• 校内登录
访问量:   最后更新时间:--

闫理贺

性别:男
职称:教授
博士生导师:是
硕士生导师:是
学历:硕博连读
学位:博士
所在单位:电子科学与工程学院
电子邮箱:
办公地点:西安交通大学创新港校区 弘理楼4-2105
学科:物理电子学
论文成果
当前位置: 中文主页 > 研究成果 > 论文成果

90. Qian Cui, Lihe Yan*, Ya’nan Shen, Jinhai Si, Xun Hou. Phase-regulated energy funneling and carrier relaxation dynamics in quasi-2D perovskites revealed by micro-area transient absorption spectroscopy. Journal of Chemical Physics, 2026, 164(1): 014708.

89. Huaxiong Gao, Tao Chen, Jin Huang, Yingjie Li, Lihe Yan*, Jinhai Si, Xun Hou. Influence of coating grating structures on femtosecond-laser inscription of fiber Bragg gratings. IEEE Photonics Technology Letters, 2026, 38(21): 1672-1675.

88. Zengyue Wang, Jianzheng Ma, Yanan Shen, Lihe Yan*, Hang Zhang, Jinhai Si, Hong Gao, Xun Hou. Layer-dependent ultrafast coherent acoustic phonon dynamics in GaTe driven by native oxidation. Ultrafast Science, 2026, 6: 0149.

87. Yubo Wu, Lihe Yan*, Kuanhong Cheng, Hang Zhang, Tao Chen, Jinhai Si, Xun Hou. Noise-robust phase unwrapping for smooth phase fields with physics-consistent constraints. Optics Express, 2026, 34(7): 13206-13221.

86.Lingxi Liu, Lihe Yan*, Jinhai Si, Xun Hou. StructuredLight-GNN: A graph neural network for end-to-end structured light 3D point cloud processing. Results in Optics, 2026, 22: 100943.

85. Ya’nan Shen, Zengyue Wang, Jinhai Si, Lihe Yan, Xun Hou. Unraveling the growth kinetics via in situ photoluminescence and carrier dynamics via transient absorption in CsPbBr3 nanocrystals. ACS Applied Nano Materials, 2026, 9(6): 3046-3056.

84. Qinjun Jian, Lihe Yan*, Jinhai Si, Xun Hou. Evolution and scintillation properties of partially coherent elliptical Airy beams in turbulent atmosphere. Physics Letters A, 2026, 584: 131620.

83. Jing Hu, Lihe Yan*, Jinhai Si, Xun Hou. Propagation dynamics and focusing characteristics of circular Airy Laguerre-Gaussian beams. Chaos, Solitons and Fractals, 2026, 207: 118004.

82. Ya’nan Shen, Lihe Yan*, Yifan Wang, Xiangbing Li, Yuxiang Zhao, Jinhai Si, Xun Hou. Influence of defect-state on the carrier dynamics in MAPbI3 polycrystalline films. Journal of Chemical Physics, 2025, 162(12): 124708.

81. Yanmin Xu, Lihe Yan*, Zengyue Wang, Ning Wang, Anyi Wang, Zhen Niu. Photoinduced carrier dynamics of spectral overlapping in self-assembled MoS2/graphene heterostructures. Optical Materials, 2025, 167: 117358.

80. Zengyue Wang, Ning Wang, Lihe Yan*, Yanmin Xu, Xiangbing Li, Yuxiang Zhao, Jinhai Si, Hong Gao, Xun Hou. Unveiling anomalous ultrafast carrier dynamics of strong spectral overlapping in few-layer MoS2. Journal of Physical Chemistry Letters, 2025, 16(13): 3287-3294.

79. Jing Hu, Lihe Yan*, Jinhai Si, Qinjun Jian, Xun Hou. Analysis of quadratic chirp effects on femtosecond pulse propagation in fused silica. Physics Letters A, 2025, 530: 130155.

78 .Zezhou Liang, Lihe Yan*, Xiaoming Li, Yufei Wang, Baofeng Zhao, Chao Gao, Jinhai Si, Hou Xun. Suppressing exciton-vibration coupling and reducing nonradiative energy loss in conjugated polymers through fluorine substitution in side chains. Energy and Environmental Materials, 2025, 8(3): e12856.

