教育经历：
(1) 2006-09 至 2009-12, 西安交通大学, 材料学, 博士
(2) 2004-09 至 2006-06, 武汉理工大学, 材料学, 硕士
(3) 2000-09 至 2004-06, 武汉理工大学, 材料学, 学士
科研与学术工作经历（博士后工作经历除外）：
(1) 2019-01 至 今, 西安交通大学, 材料学院, 教授
(2) 2014-01 至 2018-12, 西安交通大学, 材料学院, 副教授
(3) 2010-03 至 2013-12, 西安交通大学, 材料学院, 讲师
从事医用植入体表面生物多功涂层的设计、形成机制及性能研究。主持了国家自然科学基金项目4项以及陕西省杰出青年基金、陕西省自然基金重点项目等省部级以上项目 10项。在钛合金表面开发了氟沉降阳极氧化新技术、水热技术及氟介质热固化技术，研发了高结合强度TiO2纳米管、PDA/CuS/TiO2 纳米管状生物异质结、FeOOH/TiO2 异质结、Si/P 掺杂多孔 TiO2、BaTiO3纳米管等生物多功能涂层，并对这些涂层的结构特征、光/声响应效应、压电性能、细菌/细胞和组织响应进行了系统研究；近几年着重研究了超声波/近红外光激发下，涂层微观结构对适时抗菌及组织整合的作用。以第一作者或通讯作者在 Advanced Functional Materials、Biomaterials、ACS nano、Bioactive Materials、Small等期刊上发表 SCI 论文 50 余篇，授权国家发明专利8项，技术转让3项。
近期论文：
2026年
(1) Huihui Xie,......., Lan Zhang*. XXXXXXXXXX, submitted
(2) Mengting Mao, Jun Chen, Lin Zhao, Qinyan Li, Xinyue Liu, Yan Liu,Lan Zhang*. Regulating Xenophagy and Phenotype of Macrophages by Selenium-Doped Nanoleaves on Zn-Based Implants for Infected Bone Integration. Bioactive materials ,2026
(3) Tiexin Ding, Lan Zhang*, Huihui Xie, Haozhe Guo, Shengda Wu, Jing Han, Yong Han*. Electroporation-Based Death of Bacteria on Assembled Piezoelectric Nanoenzyme-Tips for Implant Disinfection. Biomaterials, 2026，331，124123.
2025年
(4) Huihui Xi, Lan Zhang*, Tiexin Ding, Dehao Wang, Kang Liu, Dongsheng Li, Yixuan Shi, Yitian Lu, Chengming Zhang, Shengda Wu, Shuilin Wu, Yong Han*. A Bimetallic Catalyst Core-Shell Nanoplatform Enabling All-Stage Management of Infected Diabetic Wound Healing.Biomaterials327 (2026) 123771，700
(5) Yang Xue, Lan Zhang*, Mengting Mao, Shengda Wu, Yingang Zhang, Yong Han*, “Sandwich” structured nanorods for timely antibiosis, immunoregulation and neuroangiogenesis to accelerate osteogenesis of Zn-based implants in diabetics, Biomaterials 324 (2026) 123540
(6) Yang Xue#, Jin Shi#, Lan Zhang*, Xiaojing Zhang, Yingang Zhang, Yong Han*. One-Step Engineered Multifunctional Gauze: On-Demand Antibiosis, Accelerated Hemostasis, and Angiogenesis for Tissue Regeneration. International Journal of Biological Macromolecules 322 (2025) 146866
(7) Mengting Mao, Lan Zhang*, Shengda Wu, Yong Han*. A core-shell structured VEGF-SiO2@ZnO nanorod array for enhancing osteogenesis of Zn-based implants, J. Mater. Chem. B, 2025,13, 9937-9953
(8) Tiexin Ding, Lan Zhang*, Jun Chen , Dayan Ma, Jing Han, Yong Han*. “Thermal bubbles”: Photothermally triggered by a carbon monoxide nanocontainer for antibiosis and immune modulation therapy. Nano Today 63 (2025) 102758
