基本信息

 

 

李会霞,生物化学与分子生物学博士,副教授。2016年毕业于西安交通大学留校工作至今,一直从事脂肪组织功能与能量代谢调节、骨组织代谢等研究。2018-2019年于美国加州大学旧金山分校公派留学。

联系方式

联系地址:陕西省西安市雁塔西路76号西安交通大学医学部基础医学院

邮箱:lihuixia@xjtu.edu.cn

站点计数器

主持项目

没有找到条目。
项目编号 项目名称 项目来源 起讫时间 承担角色 项目类别
2022JM-441 自噬通过YAP/TAZ信号调控骨髓间充质干细胞分化命运及其在骨稳态中的作用 陕西省自然科学基础研究计划 2022-01~2023-12 负责人 横向项目
81600621 自噬调控Sirt1/PGC-1α信号对肥胖症脂肪 组织糖脂代谢的作用机制研究 国家自然科学基金项目 2016-01~2019-12 负责人 横向项目
2016M592803 Progranulin 对脂肪组织慢性炎症反应的作用机制研究 中国博士后科学基金 2016-01~2017-12 负责人 横向项目

代表论文

1. Li, Huixia; Zhang, Zhuanmin; Feng, Dongxu; Xu, Lin; Li, Fang; Liu, Jiali; Jin, Xinxin; Qi
an, Zhuang; Kang, Xiaomin; Sun, Hongzhi ; PGRN exerts inflammatory effects via SIRT1-NF-κB in adipose insulin resistance, 

Journal of Molecular Endocrinology, 2020, 64(3): 181-193

 

2. Li, Huixia; Li, Danhui; Ma, Zhengmin; Qian, Zhuang; Kang, Xiaomin; Jin, Xinxin; Li, Fang;
Wang, Xinluan; Chen, Qian; Sun, Hongzhi; Wu, Shufang ; Defective autophagy in osteoblasts induces
endoplasmic reticulum stress and causes remarkable bone loss, Autophagy, 2018, 14(10): 1726-1741

3. Li, Huixia; Zhou, Bo; Liu, Jiali; Li, Fang; Li, Yulong; Kang, Xiaomin; Sun, Hongzhi; Wu,
Shufang ; Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity
via PERK-eIF2 alpha-dependent manner, Cell Cycle, 2015, 14(12): 1893-1907 
4.Li, Huixia; Zhou, Bo; Xu, Lin; Liu, Jiali; Zang, Weijin; Wu, Shufang; Sun, Hongzhi ; Circ
ulating PGRN Is Significantly Associated With Systemic Insulin Sensitivity and Autophagic Activit
y in Metabolic Syndrome, Endocrinology, 2014, 155(9): 3493-3507 
5. Li, Huixia; Zhou, Bo; Xu, Lin; Liu, Jiali; Zang, Weijin; Wu, Shufang; Sun, Hongzhi ; The
reciprocal interaction between autophagic dysfunction and ER stress in adipose insulin resistance
, Cell Cycle, 2014, 13(4): 565-579 

6. Progranulin modulates cartilage-specific gene expression via sirtuin 1-mediated deacetylation of the transcription factors SOX9 and P65. Feng, Dongxu; Kang, Xiaomin; Wang, Ruiqi; Chen, He; Zhang, Kun; Feng, Weilou; Li, Huixia; Zhu, Yangjun*; Wu, Shufang*JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 295(39): 13640-13650

7. Postnatal Conditional Deletion of Bmal1 in Osteoblasts Enhances Trabecular Bone Formation Via Increased BMP2 SignalsQian, Zhuang; Zhang, Ying; Kang, Xiaomin; Li, Huixia; Zhang, Yan; Jin, Xinxin; Gao, Xin; Xu, Mao; Ma, Zhengmin; Zhao, Liting; Zhang, Zhuanmin; Sun, Hongzhi*; Wu, Shufang*.Journal of Bone and Mineral Research, 2020, 35(8): 1481-1493.

8. Neuropeptide Y Acts Directly on Cartilage Homeostasis and Exacerbates Progression of Osteoarthritis Through NPY2R.Kang, Xiaomin; Qian, Zhuang; Liu, Jiali; Feng, Dongxu; Li, Huixia; Zhang, Zhuanmin; Jin, Xinxin; Ma, Zhengmin; Xu, Mao; Li, Fang; Zhang, Ying; Gao, Xin; Sun, Hongzhi*; Wu, Shufang*.Journal of Bone and Mineral Research, 2020, 35(7): 1375-1384

9. Adipose-specific knockdown of Sirt1 results in obesity and insulin resistance by promoting exosomes release. Li, Fang; Li, Huixia; Jin, Xinxin; Zhang, Ying; Kang, Xiaomin; Zhang, Zhuanmin; Xu, Mao; Qian, Zhuang; Ma, Zhengmin; Gao, Xin; Zhao, Liting; Wu, Shufang*; Sun, Hongzhi*. Cell Cycle, 2019, 18(17): 2067-2082