77. Jing Hu, Lihe Yan*, Zhoulin Ding, Jinhai Si, Qinjun Jian, Xun Hou. Generation of pulses with radially polarized circular Airy beam propagation characteristics via phase modulation. Optics and Laser Technology, 2025, 190: 113178.

76. Yanmin Xu, Lihe Yan*, Anyi Wang, Zhen Niu. Ultrafast carrier dynamics in 2D/0D graphene/MoS2/PbS quantum dots hybrid heterostructures. Optical Materials, 2025, 168: 117518.

75. Qinjun Jian, Jing Hu, Lihe Yan*, Jinhai Si, Xun Hou. Nonlinear dynamics and self-healing properties of elliptical Airy beams in Kerr media. Physical Review A, 2025, 112(2): 023507.

74. Jing Hu, Lihe Yan*, Jinhai Si, Xun Hou. Nonlinear optical forces of femtosecond polarized circular Airy Gaussian pulses on nanoparticles. Optics Letters, 2025, 50(16): 5149-5152.

73. Peipei Ma, Jinhai Si, Lihe Yan, Jiayi Wu, Jin Xu, Xun Hou. Influence of hot carrier cooling and band-filling effect on linewidth of perovskite microlasers. Advanced Optical Materials, 2024, 12(18): 2400189.

72. Chenxu Wang, Lihe Yan*, Jinhai Si, Ning Wang, Ting Li, Xun Hou. Exceptional stability against water, UV light, and heat for CsPbBr3@Pb-MOF composites. Small Methods, 2024, 8(12): 2400241.

71. Yanmin Xu, Lihe Yan*, Shaomin Fu, Yuanyuan Lv. Shell thickness influence on the carrier dynamics of InP/ZnS QDs. Chemical Physics Impact, 2024, 8: 100579.

70. Zezhou Liang, Lihe Yan*, Ning Wang, Jinhai Si, Shujuan Liu, Yufei Wang, Junfeng Tong, Jianfeng Li, Baofeng Zhao, Chao Gao, Xun Hou. Effect of 1-fluoro-2-iodobenzene solvent additive on the crystallization of donors and acceptors, and ultrafast carrier dynamics in polymer solar cells. Advanced Functional Materials, 2024, 34(13): 2310312.

69. Ben Liu, Jinhai Si, Lihe Yan, Yanan Shen, Xun Hou. Photoinduced carrier transfer dynamics in a monolayer MoS2/PbS quantum dots heterostructure. Optics Express, 2024, 32(11): 19458-19466.

68. Chenxu Wang, Jinhai Si, Lihe Yan, Ting Li, Xun Hou. Energy transfer enhanced photoluminescence of 2D/3D CsPbBr3 hybrid assemblies. Journal of Chemical Physics, 2024, 160(3): 034704.

67. Chenxu Wang, Lihe Yan*, Jinhai Si, Tianyu Huo, Xun Hou. Strongly luminescent and highly stable CsPbBr3/Cs4PbBr6 core/shell nanocrystals and their ultrafast carrier dynamics. Journal of Alloys and Compounds, 2023, 946: 169272.

66. Yueli Zhang, Lihe Yan*, Yuren Li, Jinhai Si, Wenjiang Tan, Xun Hou. Nonlinear optical limiting effect and charge transfer dynamics in a Fe-porphyrin metal-organic framework. Optical Materials Express, 2023, 13(2): 484-494.

65. Xiaodan Zhang, Lihe Yan*, Yanmin Xu, Jinhai Si, Xun Hou. Ultrafast carrier dynamic anisotropy of single crystal rhenium disulfide flake based on transient absorption spectroscopy. Optical Engineering, 2023, 62(4): 047102.

64. Ben Liu, Lihe Yan*, Jinhai Si, Yanan Shen, Xun Hou. Ultrafast photoinduced carrier transfer dynamics in monolayer MoS2/graphene heterostructure. Journal of Applied Physics, 2023, 134(21): 213101.

63. Peipei Ma, Lihe Yan*, Jinhai Si, Tianyu Huo, Zhenqiang Huang, Wenjiang Tan, Jin Xu, Xun Hou. Temporal-spatial-resolved lasing dynamics in customized solution grown perovskite single-crystal microcavities. Laser and Photonics Reviews, 2023, 17(12): 2300533.