(9) Yang Xue, Lan Zhang*, Jun Chen, Dayan Ma, Yingang Zhang, Yong Han*. An “all-in-one” therapeutic platform for programmed antibiosis, immunoregulation and neuroangiogenesis to accelerate diabetic wound healing. Biomaterials 321 (2025) 123293
(10) Jing Zhang§, Yang Xue§, Lan Zhang*, Jun Chen, Dayan Ma, Yingang Zhang, Yong Han*. A Targeted Core-Shell ZIF-8/Au@Fe3O4 Platform with Multiple Antibacterial Pathways for Infected Skin Wound Regeneration. ACS Applied Materials & Interfaces 2025, 17, 20901-20918
(11) Huihui Xie, Lan Zhang*, Jun Chen, Chen Wang, Yaxi Yan, Shulai Deng , Kang Liu, Dongsheng Li, Mo Yang, Jiachen Ren, Shuilin Wu, Yong Han*. A Dual-catalysis Mode for ROS Regulation to Accelerate Biointegration of Implants in Infected Diabetic Wound. Advanced Functional Materials 2025, 35, 2423015
(12) Huihui Xie§, Yijiao Wang§, Jiaqi Liu, Ruijun Wang, Dayan Ma*, Lan Zhang*. Engineering Hierarchically Grooved Structure for Enhancing Interfacial Solar Thermal Water Purification. ACS Appl. Mater. Interfaces 2025, 17, 15333-15346
2024年
(13) TiexinDing, Yan Li, Fuwei Liu, Jun Chen, Yicheng Chen, Liang Kong, Yong Han*, Lan Zhang* Electron Spin Polarization Engineering in Ferromagnetic Bioheterojunction for Sonotherapy of Osteomyelitis. Advanced Functional Materials. 2024,34 2401795.
2023年
(14) Mengting Mao, Jun Chen, Fuwei Liu, Liang Kong, Yong Han*, Lan Zhang**, Reduced corrosion of Zn alloy by HA nanorods for enhancing early bone regeneration, Biomaterials Science. 2024, 12, 1055
(15) Tiexin Ding, Fuwei Liu, He Xin, Yicheng Chen, Liang Kong, Jing Han, Dayan Ma, Yong Han,* Lan Zhang*. Pyro-Piezoelectric Effect of BaTiO3 Bio-Nanocarrier for Osteomyelitis Therapy. Nano Today 54 (2024) 102069
(16) Yang Xue, Lan Zhang*, Jianhong Zhou, Jun Chen, Yuwei Ma, and Yong Han*. Low-Dose Cu Ions Assisted by Mild Thermal Stimulus Inducing Bacterial Cuproptosis-Like Death for Antibiosis and Biointegration.Advanced Functional Materials 2024,34, 2308197.
(17) Yang Xue, Lan Zhang*, Fuwei Liu, Fang Dai, Liang Kong, Dayan Ma, and Yong Han* Alkaline “Nanoswords” Coordinate Ferroptosis-like Bacterial Death for Antibiosis and Osseointegration. ACS Nano 2023, 17, 3, 2711
(18) Yang Xue, Lan Zhang*, Fuwei Liu, Liang Kong, Dayan Ma, Yong Han*. Fluoride releasing photothermal responsive TiO2 matrices for antibiosis, biosealing and bone regeneration.Journal of Controlled Release. 2023, 363, 657.
