorods for Enhancing Osteoblast Response in Vitro and Biointegration in Vivo. ACS Biomater. Sci. Eng. 2019, 5, 2208-2221

    2018年：

38.  Kai Li, Ting Yan, Yang Xue, Lijun Guo, Lan Zhang* and Yong Han*.Intrinsically ferromagnetic Fe-doped TiO₂ coatings on titanium for accelerating osteoblast response in vitro Journal of Materials Chemistry B,2018, 6, 5756

39. Lan Zhang, Jiaqi Guo, Ting Yan, Yong Han.Fibroblast responses and antibacterial activity of Cu and Zn co-doped TiO₂ for percutaneous implants. Applied Surface Science 2018, 434: 633  51  

*Corresponding author, e-mail: lan.zhang@mail.xjtu.edu.cn (Lan Zhang);

材料科学基础、材料腐蚀基础、生物医用材料

 研究生培养：

1.在读博士生                     入学时间                        研究方向  

      丁铁鑫                                         　  2020.9     　                   钛表面压电涂层的制备及表征

       毛梦婷                                                 2021.9                                  Zn表面功能涂层的制备及表征

  解惠惠                                    2023.9

2.在读硕士生                     入学时间                        研究方向  

　　  张晶                                                         2022.9

     郭昊哲                                     2023.9

3.毕业博士                   入学时间                           答辩时间                                         论文题目

        李凯                            2016.9                              2020.12.30                              钛表面磁性涂层构建及其骨整合响应与抗菌行为  

         薛阳                                          2020.3                                　     2023.2                                              钛表面多离子掺杂硅酸钙纳米纤维的制备及细胞组织响应

4.毕业硕士　　　　　　　　　                                  　时间  

  张晓静                                                                           2020.9 -2023.6   

   朱胜波                                                       　  201８.9 －2021.5                                 

　　燕婷                                      ２０１6.９－２０１9.５

       代芳　　　　　　　            ２０１５.９－２０１８.５

　　郭嘉祺                  　            ２０１４.９－２０１７.５

　　张娟　　　　　　　       　２０１４.９－２０１７.５

　　黄小燕　　　　　　       　２０１３.９－２０１６.５

　　高琴　　　　　　　       　２０１２.９－２０１５.５

　　王少波,孙巧飞　　　     　 ２０１０.９－２０１３.５

5.本科毕业设计                      　毕业时间  

       王琛、仵语盈                                                 2024.6

         郭昊哲                                                          2023.6

         张新宇、许可儿                                            2022.6

       朱雪冰、徐雯钰                                2019.6

        王涛, 林鸿昌                                    2018.6

        窦丹婷                                            2017.6

        朱少妤                                            2016.6

        汪娟，肖程彰                                  2015.6