62. Tianyu Huo, Lihe Yan*, Jinhai Si, Peipei Ma, Xun Hou. Ultrafast photoinduced carrier dynamics in single crystalline perovskite films. Journal of Materials Chemistry C, 2023, 11(11): 3736-3742.

61. Yanmin Xu, Lihe Yan*, Anyi Wang, Feng Tian, Xiaojun Huang, Jin Liu. Nonlinear optical performance and mechanism in MoS2/WS2 van der Waals heterostructures. Optical Materials, 2023, 143: 114213.

60. Tianyu Huo, Lihe Yan*, Jinhai Si, Peipei Ma, Yanan Shen, Xun Hou. Determination of the refractive-index change in the excited state based on transient absorption microscopy. Optics Letters, 2023, 48(24): 6561-6564.

59. Lihe Yan, Yaoyao Ma, Jinhai Si, Xun Hou. Optical limiting property and mechanism of 2D MXene Nb2CTx nanosheets. Optical Engineering, 2022, 61(2): 026108.

58. Yuren Li, Jinhai Si, Lihe Yan, Zhaolin Fan, Zezhou Liang, Xun Hou. Nonlinear optical limiting property of the carboxyl-functionalized Ti3C2 MXene nanosheets. Journal of Chemical Physics, 2022, 157(16): 164704.

57. Yuren Li, Lihe Yan*, Jinhai Si, Zezhou Liang, Wenbo Huang, Heping Ma, Xun Hou. Nonlinear optical limiting property and carrier dynamics in tin phthalocyanine porous organic frameworks. Journal of Chemical Physics, 2022, 156(5): 054702.

56. Lihe Yan, Zezhou Liang, Jinhai Si, Pingping Gong, Yufei Wang, Xingpeng Liu, Junfeng Tong, Jianfeng Li, Xun Hou. Ultrafast kinetics of chlorinated polymer donors: A faster excitonic dissociation path. ACS Applied Materials and Interfaces, 2022, 14(5): 6945-6957.

55. Xiaoyu Li, Lihe Yan*, Jinhai Si, Aizhao Pan, Yanmin Xu, Xun Hou. Tunable nonlinear absorption effect and carrier dynamics of perovskite quantum dots. Optical Materials Express, 2021, 11(2): 569-574.

54. Zezhou Liang, Lihe Yan*, Jinhai Si, Pingping Gong, Xiaoming Li, Deyu Liu, Jianfeng Li, Xun Hou. Rational design and characterization of symmetry-breaking organic semiconductors in polymer solar cells: A theory insight of the asymmetric advantage. Materials, 2021, 14(21): 6723.

53. Lihe Yan, Yanmin Xu, Jinhai Si, Yuren Li, Xun Hou. Enhanced optical nonlinearity of MXene Ti3C2Tx nanosheets decorated with silver nanoparticles. Optical Materials Express, 2021, 11(5): 1401-1409.

52. Vanthan Nguyen, Lihe Yan*, Na Zhao, Nguyen Van Canh, Nguyen Thi Nhat Hang, Phuoc Huu Le. Tuning photoluminescence of boron nitride quantum dots via surface functionalization by femtosecond laser ablation. Journal of Molecular Structure, 2021, 1244: 130922.

51. Yanmin Xu, Lihe Yan*, Jinhai Si, Ming Li, Yaoyao Ma, Jianlin Li, Xun Hou. Nonlinear absorption property and carrier dynamics in MoS2/graphene van der Waals heterostructures. Carbon, 2020, 165: 421-427.

50. Ming Li, Lihe Yan*, Jinhai Si, Xiaoyu Li, Jianlin Li, Xun Hou. Enhancement mechanism of the saturable absorption effect in reduced graphene oxide decorated with silver nanoparticles. Optical Materials Express, 2020, 10(4): 884-890.

49. Huanhuan Xu, Lihe Yan*, Jinhai Si, Xiaoyu Li, Yanmin Xu, Xun Hou. Influence of the photoluminescence property of carbon nanodots on the reduction of silver ions. Journal of Luminescence, 2020, 217: 116804.

48. Xiaoyu Li, Lihe Yan*, Jinhai Si, Yanmin Xu, Xun Hou. Control of the size and luminescence of carbon nanodots by adjusting ambient pressure in laser ablation process. Journal of Applied Physics, 2020, 127(8): 083102.