(19) Huihui Xie, Dayan Ma, Lan Zhang*. A PPy modified Al2O3-mullite coating on Al alloys for anti-static electricity and corrosion resistance. Ceramics International, 2023,18885-18895
(20) Tiexin Ding, Lan Zhang*, Jing Han, Jianhong Zhou, Yong Han* Photo-responded Antibacterial Therapy of Reinfection in Percutaneous Implants by Nanostructured Bio-heterojunction. Small，2023，19，22062625
(21) Yang Xue, Lan Zhang*, Fuwei Liu, Liang Kong, and Yong Han* Immunomodulation and osteointegration of infected implants by ion-riched and hierarchical porous TiO2 matrix Nano Research.Nano Research，2023,16, 2905
2022年
(22) Yang Xue, Lan Zhang*, Fuwei Liu, Yiwei Zhao, Jianhong Zhou, Yan Hou, Han Bao, Liang Kong, Fei Ma, Yong Han* Surface Bandgap Engineering of Nanostructured Implants for Rapid Photothermal Ion Therapy of Bone Defects. Advanced Healthcare Materials，2022, 11，2200998
(23) Mao, Mengting; Zhu, Shengbo; Lan Zhang*; Liu, Fuwei; Kong, Liang; Xue, Yang; Rotello, Vincent*; Han, Yong* An extracellular matrix-like surface for Zn alloy to enhance bone regeneration. ACS Applied Materials & Interfaces，2022，14，38，43955-43964
(24) Huihui Xie，Lan Zhang * , Xinyu Zhang, Yong Han**，A hierarchically structured coating on 2A12-T4 aluminum alloy for anti-wear and corrosion, Corrosion Science 207 (2022) 110598
(25) Kai Li, Lan Zhang*, Jianhua Li, Yang Xue, Jianhong Zhou, and ong Han*. pH-Responsive ECM Coating on Ti Implants for Antibiosis in Re-infected Models. ACS Appl. Bio Mater2022, 5, 1, 344–354.
2021年
(26) Yang Xue, Jun Chen, Tiexin Ding, Mengting Mao, Shengbo Zhu, Jianhong Zhou, Lan Zhang*, Yong Han**. Building biointegration of Fe2O3–FeOOH coated titanium implant by regulating NIR irradiation in an infected model. Bioactive Materials,8 (2022) 1-11
(27) Lan Zhang†, Yang Xue†, Sanjana Gopalakrishnan, Kai Li, Yong Han*, Vincent M. Rotello*. Antimicrobial peptide-loaded pectolite nanorods for enhancing wound-healing and biocidal activity of titanium implants. ACS Appl Mater Interfaces. 2021, 13, 28764−28773
(28) Huan-Ming Chen&, Hao-Yu Huang&, Yang Xue, Kai Li, Tie-Xin Ding, Xiao-Jun Cai, Jun Chen*, Lan Zhang*. Immobilization of pegylated AMP on hydroxyapatite nanorods for antibiosis. Rare Metals. 41, pages713–722 (2022)
(29) Kai Li, Jun Chen, Yang Xue, Tiexin Ding, Shengbo Zhu, Mengting Mao, Lan Zhang*, Yong Han*. Polymer brush grafted antimicrobial peptide on hydroxyapatite nanorods for highly effective antibacterial performance.Chemical Engineering Journal 423 (2021) 130133
(30) Yang Xue, Jun Chen, Lan Zhang*, Yong Han*, BSA-lysozyme coated NaCa2HSi3O9 nanorods on titanium for cytocompatibility and antibacterial activity.Journal of Materials Science & Technology88 (2021) 240-249 8.067
2020年
(31) Kai Li, Yang Xue, Lan Zhang* and Yong Han*,b-FeOOH/Fe-TiO2 heterojunctions on Ti for bacterial inactivation under light irradiation and biosealing.Biomaterials Science, 2020,8, 6004-6016
(32) Kai Li, Yang Xue, Ting Yan, L Lan Zhang*, Yong Han*. Si substituted hydroxyapatite nanorods on Ti for percutaneous implants. Bioactive Materials, 2020, 5:116.
(33) Lan Zhang&, Sanjana Gopalakrishnan&, Kai Li, Li-sheng Wang, Yong Han*, Vincent M. Rotello*. Fabrication of Collagen Films with Enhanced Mechanical and Enzymatic Stability through Thermal Treatment in Fluorous Media. ACS Appl Mater Interfaces, 2020, 12:6590.
(34) Kai Li, Yang Xue, Jianhong Zhou, Jing Han, Lan Zhang*, Yong Han*. Silanized NaCa2HSi3O9 nanorods with reduced pH increase on Ti for improving osteogenesis and angiogenesis in vitro. J Mater Chem B, 2020, 8:6