47. Jianlin Li, Lihe Yan*, Jinhai Si, Xun Hou. Study on optical limiting properties of new two-dimensional titanium carbide nanosheets. Hongwai yu Jiguang Gongcheng/Infrared and Laser Engineering, 2019, 48(11): 1103002.

46. Vanthan Nguyen, Na Zhao, Lihe Yan*, Peng Zhong, Van Canh Nguyen, Phuoc Huu Le. Double-pulse femtosecond laser ablation for synthesis of ultrasmall carbon nanodots. Materials Research Express, 2019, 7(1): 015606.

45. Xiaoyu Li, Lihe Yan*, Jinhai Si, Huanhuan Xu, Yanmin Xu. Tuning the photoluminescence property of carbon dots by ultraviolet light irradiation. RSC Advances, 2019, 9(22): 12732-12736.

44. Yanmin Xu, Lihe Yan*, Xiaoyu Li, Huanhuan Xu. Fabrication of transition metal dichalcogenides quantum dots based on femtosecond laser ablation. Scientific Reports, 2019, 9(1): 2931.

43. Yang Yu, Jinhai Si, Lihe Yan, Ming Li, Xun Hou. Enhanced nonlinear absorption and ultrafast carrier dynamics in graphene/gold nanoparticles nanocomposites. Carbon, 2019, 148: 72-79.

42. Yanmin Xu, Lihe Yan*, Jinhai Si, Na Zhao. Femtosecond laser-assisted fabrication of fluorescent boron nitride quantum dots. 2019 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2019, 2019: 7-10.

41. Yanmin Xu, Lihe Yan*, Mengmeng Yue, Yang Yu. Green hydrothermal synthesis of fluorescent carbon dots from glucose and taurine for Fe3+ and pH sensing. Nano, 2019, 14(1): 1950014.

40. Huanhuan Xu, Lihe Yan*, Jinhai Si, Yanmin Xu, Xun Hou. Femtosecond laser-assisted synthesis of ZnO nanoparticles in solvent with visible emission for temperature sensing. Nano, 2019, 14(5): 1950054.

39. Yang Yu, Lihe Yan*, Jinhai Si, Yanmin Xu, Xun Hou. Femtosecond laser assisted synthesis of gold nanorod and graphene hybrids and its photothermal property in the near-infrared region. Journal of Physics and Chemistry of Solids, 2019, 132: 116-120.

38. Vanthan Nguyen, Qi Dong, Lihe Yan*, Na Zhao, Phuoc Huu Le. Facile synthesis of photoluminescent MoS2 and WS2 quantum dots with strong surface-state emission. Journal of Luminescence, 2019, 214: 116554.

37. Xiaofang Wang, Lihe Yan*, Mengmeng Yue, Qi Dong. Pump polarization dependence of the optical Kerr gate with elliptically polarized probe light. Journal of Optics, 2018, 20(2): 025501.

36. Huanhuan Xu, Lihe Yan*, Yang Yu, Yanmin Xu. Facile synthesis of carbon-supported silver nanoparticles for optical limiting. Applied Surface Science, 2018, 457: 655-661.

35. Vanthan Nguyen, Lihe Yan*, Huanhuan Xu, Mengmeng Yue. One-step synthesis of multi-emission carbon nanodots for ratiometric temperature sensing. Applied Surface Science, 2018, 427: 1118-1123.

34. Mengmeng Yue, Jinhai Si, Lihe Yan, Yang Yu, Xun Hou. Enhanced nonlinear optical properties of reduced graphene oxide decorated with silver nanoparticles. Optical Materials Express, 2018, 8(3): 698-703.

33. Yang Yu, Lihe Yan*, Mengmeng Yue, Huanhuan Xu. Femtosecond laser-assisted synthesis of silver nanoparticles and reduced graphene oxide hybrid for optical limiting. Royal Society Open Science, 2018, 5(7): 171436.

32. Mengmeng Yue, Jinhai Si, Lihe Yan, Yang Yu, Xun Hou. Time- and frequency-resolved determination of ultrafast energy transfer in optical Kerr measurements. Applied Physics B: Lasers and Optics, 2017, 123(2): 53.

31. Huanhuan Xu, Lihe Yan*, Vanthan Nguyen, Yang Yu, Yanmin Xu. One-step synthesis of nitrogen-doped carbon nanodots for ratiometric pH sensing by femtosecond laser ablation method. Applied Surface Science, 2017, 414: 238-243.

30. Mengmeng Yue, Lihe Yan*, Yanmin Xu, Vanthan Nguyen, Tao Chen. Intense and collimated supercontinuum generation using microlens array. IEEE Photonics Technology Letters, 2017, 29(23): 2031-2034.

29. Yaobing Xiong, Lihe Yan*, Tao Chen. Nonlinear optical properties of cubic cuprous oxide with different sizes. Materials Letters, 2016, 172: 109-111.

28. Vanthan Nguyen, Jinhai Si, Lihe Yan, Xun Hou. Direct demonstration of photoluminescence originated from surface functional groups in carbon nanodots. Carbon, 2016, 108: 268-273.

27. Meng-Meng Yue, Lihe Yan*, Jin-Hai Si, Xun Hou. Influence of self-diffraction effect on femtosecond time-resolved single-shot optical Kerr measurements. Chinese Physics Letters, 2016, 33(4): 044202.

26. Vanthan Nguyen, Lihe Yan*, Jinhai Si, Xun Hou. Femtosecond laser-assisted synthesis of highly photoluminescent carbon nanodots for Fe3+ detection with high sensitivity and selectivity. Optical Materials Express, 2016, 6(2): 312-320.

25. Vanthan Nguyen, Lihe Yan*, Jinhai Si, Xun Hou. Femtosecond laser-induced size reduction of carbon nanodots in solution: Effect of laser fluence, spot size, and irradiation time. Journal of Applied Physics, 2015, 117(8): 084304.

24. Honglei Song, Lihe Yan*, Jinhai Si, Xun Hou. Optical limiter for ultrashort laser pulses based on ultrafast optical Kerr effect. Zhongguo Jiguang/Chinese Journal of Lasers, 2015, 42(2): 0217002.

23. Vanthan Nguyen, Jinhai Si, Lihe Yan, Xun Hou. Electron-hole recombination dynamics in carbon nanodots. Carbon, 2015, 95: 659-663.

22. Xuehui Sun, Lihe Yan*, Tao Chen, Yang Yu, Shigeki Matsuo. Effect of solvent surface tension on optical limiting properties of graphene dispersions. Laser Physics, 2015, 25(3): 035901.

21. Yaobing Xiong, Lihe Yan*, Jinhai Si, Wenhui Yi, Wen Ding, Wenjiang Tan, Xin Liu, Feng Chen, Xun Hou. Cascaded optical limiter with low activating and high damage thresholds using single-layer graphene and single-walled carbon nanotubes. Journal of Applied Physics, 2014, 115(8): 083111.

20. Yaobing Xiong, Jinhai Si, Lihe Yan, Honglei Song, Wenhui Yi, Xun Hou. The influence of nonlinear scattering light distributions on the optical limiting properties of carbon nanotubes. Laser Physics Letters, 2014, 11(11): 115904.

19. Yaobing Xiong, Lihe Yan*, Zhiguang Zhou, Wenhui Yi, Aoxiang Lin, Jinhai Si, Feng Chen, Xun Hou. Efficient optical Kerr gating property of fluorotellurite glass. Optik, 2014, 125(3): 1444-1447.

18. Pengchao He, Jinhai Si, Lihe Yan, Xin Liu, Xiaofang Wang, Feng Chen, Xun Hou. Ultrafast imaging of photoinduced nonlinear response in transparent materials using femtosecond optical polarigraphy technique. Optical Engineering, 2014, 53(5): 056101.

17. Xiaofang Wang, Lihe Yan*, Jinhai Si, Shigeki Matsuo, Huailiang Xu, Xun Hou. High-frame-rate observation of single femtosecond laser pulse propagation in fused silica using an echelon and optical polarigraphy technique. Applied Optics, 2014, 53(36): 8395-8399.

16. Xiaofang Wang, Jinhai Si, Lihe Yan, Pengchao He, Feng Chen, Xun Hou. Ultrafast single-shot imaging of femtosecond pulse propagation in transparent liquids using a supercontinuum and optical polarigraphy. Journal of Optics, 2014, 16(1): 015203.

15. Lihe Yan, Yaobing Xiong, Jinhai Si, Xuehui Sun, Wenhui Yi, Xun Hou. Optical limiting properties and mechanisms of single-layer graphene dispersions in heavy-atom solvents. Optics Express, 2014, 22(26): 31836-31841.

14. Lihe Yan, Xiaofang Wang, Jinhai Si, Pengchao He, Feng Chen, Jianhua Zou, Xun Hou. Multi-frame observation of a single femtosecond laser pulse propagation using an echelon and optical polarigraphy technique. IEEE Photonics Technology Letters, 2013, 25(19): 1879-1881.

13. Xiaofang Wang, Pengchao He, Lihe Yan*, Jinhai Si, Feng Chen, Xun Hou. Pump power dependence of the spatial gating properties of femtosecond optical Kerr effect measurements. Applied Physics B: Lasers and Optics, 2013, 112(2): 279-283.

12. Lihe Yan, Sen Jia, Jin-Hai Si, Shigeki Matsuo, Feng Chen, Xun Hou. Application of optical Kerr gate with SrTiO3 crystal in acquisition of gated spectra from a supercontinuum. Chinese Physics Letters, 2012, 29(7): 074207.

11. Lihe Yan, Sen Jia, Jinhai Si, Feng Chen, Wenhui Yi, Xun Hou. Influence of self-focusing effect on femtosecond collinear nondegenerate optical Kerr measurements. Optik, 2012, 123(8): 722-725.

10. Lihe Yan, Xiaofang Wang, Jinhai Si, Shigeki Matsuo, Tao Chen, Wenjiang Tan, Feng Chen, Xun Hou. Time-resolved single-shot imaging of femtosecond laser induced filaments using supercontinuum and optical polarigraphy. Applied Physics Letters, 2012, 100(11): 111107.

9. Shigeki Matsuo, Lihe Yan, Jinhai Si, Takuro Tomita, Shuichi Hashimoto. Reduction of pulse-to-pulse fluctuation in laser pulse energy using the optical Kerr effect. Optics Letters, 2012, 37(10): 1646-1648.

8. Sen Jia, Lihe Yan, Jinhai Si, Wenhui Yi, Feng Chen, Xun Hou. Third-order nonlinear optical properties of C60-doped bulk material and its application in ultrafast optical Kerr gate. Optical Engineering, 2011, 50(11): 119001.

7. Lihe Yan, Jinhai Si, Yaqi Yan, Feng Chen, Xun Hou. Pump power dependence of femtosecond two-color optical Kerr shutter measurements. Optics Express, 2011, 19(12): 11196-11201.

6. Sen Jia, Lihe Yan, Jinhai Si, Wenhui Yi, Feng Chen, Xun Hou. Self-focusing in two-color collinear optical Kerr measurements. Optics Communications, 2010, 283(21): 4346-4349.

5. Qing Yang, Lihe Yan, Juan-Juan Yue, Jin-Hai Si, Feng Chen, Tian-Xing Lin, Xun Hou, Guo-Dong Qian. Off-resonant third-order nonlinear optical properties of fullerene-doped inorganic-organic hybrid materials. Guangzi Xuebao/Acta Photonica Sinica, 2009, 38(11): 2756-2760.

4. Lihe Yan, Juanjuan Yue, Jinhai Si, Sen Jia, Feng Chen, Xun Hou. Polarization dependence of femtosecond optical Kerr signals in bismuth glasses. IEEE Photonics Technology Letters, 2009, 21(21): 1606-1608.

3. Lihe Yan, Jinhai Si, Feng Chen, Sen Jia, Yanpeng Zhang, Xun Hou. Pump power dependence of Kerr signals in femtosecond cross pump-probe optical Kerr measurements. Optics Express, 2009, 17(24): 21509-21514.

2. Juanjuan Yue, Lihe Yan, Jinhai Si, Feng Chen, Qing Yang, Xun Hou, Guodong Qian, Jiayu Guo. Polarization dependence of optical Kerr effect in metallophthalocyanine-doped inorganic-organic hybrid materials. Optics Communications, 2009, 282(7): 1448-1451.

1. Lihe Yan, Juanjuan Yue, Jinhai Si, Xun Hou. Influence of self-diffraction effect on femtosecond pump-probe optical Kerr measurements. Optics Express, 2008, 16(16): 12069-12074.